Carbidopa Levodopa 25-100mg
Generic For: Sinemet
Carbidopa levodopa 25-100mg (brand name Sinemet) is a combination tablet used to treat the symptoms of Parkinson's disease and certain forms of parkinsonism. Levodopa is converted to dopamine in the brain, while carbidopa helps more levodopa reach the brain and reduces nausea. After a licensed provider reviews your prescription, your order ships from a licensed U.S. pharmacy.
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25-day supply · $0.30/tablet
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Buy Carbidopa Levodopa 25-100mg (Sinemet) Online
A dopamine precursor combination for Parkinson's disease and parkinsonism symptoms
Carbidopa Levodopa 25-100mg Quick Facts
| Drug class | Dopamine precursor combination |
|---|---|
| Treats | Parkinson's disease, post-encephalitic parkinsonism, symptomatic parkinsonism |
| Form | Tablet |
| Typical dosing | Take as directed by Primary Physician by mouth. |
| Prescription required | Yes — prescription only |
What Is Carbidopa Levodopa 25-100mg?
Carbidopa levodopa 25-100mg is a prescription tablet that combines two medicines to manage the symptoms of Parkinson's disease. Levodopa is converted into dopamine, a chemical messenger that is reduced in the brains of people with Parkinson's, helping improve movement, stiffness, and tremor. Carbidopa prevents levodopa from breaking down before it reaches the brain, which allows lower levodopa doses and fewer side effects like nausea. It is sold under the brand name Sinemet and as a generic.
What Does Carbidopa Levodopa 25-100mg Treat?
Parkinson's disease
Post-encephalitic parkinsonism
Parkinsonism following carbon monoxide intoxication
Parkinsonism following manganese intoxication
Carbidopa Levodopa 25-100mg Dosage
Initial: 1 tablet (25-100mg) by mouth 3 times daily.
May increase by 1 tablet daily or every other day as directed, up to a maximum of 8 tablets per day.
Take at evenly spaced intervals; follow your prescriber's individualized titration.
Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.
Carbidopa Levodopa 25-100mg Side Effects
Common side effects
- Nausea
- Dizziness
- Headache
- Drowsiness
- Dyskinesia (involuntary movements)
- Dry mouth
- Orthostatic hypotension (lightheadedness on standing)
- Insomnia
Serious side effects
Stop taking this medication and seek medical attention right away if you experience:
- Hallucinations or psychosis
- Sudden sleep onset during daily activities
- Severe or worsening dyskinesia
- Impulse control problems (gambling, compulsive behaviors)
- Depression with suicidal thoughts
- Symptoms resembling neuroleptic malignant syndrome if stopped abruptly (high fever, muscle rigidity)
Warnings & Interactions
Do not use with nonselective MAO inhibitors or within 14 days of stopping them
Contraindicated in narrow-angle glaucoma
Do not stop abruptly — risk of a syndrome resembling neuroleptic malignant syndrome
May cause sudden sleep episodes; use caution driving until effects are known
Use caution with a history of melanoma or undiagnosed skin lesions
May worsen symptoms in patients with cardiovascular disease or psychosis
High-protein meals and iron supplements can reduce levodopa absorption
Tell your prescriber about all medications, supplements, and health conditions before starting carbidopa levodopa 25-100mg.
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