Triamterne-Hydrochlorothiazide 75-50mg

Generic For: Dyazide / Maxzide

Triamterene-hydrochlorothiazide 75-50mg (brand names Dyazide, Maxzide) is a prescription combination diuretic used to treat high blood pressure and edema in patients who develop low potassium on hydrochlorothiazide alone. After a licensed provider reviews your prescription, your order ships from a licensed U.S. pharmacy.

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A potassium-sparing diuretic combination for high blood pressure and fluid retention (edema)

Triamterne-Hydrochlorothiazide 75-50mg Quick Facts

Drug classPotassium-sparing diuretic combination
TreatsHigh blood pressure, edema (fluid retention)
FormTablet
Typical dosingTake 1 tablet by mouth daily.
Prescription requiredYes — prescription only

What Is Triamterne-Hydrochlorothiazide 75-50mg?

Triamterene-hydrochlorothiazide 75-50mg is a tablet that combines two diuretics (water pills) in one dose. Hydrochlorothiazide helps the body remove excess salt and water, which can lower blood pressure and reduce swelling, while triamterene helps the body retain potassium that thiazide diuretics can deplete. It is prescribed for people with hypertension or edema who develop low potassium (hypokalemia) on hydrochlorothiazide alone, or in whom low potassium cannot be risked. It is sold under the brand name Maxzide and is related to Dyazide, a lower-strength formulation.

What Does Triamterne-Hydrochlorothiazide 75-50mg Treat?

High blood pressure (hypertension)
Edema (fluid retention)
Hypertension in patients with thiazide-induced low potassium
Edema in patients who cannot risk hypokalemia
Adjunct to other antihypertensive medications

Triamterne-Hydrochlorothiazide 75-50mg Dosage

Hypertension or edema: 1 tablet (75-50mg) by mouth once daily.
Maximum: 1 tablet daily.

Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.

Triamterne-Hydrochlorothiazide 75-50mg Side Effects

Common side effects

  • Dizziness or lightheadedness
  • Headache
  • Nausea or upset stomach
  • Dry mouth
  • Increased urination
  • Muscle cramps
  • Fatigue or weakness

Serious side effects

Stop taking this medication and seek medical attention right away if you experience:

  • High potassium (hyperkalemia): irregular heartbeat, muscle weakness
  • Severe allergic reaction (rash, swelling, trouble breathing)
  • Signs of dehydration or electrolyte imbalance
  • Unusual bleeding or bruising
  • Severe dizziness or fainting
  • Signs of kidney problems (little or no urination)

Warnings & Interactions

Do not use with other potassium-sparing diuretics or potassium supplements
Contraindicated in anuria, significant kidney impairment, or hyperkalemia
Contraindicated with known sulfonamide or triamterene hypersensitivity
Use caution with ACE inhibitors, ARBs, and NSAIDs (hyperkalemia risk)
May increase lithium levels; avoid concurrent use
Monitor electrolytes and kidney function periodically
May cause photosensitivity; limit sun exposure

Tell your prescriber about all medications, supplements, and health conditions before starting triamterne-hydrochlorothiazide 75-50mg.

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Frequently Asked Questions

What is triamterene-hydrochlorothiazide 75-50mg used for?

It treats high blood pressure and edema (fluid retention) in patients who develop low potassium on hydrochlorothiazide alone. The combination helps remove excess fluid while preserving the body's potassium.

Is triamterene-hydrochlorothiazide the same as Dyazide or Maxzide?

Maxzide is the brand name for the 75-50mg tablet strength. Dyazide is a related lower-strength (37.5-25mg) capsule formulation; your prescriber will determine which strength is right for you.

Do I need a prescription for triamterene-hydrochlorothiazide?

Yes, this medication requires a valid prescription in the U.S. A licensed provider must review your health information and prescription before your order can be filled.

How does ordering and shipping work?

After you submit your prescription, a licensed pharmacist reviews it for accuracy and safety. Once approved, your medication ships directly from a licensed U.S. pharmacy to your address.

Can I take potassium supplements with this medication?

Generally no. Triamterene spares potassium, so adding supplements or salt substitutes containing potassium can lead to dangerously high potassium levels. Always confirm with your prescriber or pharmacist.

What should I do if I miss a dose?

Take it as soon as you remember, unless it is close to your next scheduled dose. Do not double up. Taking it earlier in the day can help avoid nighttime urination.

How should I store triamterene-hydrochlorothiazide tablets?

Store at room temperature, away from moisture, heat, and light. Keep the medication in its original container and out of reach of children.