Diclofenac 3% Gel

Generic For: Voltaren Gel

Diclofenac 3% Gel is a prescription topical NSAID applied directly to the skin to treat actinic keratosis — rough, scaly patches caused by sun damage. After a licensed provider reviews your health information and confirms a valid prescription, your order ships discreetly from a licensed U.S. pharmacy.

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60-day supply · $0.60/gram

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  3. Our licensed U.S. pharmacists fill your prescription
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Price: $60.00

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A topical NSAID (nonsteroidal anti-inflammatory) gel used to treat actinic keratosis on sun-damaged skin

Diclofenac 3% Gel Quick Facts

Drug classTopical NSAID
TreatsActinic keratosis, sun-damaged skin lesions
FormGel
Typical dosingApply a pea sized amount to affected area topically 2-4 times daily as needed for pain.
Prescription requiredYes — prescription only

What Is Diclofenac 3% Gel?

Diclofenac 3% Gel is a prescription-strength topical nonsteroidal anti-inflammatory drug (NSAID). It is applied directly to areas of skin affected by actinic keratosis, a precancerous condition caused by long-term sun exposure. Unlike lower-strength diclofenac gels sold over the counter for joint pain, the 3% strength is FDA-approved specifically for treating actinic keratoses. Treatment typically continues for 60 to 90 days, and full improvement may not be seen until up to 30 days after finishing the course.

What Does Diclofenac 3% Gel Treat?

Actinic keratosis (precancerous, sun-damaged skin lesions)
Actinic keratoses on the face
Actinic keratoses on the scalp
Actinic keratoses on the arms and hands
Other sun-exposed skin areas with actinic keratoses, as directed by your provider

Diclofenac 3% Gel Dosage

Apply enough gel to cover each lesion; smooth in gently, topically, twice daily.
Usual amount: 0.5 g per 5 cm x 5 cm lesion area.
Usual duration: 60 to 90 days as directed.

Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.

Diclofenac 3% Gel Side Effects

Common side effects

  • Dry skin at application site
  • Itching (pruritus)
  • Redness or irritation
  • Rash or scaling
  • Contact dermatitis
  • Skin tingling or numbness (paresthesia)
  • Application site pain

Serious side effects

Stop taking this medication and seek medical attention right away if you experience:

  • Severe allergic reaction (hives, swelling of face or throat, trouble breathing)
  • Severe skin reactions (blistering, peeling, ulceration)
  • Signs of liver problems (yellowing skin or eyes, dark urine, unusual fatigue)
  • Chest pain, weakness, or slurred speech (possible heart attack or stroke)
  • Signs of stomach bleeding (black stools, vomiting blood)
  • Worsening asthma or wheezing

Warnings & Interactions

NSAIDs may increase the risk of serious cardiovascular events, including heart attack and stroke
NSAIDs may increase the risk of serious gastrointestinal bleeding and ulcers
Do not use if you have had asthma, hives, or allergic reactions to aspirin or other NSAIDs
Avoid use on open wounds, infected skin, eyes, and mucous membranes
Minimize sun exposure and avoid tanning during treatment
Avoid use during pregnancy at 20 weeks or later unless directed by a provider
Use caution when combining with oral NSAIDs, anticoagulants, or other blood thinners

Tell your prescriber about all medications, supplements, and health conditions before starting diclofenac 3% gel.

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Frequently Asked Questions

What is diclofenac?

Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) available in several forms, including oral tablets and topical gels. The 3% gel strength is a prescription topical treatment that is FDA-approved for actinic keratosis, a skin condition caused by sun damage.

What is diclofenac DR?

Diclofenac DR refers to delayed-release oral tablets of diclofenac, which are taken by mouth for conditions like arthritis pain. It is a different product from Diclofenac 3% Gel, which is applied to the skin to treat actinic keratosis rather than taken orally.

Do I need a prescription for Diclofenac 3% Gel?

Yes. Diclofenac 3% Gel is a prescription medication in the United States. A licensed provider must review your health information and issue a valid prescription before the pharmacy can dispense it.

How is Diclofenac 3% Gel different from over-the-counter Voltaren gel?

Over-the-counter Voltaren Arthritis Pain Gel contains 1% diclofenac and is used for joint pain. The 3% gel is a stronger, prescription-only formulation approved specifically for treating actinic keratosis on sun-damaged skin.

How long do I need to use Diclofenac 3% Gel?

The usual course of treatment is 60 to 90 days of twice-daily application, as directed by your provider. Lesions may continue to improve for up to 30 days after you finish treatment, so follow your provider's instructions for the full duration.

How does ordering and shipping work?

After you place your order, a licensed provider reviews your health information to confirm the medication is appropriate for you. Once approved, your prescription is filled and shipped discreetly from a licensed U.S. pharmacy.

What are the most common side effects?

The most common side effects are skin reactions at the application site, including dryness, itching, redness, rash, and scaling. Contact your provider if you develop severe irritation, blistering, or signs of an allergic reaction.