Hydroxyzine HCL 50mg
Generic For: Vistaril
Hydroxyzine HCL 50mg (brand name Vistaril) is a prescription antihistamine used to relieve anxiety and tension, calm itching caused by allergic skin conditions, and provide sedation before or after certain medical procedures. After a licensed provider reviews your prescription, your order ships from a licensed U.S. pharmacy.
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30-day supply · $0.33/tablet
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Buy Hydroxyzine HCL 50mg Online
An antihistamine tablet used for anxiety, itching from allergic skin conditions, and pre-procedure sedation
Hydroxyzine HCL 50mg Quick Facts
| Drug class | First-generation antihistamine |
|---|---|
| Treats | Anxiety, allergic itching (pruritus), pre-procedure sedation |
| Form | Tablet |
| Typical dosing | Take 1 tablet by mouth up to 3 times daily as needed for allergy symptoms or itching. |
| Prescription required | Yes — prescription only |
What Is Hydroxyzine HCL 50mg?
Hydroxyzine HCL is a first-generation antihistamine available under the brand name Vistaril. It works by blocking histamine, a natural substance involved in allergic reactions, and it also has calming effects on the central nervous system. Doctors prescribe hydroxyzine HCL for short-term relief of anxiety and tension, itching from allergic conditions such as hives and contact dermatitis, and as a sedative before or after anesthesia. It is available by prescription only in tablet form.
What Does Hydroxyzine HCL 50mg Treat?
Anxiety and tension (short-term symptomatic relief)
Itching (pruritus) from allergic conditions
Chronic hives (urticaria)
Atopic and contact dermatitis
Sedation before and after general anesthesia
Histamine-mediated pruritus
Hydroxyzine HCL 50mg Dosage
Anxiety: 50–100 mg by mouth 4 times daily.
Pruritus: 25 mg by mouth 3–4 times daily.
Pre/post-anesthesia sedation: 50–100 mg by mouth as a single dose.
Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.
Hydroxyzine HCL 50mg Side Effects
Common side effects
- Drowsiness
- Dry mouth
- Dizziness
- Headache
- Blurred vision
- Constipation
- Confusion (especially in older adults)
Serious side effects
Stop taking this medication and seek medical attention right away if you experience:
- Irregular or fast heartbeat (QT prolongation, torsade de pointes)
- Severe skin reactions (rash, blistering, pustules)
- Involuntary movements or tremor
- Seizures
- Signs of allergic reaction (swelling, difficulty breathing)
Warnings & Interactions
Do not use in early pregnancy; contraindicated in pregnancy per FDA labeling
Avoid alcohol and other CNS depressants; effects may be intensified
May cause QT prolongation; use caution with heart rhythm conditions or QT-prolonging drugs
Causes drowsiness; do not drive or operate machinery until you know how it affects you
Use caution in older adults due to increased sedation and anticholinergic effects
Contraindicated with known hypersensitivity to hydroxyzine or cetirizine
Tell your provider about all medications, including sedatives, opioids, and antidepressants
Tell your prescriber about all medications, supplements, and health conditions before starting hydroxyzine hcl 50mg.
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