Ibuprofen 800mg

Generic For: Motrin

Ibuprofen 800mg (brand name Motrin) is a prescription-strength nonsteroidal anti-inflammatory drug (NSAID) used to relieve mild to moderate pain and to reduce the pain, swelling, and stiffness of osteoarthritis and rheumatoid arthritis. It is also commonly prescribed alongside other medications — many patients ask whether they can take ibuprofen with amoxicillin or cyclobenzaprine, which a pharmacist can review with you. After a licensed provider reviews your information, your order ships from a licensed U.S. pharmacy.

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Buy Ibuprofen 800mg (Motrin) Online

Prescription-strength NSAID for pain, arthritis, and menstrual cramps

Ibuprofen 800mg Quick Facts

Drug classNonsteroidal anti-inflammatory drug (NSAID)
TreatsPain, osteoarthritis, rheumatoid arthritis, menstrual cramps
FormTablet
Typical dosingTake 1 tablet by mouth every 8 hours as needed for pain.
Prescription requiredYes — prescription only

What Is Ibuprofen 800mg?

Ibuprofen 800mg is the highest prescription-strength tablet of ibuprofen, an NSAID that works by reducing substances in the body that cause pain and inflammation. Unlike lower-dose over-the-counter versions, the 800mg tablet requires a prescription and provider oversight. It is FDA-approved to relieve mild to moderate pain, the signs and symptoms of osteoarthritis and rheumatoid arthritis, and primary dysmenorrhea (menstrual cramps). Because it is often used together with antibiotics like amoxicillin or muscle relaxants like cyclobenzaprine, it's important to review your full medication list with your provider or pharmacist.

What Does Ibuprofen 800mg Treat?

Mild to moderate pain
Osteoarthritis
Rheumatoid arthritis
Primary dysmenorrhea (menstrual cramps)
Inflammation and swelling
Fever reduction (when directed by a provider)

Ibuprofen 800mg Dosage

Pain/dysmenorrhea: 400 mg by mouth every 4–6 hours as needed
Osteoarthritis/rheumatoid arthritis: 400–800 mg by mouth 3–4 times daily; max 3200 mg/day
Use the lowest effective dose for the shortest duration needed

Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.

Ibuprofen 800mg Side Effects

Common side effects

  • Upset stomach or heartburn
  • Nausea
  • Dizziness
  • Headache
  • Gas or bloating
  • Constipation or diarrhea
  • Mild rash

Serious side effects

Stop taking this medication and seek medical attention right away if you experience:

  • Signs of stomach bleeding (black stools, vomiting blood)
  • Chest pain, shortness of breath, or stroke symptoms
  • Swelling of the face, lips, or throat (allergic reaction)
  • Unexplained weight gain or swelling of legs/ankles
  • Severe skin reactions (blistering, peeling rash)
  • Decreased urination or signs of kidney problems

Warnings & Interactions

Boxed warning: increased risk of heart attack, stroke, and serious GI bleeding
Do not use right before or after heart bypass (CABG) surgery
Avoid if allergic to aspirin or other NSAIDs
Avoid during the last trimester of pregnancy (about 20 weeks and later, per FDA)
Use caution with blood thinners, aspirin, corticosteroids, and other NSAIDs
May reduce the effect of some blood pressure medicines; can affect kidney function
Avoid or limit alcohol, which raises the risk of stomach bleeding

Tell your prescriber about all medications, supplements, and health conditions before starting ibuprofen 800mg.

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Frequently Asked Questions

Can you take ibuprofen with amoxicillin?

Ibuprofen and amoxicillin have no known major interaction and are often taken together, for example for pain or fever during an infection. This also applies to common strengths like amoxicillin 500mg. Always confirm with your provider or pharmacist, since your health history and other medications matter.

Can I take cyclobenzaprine with ibuprofen?

Cyclobenzaprine and ibuprofen are frequently prescribed together for muscle-related pain, and there is no known major interaction between them. Cyclobenzaprine can cause drowsiness on its own, so avoid alcohol and use caution when driving. Check with your provider before combining any medications.

Can you take cephalexin and ibuprofen together?

Cephalexin and ibuprofen have no known major interaction and can generally be taken together when both are prescribed. Tell your provider about all medicines you take, especially if you have kidney problems, since both drugs are processed by the kidneys.

Do I need a prescription for Ibuprofen 800mg?

Yes. While lower-dose ibuprofen (200mg) is available over the counter, the 800mg tablet is prescription-only in the U.S. A licensed provider must review your health information and approve the prescription before it can be dispensed.

How does ordering and shipping work?

After you place your order and complete a brief health questionnaire, a licensed provider reviews your information. If a prescription is appropriate, it is filled and shipped from a licensed U.S. pharmacy, or we can fill a valid prescription from your own doctor.

What is the difference between Ibuprofen 800mg and Motrin?

Motrin is a brand name for ibuprofen; the generic contains the same active ingredient at the same strength. Generic ibuprofen 800mg is FDA-approved and typically costs less than the brand version.