Fosfomycin 3g

Generic For: Monurol

Fosfomycin 3g
Fosfomycin 3g — All Family Pharmacy
Fosfomycin 3g — All Family Pharmacy
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Fosfomycin (brand name Monurol) is a single-dose antibiotic supplied as 3g oral granules. It is FDA-approved to treat uncomplicated urinary tract infections (acute cystitis) in women caused by susceptible bacteria. After a licensed provider reviews your prescription, your order ships from a licensed U.S. pharmacy.

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Buy Fosfomycin 3g (Monurol) Online

Fosfomycin is a phosphonic acid antibiotic used to treat uncomplicated urinary tract infections (acute cystitis) in women

Medically reviewed by David Paul Mackarey, RPh, Pharmacist-in-Charge

Fosfomycin 3g Quick Facts

Drug classPhosphonic acid antibiotic
TreatsUncomplicated urinary tract infections, acute cystitis in women
FormGranules
Typical dosingEmpty 1 packet into 3-4 oz of cool water, stir until fully dissolved and drink entire mixture by mouth as a single dose. Do not take dry. Drink plenty of water after taking.
Prescription requiredYes — prescription only

What Is Fosfomycin 3g?

Fosfomycin, sold under the brand name Monurol, is an antibiotic that works by interfering with bacterial cell wall production. It is unique among UTI antibiotics because it is typically given as a single 3-gram dose of granules dissolved in water. It is FDA-approved for uncomplicated urinary tract infections (acute cystitis) in women caused by susceptible strains of Escherichia coli and Enterococcus faecalis. Fosfomycin is not indicated for kidney infections (pyelonephritis) or perinephric abscess.

What Does Fosfomycin 3g Treat?

Uncomplicated urinary tract infections (acute cystitis) in women
UTIs caused by susceptible Escherichia coli
UTIs caused by susceptible Enterococcus faecalis
Bladder infections confirmed or suspected by a healthcare provider

Fosfomycin 3g Dosage

Adult women: 3 g by mouth as a single dose
Dissolve one sachet of granules in 3–4 oz (90–120 mL) of cool water; drink immediately
Do not take with hot water; do not repeat dose without provider guidance

Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.

Fosfomycin 3g Side Effects

Common side effects

  • Diarrhea
  • Nausea
  • Headache
  • Dizziness
  • Vaginitis
  • Abdominal pain
  • Rhinitis
  • Weakness

Serious side effects

Stop taking this medication and seek medical attention right away if you experience:

  • Severe allergic reaction (rash, swelling, difficulty breathing)
  • Severe or persistent diarrhea (possible C. difficile-associated diarrhea)
  • Severe skin reactions
  • Angioedema
  • Worsening infection symptoms after treatment

Warnings & Interactions

Do not use if allergic to fosfomycin or any ingredient in Monurol
Not for pyelonephritis (kidney infection) or perinephric abscess
Do not take more than one single dose for one episode of cystitis
C. difficile-associated diarrhea has been reported; contact your provider if diarrhea develops
Metoclopramide may lower fosfomycin blood levels and effectiveness
Contact your provider if symptoms do not improve within 2–3 days
Tell your provider if you are pregnant or breastfeeding

Tell your prescriber about all medications, supplements, and health conditions before starting fosfomycin 3g.

Sources & References

  1. DailyMed – Monurol (fosfomycin tromethamine) granules
  2. MedlinePlus – Fosfomycin
  3. FDA – Drugs@FDA: Monurol

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Frequently Asked Questions

What is fosfomycin used for?

Fosfomycin (Monurol) is FDA-approved to treat uncomplicated urinary tract infections (acute cystitis) in women caused by susceptible strains of E. coli and Enterococcus faecalis. It is not used for kidney infections. Your provider will determine whether it is appropriate for your infection.

How do I take fosfomycin 3g granules?

Empty the entire contents of one sachet into 3–4 ounces of cool water, stir to dissolve, and drink immediately. Do not use hot water, and do not swallow the granules dry. It is usually taken as a single one-time dose.

How quickly does fosfomycin work?

Many people notice improvement in urinary symptoms within 2–3 days of the single dose. If your symptoms do not improve or they get worse, contact your healthcare provider, as a different treatment or further evaluation may be needed.

Do I need a prescription for fosfomycin?

Yes. Fosfomycin is a prescription-only medication in the United States. A licensed healthcare provider must evaluate your symptoms and issue a valid prescription before this medication can be dispensed.

How does ordering and shipping work?

After you place your order, a licensed provider or pharmacist reviews your prescription and health information. Once approved, your medication is dispensed and shipped from a licensed U.S. pharmacy to your address.

What are the most common side effects of fosfomycin?

The most common side effects include diarrhea, nausea, headache, dizziness, and vaginitis. Most are mild and short-lived. Seek medical attention for severe or persistent diarrhea or signs of an allergic reaction.

Can I take a second dose of fosfomycin if I still have symptoms?

No. Repeated doses do not improve outcomes for a single episode of cystitis and may increase side effects. If symptoms persist after 2–3 days, contact your healthcare provider for further evaluation.