Triamterne-Hydrochlorothiazide 37.5-25mg

Generic For: Dyazide / Maxzide

Triamterene-hydrochlorothiazide 37.5-25mg (Dyazide, Maxzide-25) is a combination diuretic tablet used to treat high blood pressure and edema in patients who develop low potassium on hydrochlorothiazide alone. It pairs a thiazide diuretic with a potassium-sparing diuretic to help the body remove excess fluid while limiting potassium loss. After a licensed provider reviews your prescription, your order ships from a licensed U.S. pharmacy.

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Buy Triamterene-Hydrochlorothiazide 37.5-25mg Online

A potassium-sparing diuretic combination for high blood pressure and edema (fluid retention)

Triamterne-Hydrochlorothiazide 37.5-25mg Quick Facts

Drug classPotassium-sparing diuretic combination
TreatsHigh blood pressure, edema (fluid retention)
FormTablet
Typical dosingTake 1 tablet by mouth daily.
Prescription requiredYes — prescription only

What Is Triamterne-Hydrochlorothiazide 37.5-25mg?

Triamterene-hydrochlorothiazide 37.5-25mg is a prescription tablet that combines two water pills: hydrochlorothiazide, a thiazide diuretic, and triamterene, a potassium-sparing diuretic. Hydrochlorothiazide helps the kidneys remove extra salt and water, which lowers blood pressure and reduces swelling. Triamterene helps offset the potassium loss that hydrochlorothiazide can cause. It is sold under the brand names Dyazide and Maxzide-25 and is intended for patients who become hypokalemic (low potassium) on hydrochlorothiazide alone.

What Does Triamterne-Hydrochlorothiazide 37.5-25mg Treat?

High blood pressure (hypertension) in patients who develop low potassium on hydrochlorothiazide alone
Edema (fluid retention) in patients who develop low potassium on hydrochlorothiazide alone
Hypertension when potassium supplementation is not desired or tolerated
Edema associated with heart failure, as directed by a provider
Edema associated with liver cirrhosis, as directed by a provider

Triamterne-Hydrochlorothiazide 37.5-25mg Dosage

Take 1 tablet (37.5-25mg) by mouth once daily.
May increase to 2 tablets once daily or 1 tablet twice daily as directed by your provider.
Maximum: 2 tablets (75-50mg total) per day.

Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.

Triamterne-Hydrochlorothiazide 37.5-25mg Side Effects

Common side effects

  • Dizziness or lightheadedness
  • Headache
  • Nausea or upset stomach
  • Dry mouth
  • Muscle cramps
  • Fatigue or weakness
  • Increased urination
  • Sensitivity to sunlight

Serious side effects

Stop taking this medication and seek medical attention right away if you experience:

  • Signs of high potassium (irregular heartbeat, muscle weakness, numbness or tingling)
  • Severe allergic reaction (rash, swelling of face or throat, trouble breathing)
  • Signs of dehydration or electrolyte imbalance (extreme thirst, confusion, fainting)
  • Unusual bleeding or bruising, or signs of infection
  • Severe skin reactions or blistering
  • Eye pain or sudden vision changes (possible acute glaucoma)

Warnings & Interactions

Do not use if you have high potassium (hyperkalemia) or are taking potassium supplements or other potassium-sparing diuretics
Contraindicated in anuria, significant kidney impairment, or sulfonamide allergy
Use caution with ACE inhibitors, ARBs, or NSAIDs — risk of high potassium and kidney injury
Lithium levels may rise; combination generally should be avoided
May worsen gout, diabetes, or lupus; monitor as directed
Electrolytes and kidney function should be checked periodically
Tell your provider if you are pregnant, planning pregnancy, or breastfeeding

Tell your prescriber about all medications, supplements, and health conditions before starting triamterne-hydrochlorothiazide 37.5-25mg.

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Frequently Asked Questions

What is triamterene-hydrochlorothiazide 37.5-25mg used for?

It is used to treat high blood pressure and edema (fluid retention) in patients who develop low potassium when taking hydrochlorothiazide alone. It combines two diuretics so the body can shed excess fluid while limiting potassium loss.

Do I need a prescription for triamterene-hydrochlorothiazide?

Yes. This medication is prescription-only in the United States. A licensed provider must review your health information and issue or verify a valid prescription before the pharmacy can dispense it.

How does ordering and shipping work?

After you place your order, a licensed provider reviews your prescription and medical details. Once approved, your medication is dispensed by a licensed U.S. pharmacy and shipped to your address; standard delivery times vary by location.

Is triamterene-hydrochlorothiazide the same as Dyazide or Maxzide?

Yes. Dyazide and Maxzide-25 are brand names for the 37.5-25mg strength of triamterene-hydrochlorothiazide. The generic contains the same active ingredients at the same strength.

How should I take triamterene-hydrochlorothiazide 37.5-25mg?

The typical adult dose is 1 tablet by mouth once daily, which your provider may adjust up to 2 tablets per day. Take it earlier in the day to reduce nighttime urination, and follow your provider's directions exactly.

Can I take potassium supplements with this medication?

Generally no. Because triamterene helps the body retain potassium, adding potassium supplements or salt substitutes containing potassium can raise potassium to dangerous levels. Discuss any supplements with your provider or pharmacist.

What should I avoid while taking this medication?

Avoid NSAIDs like ibuprofen unless your provider approves, limit alcohol, and use sun protection since the medication can increase sun sensitivity. Tell your provider about all medications you take, especially ACE inhibitors, ARBs, and lithium.