Tizanidine 4mg
Generic For: Zanaflex
Tizanidine 4mg (brand name Zanaflex) is a prescription muscle relaxant used to manage spasticity — tight, stiff muscles caused by conditions such as multiple sclerosis or spinal cord injury. Many patients comparing options like tizanidine vs cyclobenzaprine are prescribed tizanidine for its short-acting relief of muscle tightness. After a licensed provider reviews your prescription, your order ships from a licensed U.S. pharmacy.
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Buy Tizanidine 4mg (Zanaflex) Online
A short-acting muscle relaxant for spasticity from multiple sclerosis, spinal cord injury, and muscle spasms
Tizanidine 4mg Quick Facts
| Drug class | Central alpha-2 adrenergic agonist |
|---|---|
| Treats | Spasticity, muscle tightness from MS, spinal cord injury |
| Form | Tablet |
| Typical dosing | Take 1 tablet by mouth 3 times a day as needed for muscle spasm. |
| Prescription required | Yes — prescription only |
What Is Tizanidine 4mg?
Tizanidine is a short-acting skeletal muscle relaxant classified as a central alpha-2 adrenergic agonist. It works in the central nervous system to reduce nerve signals that cause muscles to tighten, helping relieve spasticity. It is FDA-approved for the management of spasticity, which commonly occurs with multiple sclerosis, spinal cord injury, and other neurological conditions. If you are weighing tizanidine vs cyclobenzaprine, note that they belong to different drug classes and are used for different primary indications — your provider can determine which fits your situation.
What Does Tizanidine 4mg Treat?
Management of spasticity
Muscle tightness related to multiple sclerosis
Muscle spasticity from spinal cord injury
Spasticity from other neurological conditions (as directed by a provider)
Short-term relief during daily activities when spasticity relief is most important
Tizanidine 4mg Dosage
Start: 2 mg by mouth every 6–8 hours as needed; max 3 doses in 24 hours.
Titrate: increase by 2–4 mg per dose as tolerated over 1–4 days.
Max: 16 mg per single dose; 36 mg per day.
Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.
Tizanidine 4mg Side Effects
Common side effects
- Dry mouth
- Drowsiness or sedation
- Dizziness
- Weakness or fatigue (asthenia)
- Low blood pressure
- Constipation
- Urinary tract infection
- Nervousness
Serious side effects
Stop taking this medication and seek medical attention right away if you experience:
- Severe low blood pressure or fainting
- Signs of liver injury (yellowing skin/eyes, dark urine, abdominal pain)
- Hallucinations or confusion
- Slow heart rate (bradycardia)
- Severe allergic reaction (rash, swelling, trouble breathing)
- Extreme sedation or unresponsiveness
Warnings & Interactions
Do not take with fluvoxamine or ciprofloxacin (contraindicated CYP1A2 interaction)
May cause significant low blood pressure; rise slowly from sitting or lying down
Risk of liver injury; liver function monitoring may be needed
Causes sedation; avoid alcohol and use caution with other CNS depressants
Do not stop abruptly — taper to avoid rebound high blood pressure and increased spasticity
Use caution with kidney or liver impairment
Taking with or without food changes absorption; take it the same way each time
Tell your prescriber about all medications, supplements, and health conditions before starting tizanidine 4mg.
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