Lisinopril-Hydrochlorothiazide 20-25 MG
Generic For: Zestoretic
Lisinopril-hydrochlorothiazide 20-25 MG (brand name Zestoretic) is a prescription tablet that combines an ACE inhibitor with a thiazide diuretic to treat high blood pressure. Lowering blood pressure can reduce the risk of cardiovascular events such as stroke and heart attack. After a licensed provider reviews your prescription, your order ships from a licensed U.S. pharmacy.
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100-day supply · $0.25/tablet
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An ACE inhibitor and thiazide diuretic combination for high blood pressure (hypertension)
Lisinopril-Hydrochlorothiazide 20-25 MG Quick Facts
| Drug class | ACE inhibitor / thiazide diuretic |
|---|---|
| Treats | High blood pressure (hypertension) |
| Form | Tablet |
| Typical dosing | Take 1 tablet by mouth daily. |
| Prescription required | Yes — prescription only |
What Is Lisinopril-Hydrochlorothiazide 20-25 MG?
Lisinopril-hydrochlorothiazide 20-25 MG is a combination tablet containing lisinopril 20 mg, an ACE inhibitor, and hydrochlorothiazide 25 mg, a thiazide diuretic. Lisinopril relaxes blood vessels so blood flows more easily, while hydrochlorothiazide helps the body remove excess salt and water. Together they lower blood pressure more effectively than either medicine alone for many patients. It is typically prescribed when a single medication has not adequately controlled blood pressure.
What Does Lisinopril-Hydrochlorothiazide 20-25 MG Treat?
High blood pressure (hypertension)
Hypertension not adequately controlled on lisinopril alone
Hypertension not adequately controlled on hydrochlorothiazide alone
Reduction of blood pressure to lower cardiovascular risk
Lisinopril-Hydrochlorothiazide 20-25 MG Dosage
Take 1 tablet (20-25 MG) by mouth once daily.
Dose is individualized by titrating the components; maximum lisinopril 80 mg/hydrochlorothiazide 50 mg daily.
Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.
Lisinopril-Hydrochlorothiazide 20-25 MG Side Effects
Common side effects
- Dizziness
- Headache
- Dry cough
- Fatigue
- Low blood pressure (especially when standing)
- Muscle cramps
- Nausea
Serious side effects
Stop taking this medication and seek medical attention right away if you experience:
- Swelling of the face, lips, tongue, or throat (angioedema)
- Fainting or severe dizziness
- High potassium levels (irregular heartbeat, muscle weakness)
- Signs of kidney problems (reduced urination, swelling)
- Severe skin reactions
- Yellowing of skin or eyes (liver problems)
Warnings & Interactions
Do not use during pregnancy — can cause injury or death to the developing fetus
Do not use with a history of angioedema related to ACE inhibitors
Do not combine with sacubitril/valsartan (Entresto) or use within 36 hours of it
Avoid use with aliskiren in patients with diabetes
Do not use if allergic to sulfonamide-derived drugs
Use caution with potassium supplements, potassium-sparing diuretics, NSAIDs, and lithium
Monitor kidney function and electrolytes during treatment
Tell your prescriber about all medications, supplements, and health conditions before starting lisinopril-hydrochlorothiazide 20-25 mg.
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