Hydroxychloroquine 200mg

Generic For: Plaquenil

Hydroxychloroquine 200mg (brand name Plaquenil) is an antimalarial medication also widely prescribed for autoimmune conditions such as lupus and rheumatoid arthritis. It works by calming overactive immune responses and interfering with the malaria parasite. After a licensed provider reviews your prescription, your order ships from a licensed U.S. pharmacy.

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Buy Hydroxychloroquine 200mg (Plaquenil) Online

An antimalarial and disease-modifying antirheumatic drug (DMARD) for lupus, rheumatoid arthritis, and malaria

Hydroxychloroquine 200mg Quick Facts

Drug classAntimalarial / DMARD
TreatsLupus, rheumatoid arthritis, malaria prevention and treatment
FormTablet
Typical dosingTake 2 tabs daily for 5 days within 24 hours of symptoms for treatment or Take 2 tablets weekly for prevention.
Prescription requiredYes — prescription only

What Is Hydroxychloroquine 200mg?

Hydroxychloroquine is a prescription tablet sold under the brand name Plaquenil. It was originally developed to prevent and treat malaria, and it is also FDA-approved for chronic autoimmune conditions including systemic lupus erythematosus, discoid lupus, and rheumatoid arthritis. In autoimmune disease, it helps reduce inflammation, joint pain, and skin symptoms over weeks to months of regular use. It is taken by mouth, usually once or twice daily with food or milk to reduce stomach upset.

What Does Hydroxychloroquine 200mg Treat?

Systemic lupus erythematosus (SLE)
Chronic discoid lupus erythematosus
Rheumatoid arthritis
Prevention (prophylaxis) of malaria
Treatment of uncomplicated malaria caused by susceptible strains

Hydroxychloroquine 200mg Dosage

Lupus: 200–400 mg by mouth daily (once daily or in two divided doses).
Rheumatoid arthritis: 400–600 mg by mouth daily initially; maintenance 200–400 mg daily. Do not exceed 400 mg/day (or 5 mg/kg/day) long term.
Malaria prophylaxis: 400 mg by mouth once weekly, starting 2 weeks before exposure and continuing 4 weeks after leaving the endemic area.

Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.

Hydroxychloroquine 200mg Side Effects

Common side effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Stomach cramps
  • Headache
  • Dizziness
  • Skin rash or itching
  • Loss of appetite

Serious side effects

Stop taking this medication and seek medical attention right away if you experience:

  • Vision changes or blurred vision (possible retinal damage)
  • Irregular heartbeat, fainting, or QT prolongation
  • Severe low blood sugar (hypoglycemia)
  • Unusual bruising, bleeding, or signs of low blood counts
  • Muscle weakness or nerve problems
  • Severe skin reactions (blistering, peeling rash)

Warnings & Interactions

Risk of irreversible retinal toxicity; regular eye exams are required with long-term use
May cause QT prolongation and serious heart rhythm problems, especially with other QT-prolonging drugs
Do not use if you have a known allergy to hydroxychloroquine or 4-aminoquinoline compounds
Use caution with G6PD deficiency, liver disease, kidney disease, or psoriasis
Can cause severe hypoglycemia, including in patients not taking diabetes medication
May increase digoxin levels and interact with certain antiepileptics and other medications
Cardiomyopathy has been reported with long-term use

Tell your prescriber about all medications, supplements, and health conditions before starting hydroxychloroquine 200mg.

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Frequently Asked Questions

What is hydroxychloroquine used for?

Hydroxychloroquine is FDA-approved to treat systemic and discoid lupus, rheumatoid arthritis, and to prevent and treat certain types of malaria. In autoimmune conditions it helps reduce inflammation, joint pain, and skin flares. It may take several weeks to months to feel its full effect.

Is hydroxychloroquine the same as Plaquenil?

Yes. Plaquenil is the brand name for hydroxychloroquine sulfate, and the generic tablet contains the same active ingredient in the same 200mg strength. Both are held to the same FDA standards for quality and effectiveness.

Do I need a prescription for hydroxychloroquine?

Yes. Hydroxychloroquine is a prescription-only medication in the United States. A licensed healthcare provider must evaluate you and issue a valid prescription before this medication can be dispensed.

How does ordering and shipping work?

After you place your order, a licensed provider or pharmacist reviews your prescription and health information. Once approved, your medication is filled and shipped from a licensed U.S. pharmacy directly to your address.

How long does hydroxychloroquine take to work?

For lupus and rheumatoid arthritis, many patients begin to notice improvement within 4 to 12 weeks, though full benefit can take up to 6 months. Take it consistently as prescribed and do not stop without talking to your provider.

Why do I need eye exams while taking hydroxychloroquine?

Long-term use can, in rare cases, cause damage to the retina that may be irreversible. Your prescriber will typically recommend a baseline eye exam and periodic screening so any changes can be caught early.

Can I take hydroxychloroquine with food?

Yes — taking hydroxychloroquine with food or a glass of milk is recommended to reduce nausea and stomach upset. Take it at the same time each day to help maintain steady levels.