Loperamide 2mg

Generic For: Imodium

Loperamide 2mg (brand name Imodium) is an antidiarrheal capsule that slows intestinal movement to help control acute and chronic diarrhea and reduce ileostomy output. After a licensed provider reviews your information and issues a prescription, your loperamide order ships from a licensed U.S. pharmacy.

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An antidiarrheal medication for acute diarrhea, chronic diarrhea, and reducing ileostomy output

Loperamide 2mg Quick Facts

Drug classAntidiarrheal (opioid-receptor agonist)
TreatsAcute diarrhea, chronic diarrhea, ileostomy output reduction
FormCapsule
Typical dosingTake 2 capsules by mouth after first loose stool, then 1 capsule after each subsequent loose stool. Do not exceed 4 capsules in 24 hours.
Prescription requiredYes — prescription only

What Is Loperamide 2mg?

Loperamide is an antidiarrheal medication that works by slowing the movement of the intestines, allowing more water to be absorbed and producing firmer, less frequent stools. It acts on opioid receptors in the gut wall but, at recommended doses, does not produce opioid effects in the brain. Prescription loperamide 2mg capsules are used for acute nonspecific diarrhea, chronic diarrhea associated with inflammatory bowel disease, and to reduce the volume of discharge from an ileostomy. It is the same active ingredient found in the brand-name product Imodium.

What Does Loperamide 2mg Treat?

Acute nonspecific diarrhea
Chronic diarrhea associated with inflammatory bowel disease
Reduction of ileostomy output volume
Symptomatic control of loose, watery stools
Management of chronic functional diarrhea (as directed by a provider)

Loperamide 2mg Dosage

Acute diarrhea: 4 mg (2 capsules) by mouth after first loose stool, then 2 mg after each subsequent loose stool; max 16 mg/day.
Chronic diarrhea: 4 mg by mouth initially, then 2 mg after each loose stool until controlled; usual maintenance 4–8 mg/day.
Discontinue if no improvement after 10 days at maximum dose (chronic) or 48 hours (acute).

Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.

Loperamide 2mg Side Effects

Common side effects

  • Constipation
  • Dizziness
  • Nausea
  • Abdominal cramps or discomfort
  • Drowsiness or fatigue
  • Dry mouth
  • Abdominal distention

Serious side effects

Stop taking this medication and seek medical attention right away if you experience:

  • Irregular or fast heartbeat, fainting (possible QT prolongation/torsades de pointes)
  • Severe constipation, abdominal swelling, or ileus
  • Severe allergic reaction (rash, swelling, difficulty breathing)
  • Toxic megacolon in patients with inflammatory bowel disease
  • Severe skin reactions (blistering, peeling rash)

Warnings & Interactions

Boxed warning: doses higher than recommended can cause serious heart rhythm problems (QT prolongation, torsades de pointes) and death
Do not use if you have bloody or black stools, or diarrhea with high fever
Do not use in acute ulcerative colitis or bacterial enterocolitis (e.g., Salmonella, Shigella, Campylobacter)
Contraindicated in children under 2 years of age
Avoid combining with drugs that prolong the QT interval or inhibit its metabolism (e.g., certain antibiotics, antifungals)
Stop use and seek care if diarrhea worsens or abdominal distention develops
Never take more than the prescribed dose; misuse can cause fatal cardiac events

Tell your prescriber about all medications, supplements, and health conditions before starting loperamide 2mg.

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Frequently Asked Questions

What is loperamide used for?

Loperamide is an antidiarrheal used to control acute nonspecific diarrhea, chronic diarrhea associated with inflammatory bowel disease, and to reduce ileostomy output. It works by slowing intestinal movement so stools become firmer and less frequent.

Is loperamide the same as Imodium?

Yes. Loperamide is the active ingredient in the brand-name product Imodium. Prescription loperamide 2mg capsules contain the same medication and work the same way.

Do I need a prescription for loperamide 2mg capsules?

Yes, this product is a prescription-strength formulation and requires a valid prescription. A licensed provider reviews your health information before any prescription is issued or filled.

How does ordering and shipping work?

After you complete your order and health questionnaire, a licensed provider reviews your information. If a prescription is appropriate, your medication is filled and shipped from a licensed U.S. pharmacy to your address.

How much loperamide can I take in a day?

For adults, the maximum prescription dose is 16 mg per day; do not exceed the dose your provider prescribes. Taking higher-than-recommended doses can cause serious and potentially fatal heart rhythm problems.

When should I stop taking loperamide and see a doctor?

Stop and seek medical care if you develop bloody stools, high fever, worsening diarrhea, abdominal swelling, or an irregular heartbeat. For acute diarrhea, contact your provider if symptoms do not improve within 48 hours.

Can loperamide interact with other medications?

Yes. Loperamide should not be combined with drugs that prolong the QT interval or that block its breakdown, such as certain antibiotics and antifungals. Tell your provider about all medications and supplements you take.