Bupropion HCL ER 150mg

Generic For: Wellbutrin XL

Bupropion HCL ER 150mg is the extended-release form of bupropion, the generic version of Wellbutrin XL. It is an atypical antidepressant prescribed to treat major depressive disorder (MDD) and to prevent seasonal affective disorder (SAD). After a licensed provider reviews your prescription, your medication ships directly from our licensed U.S. pharmacy.

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Buy Bupropion HCL ER 150mg Online (Wellbutrin XL)

Bupropion HCL ER is an atypical antidepressant used for major depressive disorder and seasonal affective disorder

Bupropion HCL ER 150mg Quick Facts

Drug classAminoketone antidepressant
TreatsMajor depressive disorder, seasonal affective disorder
FormTablet
Typical dosingTake 1 tablet by mouth daily
Prescription requiredYes — prescription only

What Is Bupropion HCL ER 150mg?

Bupropion HCL ER is an extended-release antidepressant tablet, sold under the brand name Wellbutrin XL. It works differently from SSRIs, affecting the brain chemicals norepinephrine and dopamine, and is generally less associated with sexual side effects or weight gain. The extended-release design allows for convenient once-daily dosing. It is FDA-approved for major depressive disorder and for the prevention of seasonal affective disorder.

What Does Bupropion HCL ER 150mg Treat?

Major depressive disorder (MDD)
Prevention of seasonal affective disorder (SAD)
Sometimes prescribed off-label for smoking cessation (bupropion SR is the approved form)
Sometimes prescribed off-label for depression with fatigue or low energy
Sometimes used off-label as an adjunct to other antidepressants

Bupropion HCL ER 150mg Dosage

MDD: Take 150mg by mouth once daily in the morning; may increase to 300mg once daily after at least 4 days as directed.
SAD prevention: Take 150mg by mouth once daily in the morning, starting in autumn; may increase to 300mg once daily after 1 week as directed.
Swallow tablets whole; do not crush, chew, or divide.

Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.

Bupropion HCL ER 150mg Side Effects

Common side effects

  • Dry mouth
  • Insomnia (trouble sleeping)
  • Headache
  • Nausea
  • Dizziness
  • Constipation
  • Sweating
  • Agitation or anxiety

Serious side effects

Stop taking this medication and seek medical attention right away if you experience:

  • Seizures
  • Suicidal thoughts or behavior, especially in young adults
  • Severe allergic reaction (rash, hives, swelling, trouble breathing)
  • Severe or sudden increase in blood pressure
  • Unusual mood changes, hallucinations, or confusion
  • Vision changes or eye pain (possible angle-closure glaucoma)

Warnings & Interactions

Boxed warning: increased risk of suicidal thoughts and behaviors in children, adolescents, and young adults
Do not use if you have a seizure disorder or current/prior diagnosis of anorexia or bulimia
Do not use during or within 14 days of MAOI therapy
Do not use if abruptly stopping alcohol, benzodiazepines, or other sedatives
Do not take with other bupropion products (risk of seizure from excess dose)
Alcohol can increase the risk of seizures; limit or avoid while taking this medication
Can raise blood pressure; monitor if you have hypertension

Tell your prescriber about all medications, supplements, and health conditions before starting bupropion hcl er 150mg.

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Frequently Asked Questions

What is bupropion HCL ER used for?

Bupropion HCL ER is FDA-approved to treat major depressive disorder and to prevent seasonal affective disorder. It is the generic version of Wellbutrin XL and is taken once daily.

Is bupropion HCL ER the same as Wellbutrin XL?

Yes, bupropion HCL ER is the generic equivalent of brand-name Wellbutrin XL. It contains the same active ingredient at the same strength and is held to the same FDA standards.

Do I need a prescription for bupropion HCL ER 150mg?

Yes, bupropion HCL ER is a prescription-only medication in the United States. A licensed healthcare provider must evaluate whether it is appropriate for you before it can be dispensed.

How does ordering and shipping work?

After you place your order, a licensed provider or pharmacist reviews your prescription and health information. Once approved, your medication ships from our licensed U.S. pharmacy directly to your door.

How long does bupropion HCL ER take to work?

Some people notice improvement in sleep, energy, or appetite within the first 1–2 weeks, but the full antidepressant effect may take 4–6 weeks or longer. Continue taking it as prescribed and talk to your provider before making changes.

Can I drink alcohol while taking bupropion HCL ER?

Drinking alcohol while taking bupropion can increase the risk of seizures, and suddenly stopping heavy alcohol use while on bupropion is also dangerous. Talk to your provider about your alcohol use before starting this medication.

What should I do if I miss a dose?

Skip the missed dose and take your next dose at the regular time. Never take two doses at once or take doses too close together, as this increases the risk of seizures.