Amoxicillin 400mg/5mL

Generic For: Amoxil

Amoxicillin 400mg/5mL (brand name Amoxil) is a penicillin-class antibiotic oral suspension used to treat bacterial infections such as sinus infections, tooth infections, ear infections, and throat infections. Many patients ask about taking amoxicillin and prednisone together for sinus or dental infections — a licensed provider can review whether that combination is appropriate for you. Your order ships from a licensed U.S. pharmacy after a provider reviews your prescription.

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10-day supply · $0.25/mL

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Buy Amoxicillin 400mg/5mL (Amoxil) Suspension Online

A penicillin-class antibiotic for sinus infections, tooth infections, and ear infections

Amoxicillin 400mg/5mL Quick Facts

Drug classPenicillin-class antibiotic
TreatsSinus infections, tooth infections, ear infections, throat infections
FormSuspension
Typical dosingFill amber bottle with water to the fill line. Follow label directions. Children 45 - 90 lbs: take 5 mL by mouth every 12 hrs for 10 days. Use within 14 days after mixing and discard any remainder.
Prescription requiredYes — prescription only

What Is Amoxicillin 400mg/5mL?

Amoxicillin is a penicillin-class antibiotic that works by stopping the growth of susceptible bacteria. The 400mg/5mL strength is a liquid suspension, which makes it easier to take for people who have difficulty swallowing tablets or capsules. It is commonly prescribed for sinus infections and tooth infections, and some providers pair amoxicillin and prednisone when significant inflammation is present. Amoxicillin treats bacterial infections only and does not work against viral illnesses like colds or the flu.

What Does Amoxicillin 400mg/5mL Treat?

Sinusitis (sinus infections)
Dental infections (tooth infections)
Ear, nose, and throat infections (including otitis media and strep throat)
Lower respiratory tract infections (such as pneumonia)
Urinary tract infections
Skin and skin structure infections
H. pylori eradication (as part of combination therapy)

Amoxicillin 400mg/5mL Dosage

Mild/moderate infections: 500 mg by mouth every 12 hours OR 250 mg every 8 hours
Severe infections: 875 mg by mouth every 12 hours OR 500 mg every 8 hours
Shake suspension well before each dose; complete the full prescribed course

Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.

Amoxicillin 400mg/5mL Side Effects

Common side effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Headache
  • Stomach upset
  • Rash
  • Changes in taste

Serious side effects

Stop taking this medication and seek medical attention right away if you experience:

  • Severe allergic reaction (hives, swelling, trouble breathing)
  • Severe or persistent watery/bloody diarrhea (C. difficile)
  • Severe skin reactions (blistering, peeling rash)
  • Yellowing of skin or eyes (liver problems)
  • Unusual bruising or bleeding

Warnings & Interactions

Do not use if allergic to penicillins or cephalosporin cross-reactivity is a concern
Serious, sometimes fatal, anaphylactic reactions have been reported
May cause C. difficile–associated diarrhea, including months after treatment
Use with allopurinol may increase risk of rash
May reduce effectiveness of oral contraceptives; consider backup contraception
Probenecid increases amoxicillin blood levels
Dose adjustment needed in severe kidney impairment

Tell your prescriber about all medications, supplements, and health conditions before starting amoxicillin 400mg/5ml.

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Frequently Asked Questions

Can I take prednisone and amoxicillin together?

Prednisone and amoxicillin are sometimes prescribed together because there is no major known interaction between them. Amoxicillin treats the bacterial infection while prednisone reduces inflammation. Only take both if a licensed provider has prescribed them for you.

Are amoxicillin and prednisone used for a sinus infection?

Providers sometimes prescribe amoxicillin and prednisone for sinus infection symptoms when a bacterial infection is accompanied by significant swelling or inflammation. Amoxicillin targets the bacteria and prednisone helps reduce sinus inflammation. Your provider will decide if this combination is appropriate for your case.

Are amoxicillin and prednisone used for a tooth infection?

Amoxicillin is a common first-line antibiotic for dental infections, and prednisone may occasionally be added to manage severe swelling. However, tooth infections often also require dental treatment such as drainage or a root canal. See a dentist promptly and follow your provider's guidance.

Do I need a prescription for Amoxicillin 400mg/5mL?

Yes. Amoxicillin is a prescription-only medication in the United States. A licensed healthcare provider must evaluate you and issue a valid prescription before this medication can be dispensed.

How does ordering and shipping work?

After you place your order, a licensed provider reviews your prescription and health information. Once approved, your medication is dispensed and shipped directly from a licensed U.S. pharmacy. Contact our pharmacy team if you have questions about your order status.

How should I take the amoxicillin suspension?

Shake the bottle well before each dose and measure with the provided dosing device, not a household spoon. Take it exactly as prescribed and finish the entire course even if you feel better. Stopping early can allow the infection to return.

What should I do if I miss a dose?

Take the missed dose as soon as you remember, unless it is almost time for your next dose. Do not double up on doses. If you are unsure, contact your pharmacist for guidance.