Ketoconazole 2% Shampoo
Ketoconazole shampoo 2% is a prescription-strength antifungal used to treat tinea versicolor and commonly prescribed for seborrheic dermatitis and flaking, itchy scalp conditions caused by yeast. It works by stopping the growth of fungi on the skin and scalp. After a licensed provider reviews your information, your order ships from a licensed U.S. pharmacy.
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42-day supply · $0.29/mL
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Prescription antifungal shampoo for tinea versicolor, seborrheic dermatitis, and stubborn dandruff
Ketoconazole 2% Shampoo Quick Facts
| Drug class | Azole antifungal (topical) |
|---|---|
| Treats | Tinea versicolor, seborrheic dermatitis, dandruff |
| Form | Liquid |
| Typical dosing | Apply to wet scalp, lather, leave on for 3 - 5 minutes, then rinse thoroughly. Use 2–3 times per week. |
| Prescription required | Yes — prescription only |
What Is Ketoconazole 2% Shampoo?
Ketoconazole shampoo 2% is a topical antifungal medication applied to the skin or scalp. It belongs to the azole class of antifungals, which work by preventing fungi and yeast from producing a substance they need to build their cell membranes. The 2% strength is FDA-approved to treat tinea versicolor, a fungal infection that causes discolored patches on the skin, and it is widely prescribed for seborrheic dermatitis and dandruff. Unlike the 1% version sold over the counter, ketoconazole 2% shampoo requires a prescription in the United States.
What Does Ketoconazole 2% Shampoo Treat?
Tinea versicolor (pityriasis versicolor)
Seborrheic dermatitis of the scalp
Dandruff with flaking and itching
Yeast-related scalp scaling and irritation
Fungal overgrowth on skin folds (as directed by a provider)
Ketoconazole 2% Shampoo Dosage
Tinea versicolor: Apply to damp skin of affected area and a wide surrounding margin, lather, leave in place 5 minutes, then rinse. One application.
Seborrheic dermatitis (common off-label regimen per provider): Apply to wet scalp, lather, leave 3–5 minutes, rinse; typically twice weekly for 2–4 weeks, then as directed.
Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.
Ketoconazole 2% Shampoo Side Effects
Common side effects
- Itching or skin irritation at application site
- Dry skin or scalp
- Abnormal hair texture
- Mild scalp pustules
- Oily or dry hair
- Stinging where applied
- Rash
Serious side effects
Stop taking this medication and seek medical attention right away if you experience:
- Severe allergic reaction (hives, swelling of face or throat, trouble breathing)
- Severe blistering, peeling, or open sores at application site
- Significant hair loss
- Severe burning or worsening irritation
Warnings & Interactions
For external use only; do not swallow and avoid contact with eyes
Do not use if allergic to ketoconazole or any ingredient in the shampoo
May cause hair discoloration, particularly in chemically damaged or gray hair
Tell your provider if you are pregnant or breastfeeding before use
Stop use and contact your provider if severe irritation or allergic reaction occurs
Hair loss has been reported rarely; report unusual shedding to your provider
Tell your prescriber about all medications, supplements, and health conditions before starting ketoconazole 2% shampoo.
Sources & References
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