Hydrochlorothiazide 12.5mg

Generic For: Microzide

Hydrochlorothiazide (brand name Microzide) is a thiazide diuretic, or "water pill," prescribed to lower high blood pressure and reduce fluid retention (edema) caused by conditions such as heart failure, kidney disorders, and liver disease. After a licensed provider reviews your prescription, your order ships from a licensed U.S. pharmacy.

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Buy Hydrochlorothiazide 12.5mg Online

A thiazide diuretic for high blood pressure and fluid retention (edema)

Hydrochlorothiazide 12.5mg Quick Facts

Drug classThiazide diuretic
TreatsHigh blood pressure, edema (fluid retention)
FormTablet
Typical dosingTake 1 tablet by mouth daily.
Prescription requiredYes — prescription only

What Is Hydrochlorothiazide 12.5mg?

Hydrochlorothiazide is a prescription thiazide diuretic, commonly called a water pill. It works by helping the kidneys remove excess salt and water from the body through urine, which lowers blood pressure and reduces swelling. Doctors prescribe hydrochlorothiazide for high blood pressure (hypertension), either alone or alongside other blood pressure medicines. It is also used to treat edema associated with heart failure, kidney disease, liver cirrhosis, and certain medications such as corticosteroids and estrogen.

What Does Hydrochlorothiazide 12.5mg Treat?

High blood pressure (hypertension)
Edema associated with congestive heart failure
Edema associated with liver cirrhosis
Edema associated with kidney disorders (nephrotic syndrome, chronic renal failure)
Edema caused by corticosteroid or estrogen therapy

Hydrochlorothiazide 12.5mg Dosage

Hypertension: Take 1 tablet (12.5 mg) by mouth once daily; may increase to 25–50 mg daily as directed.
Edema: 25–100 mg by mouth once daily or in divided doses, as directed by your provider.

Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.

Hydrochlorothiazide 12.5mg Side Effects

Common side effects

  • Increased urination
  • Dizziness or lightheadedness
  • Headache
  • Weakness or fatigue
  • Muscle cramps
  • Upset stomach
  • Increased sensitivity to sunlight

Serious side effects

Stop taking this medication and seek medical attention right away if you experience:

  • Signs of electrolyte imbalance (irregular heartbeat, severe muscle cramps, confusion)
  • Severe dizziness or fainting
  • Allergic reaction (rash, swelling, difficulty breathing)
  • Eye pain or sudden vision changes (acute myopia, angle-closure glaucoma)
  • Severe skin reactions (blistering, peeling)
  • Signs of dehydration (extreme thirst, very dry mouth, decreased urination)

Warnings & Interactions

Do not use if allergic to hydrochlorothiazide or sulfonamide-derived drugs
Contraindicated in patients with anuria (inability to urinate)
May cause low potassium, sodium, or magnesium; periodic blood tests may be needed
Use caution with lithium — hydrochlorothiazide can increase lithium levels
May worsen gout or raise blood sugar in people with diabetes
Can increase sun sensitivity; use sun protection
Tell your provider if you are pregnant, plan to become pregnant, or are breastfeeding

Tell your prescriber about all medications, supplements, and health conditions before starting hydrochlorothiazide 12.5mg.

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Frequently Asked Questions

What is hydrochlorothiazide used for?

Hydrochlorothiazide is a thiazide diuretic used to treat high blood pressure and edema (fluid retention) caused by heart failure, kidney disease, liver cirrhosis, or certain medications. It works by helping your kidneys remove excess salt and water.

Do I need a prescription for hydrochlorothiazide?

Yes, hydrochlorothiazide is a prescription-only medication in the U.S. A licensed healthcare provider must evaluate you and issue a valid prescription before we can dispense it.

How does ordering and shipping work?

Once you place your order and provide a valid prescription, a licensed pharmacist reviews it for accuracy and safety. Your medication then ships directly from our licensed U.S. pharmacy to your door.

Is hydrochlorothiazide the same as Microzide?

Yes, Microzide is a brand name for hydrochlorothiazide. The generic contains the same active ingredient and works the same way at equivalent doses.

How long does hydrochlorothiazide take to work?

Hydrochlorothiazide begins increasing urine output within about 2 hours of a dose. Its full blood pressure–lowering effect may take several weeks; keep taking it as prescribed even if you feel well.

What should I avoid while taking hydrochlorothiazide?

Limit alcohol, which can worsen dizziness, and protect your skin from sun exposure. Talk to your provider before using potassium supplements, salt substitutes, NSAIDs, or lithium, as these can interact with hydrochlorothiazide.

What happens if I miss a dose?

Take the missed dose as soon as you remember, unless it is close to your next scheduled dose. Do not double up; take doses earlier in the day to avoid nighttime urination.