Duloxetine 60mg

Generic For: Cymbalta

Duloxetine 60mg is the generic form of Cymbalta, a serotonin-norepinephrine reuptake inhibitor (SNRI) prescribed for major depressive disorder, generalized anxiety disorder, diabetic nerve pain, and fibromyalgia. If you're wondering where to buy duloxetine or how much duloxetine costs without insurance, our licensed U.S. pharmacy offers transparent pricing and ships directly to you after a licensed provider reviews your prescription.

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30-day supply · $0.83/capsule

How It Works

  1. Select your medication
  2. Licensed providers review & prescribe
  3. Our licensed U.S. pharmacists fill your prescription
  4. Delivered to you as soon as the next day

Price: $25.00

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*Doctor visit fee & delivery cost not included in price. Refills at provider discretion.

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Buy Duloxetine 60mg (Cymbalta) Online

An SNRI antidepressant for depression, anxiety, and nerve pain

Duloxetine 60mg Quick Facts

Drug classSNRI antidepressant
TreatsDepression, anxiety, diabetic nerve pain, fibromyalgia
FormCapsule
Typical dosingTake 1 capsule by mouth daily
Prescription requiredYes — prescription only

What Is Duloxetine 60mg?

Duloxetine is a prescription medication in the serotonin-norepinephrine reuptake inhibitor (SNRI) class, sold under the brand name Cymbalta. It works by increasing levels of serotonin and norepinephrine, chemicals in the brain that help regulate mood and dampen pain signals. It is FDA-approved to treat several conditions, including depression, anxiety, and certain types of chronic pain. Duloxetine is not available over the counter — a valid prescription from a licensed provider is required.

What Does Duloxetine 60mg Treat?

Major depressive disorder (MDD)
Generalized anxiety disorder (GAD)
Diabetic peripheral neuropathic pain
Fibromyalgia
Chronic musculoskeletal pain

Duloxetine 60mg Dosage

MDD: 40–60 mg by mouth daily (once daily or divided twice daily)
GAD, diabetic neuropathy, fibromyalgia, chronic musculoskeletal pain: 60 mg by mouth once daily
Some patients start at 30 mg once daily for 1 week before increasing to 60 mg; swallow capsules whole

Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.

Duloxetine 60mg Side Effects

Common side effects

  • Nausea
  • Dry mouth
  • Drowsiness or fatigue
  • Constipation
  • Decreased appetite
  • Increased sweating
  • Dizziness
  • Insomnia

Serious side effects

Stop taking this medication and seek medical attention right away if you experience:

  • Suicidal thoughts or behavior, especially in young adults
  • Signs of liver injury (dark urine, jaundice, abdominal pain)
  • Serotonin syndrome (agitation, fever, rapid heartbeat, muscle rigidity)
  • Severe skin reactions or allergic reactions
  • Unusual bleeding or bruising
  • Severe dizziness or fainting from low blood pressure

Warnings & Interactions

Boxed warning: increased risk of suicidal thoughts and behaviors in children, adolescents, and young adults
Do not use with MAO inhibitors or within 14 days of stopping one
Avoid in patients with substantial alcohol use or chronic liver disease
Risk of serotonin syndrome when combined with other serotonergic drugs (SSRIs, triptans, tramadol)
May increase bleeding risk, especially with NSAIDs, aspirin, or blood thinners
Do not stop abruptly — taper gradually to avoid discontinuation symptoms
Not recommended in uncontrolled narrow-angle glaucoma

Tell your prescriber about all medications, supplements, and health conditions before starting duloxetine 60mg.

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Frequently Asked Questions

How much does duloxetine cost without insurance?

As a widely available generic, duloxetine is typically affordable without insurance, often costing significantly less than brand-name Cymbalta. Exact pricing depends on the pharmacy, dose, and quantity — check our current price for duloxetine 60mg above.

How much does duloxetine 30 mg cost?

The 30 mg strength is usually priced similarly to or slightly less than the 60 mg capsules, since both are generic. Your provider will determine the right strength for you, and our pharmacy lists transparent pricing for each.

Can you buy duloxetine over the counter?

No. Duloxetine is a prescription-only medication in the United States and is not available over the counter. A licensed healthcare provider must evaluate whether it is appropriate and safe for you.

Where can I buy duloxetine?

Duloxetine is available at licensed pharmacies with a valid prescription. You can order it through our U.S.-licensed pharmacy online, and we'll coordinate with your prescriber if needed.

What is the prescription duloxetine used for?

Duloxetine is FDA-approved to treat major depressive disorder, generalized anxiety disorder, diabetic peripheral neuropathic pain, fibromyalgia, and chronic musculoskeletal pain. Your provider may prescribe it for one or more of these conditions.

Do I need a prescription to order duloxetine online?

Yes. Federal law requires a valid prescription for duloxetine. If you have one, you can transfer it to our pharmacy; a licensed provider or pharmacist reviews every order before it is filled.

How does ordering and shipping work?

Place your order online and submit or transfer your prescription. After a licensed provider reviews it, our U.S. pharmacy fills your order and ships it discreetly to your door, typically within a few business days.