Hydralazine 25mg
Generic For: Apresoline
Hydralazine 25mg (brand name Apresoline) is a prescription vasodilator used to treat essential hypertension, either alone or with other blood pressure medications. It works by relaxing the blood vessels so blood can flow more easily. After a licensed provider reviews your prescription, your order ships directly from a licensed U.S. pharmacy.
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100-day supply · $0.30/tablet
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Buy Hydralazine 25mg Online
A vasodilator antihypertensive for high blood pressure and, with nitrates, certain cases of heart failure
Hydralazine 25mg Quick Facts
| Drug class | Vasodilator antihypertensive |
|---|---|
| Treats | High blood pressure, essential hypertension, adjunct in heart failure (with nitrates) |
| Form | Tablet |
| Typical dosing | Take by mouth as directed by physician. |
| Prescription required | Yes — prescription only |
What Is Hydralazine 25mg?
Hydralazine is a prescription medication that lowers blood pressure by directly relaxing the smooth muscle in the walls of small arteries. This widening of blood vessels reduces the resistance the heart must pump against, which lowers blood pressure. It is FDA-approved for essential hypertension and may be used alone or alongside other antihypertensive medicines. Hydralazine 25mg tablets are the generic form of the brand Apresoline.
What Does Hydralazine 25mg Treat?
Essential hypertension (high blood pressure)
Hypertension not controlled by other medications, as add-on therapy
Severe hypertension requiring combination therapy
Heart failure, in combination with isosorbide dinitrate (off-label per prescriber guidance)
Hydralazine 25mg Dosage
Initiate: 10 mg by mouth 4 times daily for the first 2-4 days.
Increase to 25 mg by mouth 4 times daily for the remainder of the first week.
Week 2 and after: 50 mg by mouth 4 times daily; adjust to lowest effective maintenance dose.
Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.
Hydralazine 25mg Side Effects
Common side effects
- Headache
- Rapid heartbeat (tachycardia)
- Palpitations
- Loss of appetite
- Nausea or vomiting
- Diarrhea
- Dizziness
- Flushing
Serious side effects
Stop taking this medication and seek medical attention right away if you experience:
- Chest pain or worsening angina
- Lupus-like syndrome (joint pain, fever, rash, fatigue)
- Numbness or tingling in hands or feet (peripheral neuritis)
- Unexplained fever, sore throat, or unusual bruising (blood disorders)
- Fainting or severe drop in blood pressure
- Swelling, rapid weight gain, or shortness of breath
Warnings & Interactions
May cause a drug-induced lupus-like syndrome, especially at higher doses or with long-term use
Contraindicated in coronary artery disease and mitral valvular rheumatic heart disease
May cause reflex tachycardia and can provoke angina or myocardial ischemia
Peripheral neuritis may occur; pyridoxine (vitamin B6) may be recommended
Additive blood pressure lowering with other antihypertensives, diuretics, and MAO inhibitors
Do not stop abruptly without medical guidance; blood pressure may rise
Periodic blood counts and ANA testing may be advised during prolonged therapy
Tell your prescriber about all medications, supplements, and health conditions before starting hydralazine 25mg.
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