Losartan-Hydrochlorothiazide 100-12.5 MG

Generic For: Hyzaar

Losartan-hydrochlorothiazide 100-12.5 MG (brand name Hyzaar) combines an angiotensin II receptor blocker with a thiazide diuretic in one daily tablet. It is FDA-approved to treat high blood pressure and to reduce the risk of stroke in certain patients with hypertension and left ventricular hypertrophy. After a licensed provider reviews your prescription, your order ships from a licensed U.S. pharmacy.

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Buy Losartan-Hydrochlorothiazide 100-12.5 MG Online

An angiotensin II receptor blocker and thiazide diuretic combination for high blood pressure and stroke risk reduction

Losartan-Hydrochlorothiazide 100-12.5 MG Quick Facts

Drug classARB / thiazide diuretic combination
TreatsHigh blood pressure, stroke risk reduction
FormTablet
Typical dosingTake 1 tablet by mouth daily.
Prescription requiredYes — prescription only

What Is Losartan-Hydrochlorothiazide 100-12.5 MG?

Losartan-hydrochlorothiazide 100-12.5 MG is a combination tablet containing losartan potassium, an angiotensin II receptor blocker (ARB), and hydrochlorothiazide, a thiazide diuretic. Losartan relaxes blood vessels by blocking a hormone that narrows them, while hydrochlorothiazide helps the body remove excess salt and water. Together they lower blood pressure more effectively than either medicine alone. It is sold under the brand name Hyzaar and requires a prescription in the United States.

What Does Losartan-Hydrochlorothiazide 100-12.5 MG Treat?

High blood pressure (hypertension)
Hypertension not adequately controlled on monotherapy
Initial therapy in patients likely to need multiple medications
Reduction of stroke risk in hypertensive patients with left ventricular hypertrophy

Losartan-Hydrochlorothiazide 100-12.5 MG Dosage

Hypertension: 1 tablet (100-12.5 mg) by mouth once daily.
Maximum: losartan 100 mg / hydrochlorothiazide 25 mg once daily.
Take at the same time each day, with or without food.

Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.

Losartan-Hydrochlorothiazide 100-12.5 MG Side Effects

Common side effects

  • Dizziness
  • Upper respiratory infection
  • Cough
  • Back pain
  • Fatigue
  • Increased urination
  • Headache

Serious side effects

Stop taking this medication and seek medical attention right away if you experience:

  • Fainting or severe dizziness (low blood pressure)
  • High potassium (irregular heartbeat, muscle weakness)
  • Swelling of the face, lips, tongue, or throat (angioedema)
  • Signs of kidney problems (decreased urination, swelling)
  • Eye pain or sudden vision changes (acute glaucoma, myopia)
  • Severe skin reactions

Warnings & Interactions

Do not use during pregnancy; can cause fetal harm or death
Contraindicated with anuria or hypersensitivity to sulfonamide-derived drugs
Do not combine with aliskiren in patients with diabetes
Avoid potassium supplements or salt substitutes unless directed by your provider
NSAIDs may reduce effectiveness and worsen kidney function
May cause electrolyte imbalances; periodic lab monitoring is recommended
Use caution with lithium; levels may increase

Tell your prescriber about all medications, supplements, and health conditions before starting losartan-hydrochlorothiazide 100-12.5 mg.

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Frequently Asked Questions

What is losartan-hydrochlorothiazide 100-12.5 used for?

It is FDA-approved to treat high blood pressure and to reduce the risk of stroke in certain patients with hypertension and an enlarged heart muscle (left ventricular hypertrophy). It combines two blood pressure medicines in one daily tablet.

Do I need a prescription for losartan-hydrochlorothiazide 100-12.5 MG?

Yes. This medication requires a valid prescription from a licensed U.S. healthcare provider. Our pharmacists verify every prescription before dispensing.

How does ordering and shipping work?

After you place your order, a licensed provider or pharmacist reviews your prescription and health information. Once approved, your medication ships from a licensed U.S. pharmacy in discreet packaging.

Is losartan-hydrochlorothiazide the same as Hyzaar?

Yes. Losartan-hydrochlorothiazide is the generic version of the brand-name medication Hyzaar. Both contain the same active ingredients in the same strengths.

How should I take losartan-hydrochlorothiazide 100-12.5?

The usual dose is one tablet by mouth once daily, with or without food, at the same time each day. Follow your prescriber's instructions and do not change your dose without talking to them.

Can I take this medication during pregnancy?

No. Losartan-hydrochlorothiazide carries an FDA boxed warning because it can cause injury or death to a developing fetus. Tell your provider right away if you become pregnant while taking it.

What should I avoid while taking this medication?

Avoid potassium supplements and salt substitutes containing potassium unless your provider approves them. Also tell your provider about NSAIDs (like ibuprofen) and lithium, which can interact with this medication.