Methylcobalamin B12 5mg/mL
Methylcobalamin B12 5mg/mL is an injectable, active form of vitamin B12 prescribed to treat and prevent vitamin B12 deficiency, including deficiency caused by pernicious anemia or poor absorption. Because it is given by injection, it bypasses the digestive tract, making it useful for patients who cannot absorb B12 from food or oral supplements. After a licensed provider reviews your prescription, your order ships from a licensed U.S. pharmacy.
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30-day supply · $7.90/mL
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An injectable form of vitamin B12 used for vitamin B12 deficiency, pernicious anemia, and B12-related nerve health support
Methylcobalamin B12 5mg/mL Quick Facts
| Drug class | Vitamin B12 supplement |
|---|---|
| Treats | Vitamin B12 deficiency, pernicious anemia, malabsorption-related deficiency |
| Form | Injection |
| Typical dosing | Follow Instruction sheet attached. |
| Prescription required | Yes — prescription only |
What Is Methylcobalamin B12 5mg/mL?
Methylcobalamin is one of the active, naturally occurring forms of vitamin B12, an essential nutrient the body needs to make red blood cells, maintain nerve function, and support DNA synthesis. This 5mg/mL injectable formulation delivers B12 directly into muscle or under the skin, which is important for people whose bodies cannot absorb the vitamin through the stomach and intestines. It is commonly prescribed for vitamin B12 deficiency, pernicious anemia, and deficiency related to gastrointestinal conditions or surgery. Methylcobalamin injection requires a prescription and is administered on a schedule set by your healthcare provider.
What Does Methylcobalamin B12 5mg/mL Treat?
Vitamin B12 deficiency
Pernicious anemia
Megaloblastic anemia due to B12 deficiency
B12 deficiency from malabsorption (e.g., after gastric surgery, Crohn's disease, celiac disease)
Dietary B12 deficiency (e.g., strict vegan diets)
B12 deficiency associated with certain medications (e.g., metformin, acid reducers)
Maintenance therapy to prevent recurrence of B12 deficiency
Methylcobalamin B12 5mg/mL Dosage
Typical: 1,000 mcg (0.2 mL) IM or SC daily to weekly initially, then monthly for maintenance.
Dose, frequency, and duration are individualized by your prescriber based on labs and indication.
Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.
Methylcobalamin B12 5mg/mL Side Effects
Common side effects
- Pain, redness, or swelling at injection site
- Mild diarrhea
- Nausea
- Headache
- Dizziness
- Itching or mild rash
- Feeling of swelling over the body
Serious side effects
Stop taking this medication and seek medical attention right away if you experience:
- Allergic reaction or anaphylaxis (hives, swelling of face/throat, difficulty breathing)
- Symptoms of low potassium (muscle weakness, cramps, irregular heartbeat)
- Signs of pulmonary edema or heart failure (shortness of breath, rapid weight gain, swelling)
- Chest pain or palpitations
- Blood clot symptoms (leg pain, swelling, warmth)
Warnings & Interactions
Do not use if allergic to cobalamin (vitamin B12) or cobalt.
Hypokalemia (low potassium) may occur during early treatment of severe deficiency; monitoring may be needed.
B12 therapy can mask folate deficiency; both should be evaluated before treatment.
Use with caution in Leber's hereditary optic neuropathy; B12 may worsen optic atrophy.
Some medications (metformin, proton pump inhibitors, colchicine) can reduce B12 levels or absorption.
Tell your provider if you are pregnant, breastfeeding, or have kidney disease.
Compounded methylcobalamin injections are not FDA-approved products; use only as directed by your prescriber.
Tell your prescriber about all medications, supplements, and health conditions before starting methylcobalamin b12 5mg/ml.
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