Sulfamethoxazole/Trimethoprim 200mg/40mg
Generic For: Bactrim
Sulfamethoxazole/trimethoprim, sold under the brand name Bactrim, is a combination antibiotic used to treat urinary tract infections, acute exacerbations of chronic bronchitis, middle ear infections, and other bacterial infections. This 200mg/40mg per 5mL oral suspension requires a valid prescription. After review by a licensed provider, your medication ships directly from a licensed U.S. pharmacy.
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Sulfamethoxazole/trimethoprim (Bactrim) — a combination antibiotic for urinary tract infections, bronchitis, and ear infections
Sulfamethoxazole/Trimethoprim 200mg/40mg Quick Facts
| Drug class | Sulfonamide antibiotic combination |
|---|---|
| Treats | Urinary tract infections, bronchitis, ear infections, travelers' diarrhea |
| Form | Suspension |
| Typical dosing | Take 5-10mL by mouth daily as needed, or as directed by your Primary care doctor. Do not drink alcohol while taking this medication. |
| Prescription required | Yes — prescription only |
What Is Sulfamethoxazole/Trimethoprim 200mg/40mg?
Sulfamethoxazole/trimethoprim is a prescription antibiotic that combines two medicines — a sulfonamide and a folic acid synthesis inhibitor — that work together to stop the growth of susceptible bacteria. It is commonly known by the brand name Bactrim. This oral suspension contains 200mg of sulfamethoxazole and 40mg of trimethoprim per 5mL (one teaspoonful). It is used only for infections caused by bacteria and will not treat viral illnesses such as colds or the flu.
What Does Sulfamethoxazole/Trimethoprim 200mg/40mg Treat?
Urinary tract infections (UTIs)
Acute exacerbations of chronic bronchitis
Acute otitis media (middle ear infections) in children
Shigellosis (Shigella enteritis)
Travelers' diarrhea
Pneumocystis jirovecii pneumonia (treatment and prevention)
Sulfamethoxazole/Trimethoprim 200mg/40mg Dosage
UTI/shigellosis: 20 mL (800mg/160mg) by mouth every 12 hours for 10–14 days (5 days for shigellosis)
Acute exacerbations of chronic bronchitis: 20 mL by mouth every 12 hours for 14 days
Travelers' diarrhea: 20 mL by mouth every 12 hours for 5 days
Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.
Sulfamethoxazole/Trimethoprim 200mg/40mg Side Effects
Common side effects
- Nausea
- Vomiting
- Loss of appetite
- Skin rash
- Itching
- Diarrhea
- Headache
Serious side effects
Stop taking this medication and seek medical attention right away if you experience:
- Severe skin reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis)
- Signs of allergic reaction (swelling, difficulty breathing, hives)
- Unusual bruising or bleeding, or signs of low blood counts
- Severe or persistent diarrhea (possible C. difficile infection)
- Yellowing of the skin or eyes (liver problems)
- High potassium levels (irregular heartbeat, muscle weakness)
Warnings & Interactions
Do not use if allergic to sulfonamides or trimethoprim
Contraindicated in pregnancy at term, nursing mothers, and infants under 2 months
Avoid with a history of drug-induced immune thrombocytopenia from sulfonamides or trimethoprim
Use with caution in kidney or liver impairment; dose adjustment may be needed
May increase effects of warfarin, methotrexate, phenytoin, and certain diabetes medications
Can raise potassium levels, especially with ACE inhibitors, ARBs, or spironolactone
Drink plenty of fluids to reduce the risk of kidney stones (crystalluria)
Tell your prescriber about all medications, supplements, and health conditions before starting sulfamethoxazole/trimethoprim 200mg/40mg.
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