Hydrochlorothiazide 50mg

Generic For: Microzide

Hydrochlorothiazide (brand name Microzide) is a thiazide diuretic, commonly called a water pill, used to treat high blood pressure and edema caused by conditions such as heart failure, kidney disorders, and liver disease. It works by helping your kidneys remove excess salt and water from the body. After a licensed provider reviews your prescription, your order ships from a licensed U.S. pharmacy.

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Buy Hydrochlorothiazide 50mg Online

A thiazide diuretic (water pill) for high blood pressure and fluid retention (edema)

Hydrochlorothiazide 50mg Quick Facts

Drug classThiazide diuretic
TreatsHigh blood pressure, edema, fluid retention from heart failure
FormTablet
Typical dosingTake 1 tablet by mouth daily.
Prescription requiredYes — prescription only

What Is Hydrochlorothiazide 50mg?

Hydrochlorothiazide is a prescription thiazide diuretic, often called a water pill. It helps the kidneys remove extra salt and water from the body through urine, which lowers blood pressure and reduces swelling. It is one of the most widely prescribed medications in the United States for hypertension, used alone or alongside other blood pressure medicines. It is also prescribed to manage edema associated with heart failure, kidney disease, liver cirrhosis, and certain medications such as corticosteroids and estrogen.

What Does Hydrochlorothiazide 50mg Treat?

High blood pressure (hypertension)
Edema associated with congestive heart failure
Edema from liver cirrhosis
Edema from kidney disorders (nephrotic syndrome, chronic renal failure)
Edema caused by corticosteroid or estrogen therapy

Hydrochlorothiazide 50mg Dosage

Hypertension: 25–50 mg by mouth once daily; may increase up to 100 mg daily.
Edema: 25–100 mg by mouth once daily or in divided doses; may be given intermittently (e.g., every other day).

Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.

Hydrochlorothiazide 50mg Side Effects

Common side effects

  • Increased urination
  • Dizziness or lightheadedness
  • Headache
  • Weakness or fatigue
  • Muscle cramps
  • Upset stomach
  • Increased sensitivity to sunlight

Serious side effects

Stop taking this medication and seek medical attention right away if you experience:

  • Signs of electrolyte imbalance (irregular heartbeat, severe muscle cramps, confusion)
  • Severe dizziness or fainting
  • Eye pain or sudden vision changes (acute angle-closure glaucoma)
  • Severe skin reactions or rash
  • Signs of allergic reaction (swelling of face, lips, or throat; trouble breathing)
  • Unusual bleeding or bruising

Warnings & Interactions

Do not use if allergic to hydrochlorothiazide or other sulfonamide-derived drugs
Contraindicated in patients with anuria (inability to urinate)
May cause low potassium, sodium, or magnesium; periodic blood tests are recommended
Use caution with lithium — hydrochlorothiazide can raise lithium levels
May worsen gout or raise blood sugar in patients with diabetes
Can cause dizziness; use care when driving until you know how it affects you
Tell your provider if pregnant or breastfeeding before use

Tell your prescriber about all medications, supplements, and health conditions before starting hydrochlorothiazide 50mg.

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Frequently Asked Questions

What is hydrochlorothiazide used for?

Hydrochlorothiazide is used to treat high blood pressure and to reduce fluid retention (edema) caused by heart failure, kidney disorders, liver cirrhosis, or certain medications. It works by helping the kidneys remove excess salt and water from the body.

Do I need a prescription for hydrochlorothiazide?

Yes. Hydrochlorothiazide is a prescription-only medication in the United States. A licensed healthcare provider must review your health information and issue or verify a valid prescription before we can dispense it.

How does ordering and shipping work?

Place your order online and provide your prescription, or have your provider send it to our pharmacy. After a licensed pharmacist reviews and verifies the prescription, your medication ships directly from our licensed U.S. pharmacy.

Is hydrochlorothiazide the same as Microzide?

Yes. Microzide is a brand name for hydrochlorothiazide. Generic hydrochlorothiazide contains the same active ingredient and is held to the same FDA standards.

When should I take hydrochlorothiazide?

Most people take it once daily in the morning, since it increases urination. Taking it earlier in the day helps avoid waking at night to urinate; follow your prescriber's directions.

What should I avoid while taking hydrochlorothiazide?

Avoid becoming dehydrated, limit alcohol, and use sun protection since the drug can increase sun sensitivity. Tell your provider about all medications you take, especially lithium, NSAIDs, and other blood pressure medicines.

Can hydrochlorothiazide affect my potassium levels?

Yes, it can lower potassium and other electrolytes. Your provider may order periodic blood tests and may recommend potassium-rich foods or a supplement if needed.