Methylene Blue 30mg

Methylene Blue 30mg is a prescription capsule containing methylene blue, a redox agent best known for treating acquired methemoglobinemia — a blood disorder that reduces oxygen delivery to tissues. It has also historically been used as a urinary antiseptic. After a licensed provider reviews your prescription, your order ships from a licensed U.S. pharmacy.

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30-day supply · $2.00/capsule

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Methylene blue is an oxidation-reduction (redox) agent used to treat acquired methemoglobinemia and certain urinary tract conditions.

Methylene Blue 30mg Quick Facts

Drug classOxidation-reduction (redox) agent
TreatsAcquired methemoglobinemia, urinary tract antiseptic (historical use)
FormCapsule
Typical dosingTake 1 capsule by mouth daily.
Prescription requiredYes — prescription only

What Is Methylene Blue 30mg?

Methylene blue is a medication classified as an oxidation-reduction agent. Its primary FDA-recognized use is treating acquired methemoglobinemia, a condition in which an abnormal form of hemoglobin prevents red blood cells from carrying oxygen effectively. Methylene blue works by helping convert methemoglobin back to normal hemoglobin so blood can transport oxygen properly. The 30mg capsule form is dispensed by prescription and should be taken exactly as directed by your healthcare provider.

What Does Methylene Blue 30mg Treat?

Acquired methemoglobinemia
Drug-induced methemoglobinemia
Chemical-induced methemoglobinemia
Urinary tract antiseptic (historical/adjunctive use)
Diagnostic dye and visualization aid (procedural use)

Methylene Blue 30mg Dosage

Methemoglobinemia (FDA-approved injectable labeling): 1 mg/kg IV over 5–30 minutes; may repeat once after 1 hour if needed.
Oral capsules: take exactly as prescribed by your provider; dosing is individualized.

Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.

Methylene Blue 30mg Side Effects

Common side effects

  • Blue or blue-green discoloration of urine
  • Blue discoloration of skin or stool
  • Nausea
  • Vomiting
  • Headache
  • Dizziness
  • Altered sense of taste
  • Sweating

Serious side effects

Stop taking this medication and seek medical attention right away if you experience:

  • Serotonin syndrome (agitation, confusion, rapid heart rate, fever)
  • Hemolytic anemia, especially with G6PD deficiency
  • Severe allergic reaction (anaphylaxis)
  • Paradoxical worsening of methemoglobinemia at high doses
  • Chest pain or irregular heartbeat

Warnings & Interactions

Do not use with serotonergic drugs (SSRIs, SNRIs, MAOIs) — risk of serotonin syndrome
Contraindicated in G6PD deficiency — risk of hemolysis
Contraindicated with known hypersensitivity to methylene blue or thiazine dyes
May cause fetal harm — discuss risks if pregnant or breastfeeding
Can interfere with pulse oximetry readings
Use caution in severe renal impairment
Expect harmless blue-green discoloration of urine and stool

Tell your prescriber about all medications, supplements, and health conditions before starting methylene blue 30mg.

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Frequently Asked Questions

What is methylene blue?

Methylene blue is a prescription medication classified as an oxidation-reduction agent. Its main FDA-recognized use is treating acquired methemoglobinemia, a blood condition that reduces the blood's ability to carry oxygen. It has also been used historically as a urinary antiseptic and as a dye in medical procedures.

What is methylene blue used for?

The primary approved use is treating acquired methemoglobinemia caused by certain drugs or chemicals. Any other use of methylene blue capsules should be discussed with and directed by your healthcare provider.

Do I need a prescription for methylene blue capsules?

Yes. Methylene Blue 30mg capsules require a valid prescription from a licensed healthcare provider. A pharmacist and provider review each order before it is dispensed.

How does ordering and shipping work?

After you place your order and submit your prescription, a licensed provider and pharmacist review it for safety and appropriateness. Once approved, your medication ships directly from our licensed U.S. pharmacy.

Can methylene blue interact with antidepressants?

Yes, this is an important safety concern. Methylene blue can cause serious serotonin syndrome when combined with SSRIs, SNRIs, MAOIs, and other serotonergic medications. Always tell your provider about every medication and supplement you take.

Why does methylene blue turn urine blue?

Methylene blue is a dye, and blue or blue-green discoloration of urine, stool, and sometimes skin is expected and harmless. The discoloration resolves after the medication clears from your body.

Is methylene blue safe for everyone?

No. It should not be used by people with G6PD deficiency, those taking serotonergic medications, or anyone with a known allergy to thiazine dyes. Your provider will review your health history before prescribing.