Losartan-Hydrochlorothiazide 50-12.5 MG
Generic For: Hyzaar
Losartan-hydrochlorothiazide 50-12.5 mg (brand name Hyzaar) combines an angiotensin II receptor blocker with a thiazide diuretic in one tablet to treat high blood pressure. It is also used to lower the risk of stroke in certain patients with hypertension and left ventricular hypertrophy. After a licensed provider reviews your prescription, your order ships from a licensed U.S. pharmacy.
Compare all Losartan options →
Select Quantity *
90-day supply · $0.28/tablet
How It Works
- Select your medication
- Licensed providers review & prescribe
- Our licensed U.S. pharmacists fill your prescription
- Delivered to you as soon as the next day
Price: $25.00
HSA/FSA Eligible*Doctor visit fee & delivery cost not included in price. Refills at provider discretion.
Pharmacist Support
Fast Shipping
Licensed U.S. Pharmacy
Buy Losartan-Hydrochlorothiazide 50-12.5 MG Tablets Online
An angiotensin II receptor blocker and thiazide diuretic combination for high blood pressure and reducing stroke risk
Losartan-Hydrochlorothiazide 50-12.5 MG Quick Facts
| Drug class | ARB / thiazide diuretic combination |
|---|---|
| Treats | High blood pressure, stroke risk reduction in hypertension with LVH |
| Form | Tablet |
| Typical dosing | Take 1 tablet by mouth daily. |
| Prescription required | Yes — prescription only |
What Is Losartan-Hydrochlorothiazide 50-12.5 MG?
Losartan-hydrochlorothiazide 50-12.5 mg is a combination tablet containing losartan, an angiotensin II receptor blocker (ARB), and hydrochlorothiazide, a thiazide diuretic. Losartan relaxes blood vessels by blocking a hormone that narrows them, while hydrochlorothiazide helps the body eliminate excess salt and water. Together they lower blood pressure more effectively than either drug alone. It is sold under the brand name Hyzaar and requires a prescription.
What Does Losartan-Hydrochlorothiazide 50-12.5 MG Treat?
High blood pressure (hypertension)
Hypertension not adequately controlled on losartan or hydrochlorothiazide alone
Initial therapy for severe hypertension when rapid control is needed
Reduction of stroke risk in patients with hypertension and left ventricular hypertrophy
Losartan-Hydrochlorothiazide 50-12.5 MG Dosage
Take 1 tablet (50-12.5 mg) by mouth once daily.
May be titrated to 100-25 mg once daily based on blood pressure response after 3 weeks.
Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.
Losartan-Hydrochlorothiazide 50-12.5 MG Side Effects
Common side effects
- Dizziness
- Upper respiratory infection
- Back pain
- Fatigue
- Cough
- Increased urination
- Headache
Serious side effects
Stop taking this medication and seek medical attention right away if you experience:
- Fainting or severe lightheadedness (symptomatic hypotension)
- High potassium levels (hyperkalemia)
- Signs of kidney problems (decreased urination, swelling)
- Allergic reaction with swelling of face, lips, tongue, or throat (angioedema)
- Eye pain or vision changes (acute angle-closure glaucoma, myopia)
- Severe skin reactions
Warnings & Interactions
Do not use during pregnancy — can cause injury or death to a developing fetus
Contraindicated in patients with anuria or hypersensitivity to sulfonamide-derived drugs
Do not combine with aliskiren in patients with diabetes
May cause electrolyte imbalances — periodic monitoring recommended
Use caution with NSAIDs, lithium, and potassium supplements or potassium-sparing diuretics
May worsen kidney function in patients with renal artery stenosis or severe renal impairment
Can cause symptomatic low blood pressure, especially in volume-depleted patients
Tell your prescriber about all medications, supplements, and health conditions before starting losartan-hydrochlorothiazide 50-12.5 mg.
Talk to U.S.-Based Support
Our licensed pharmacy team in Boca Raton, Florida — real people, no overseas call centers.