Ibuprofen/Famotidine 800mg/26.6mg

Generic For: Duexis

Ibuprofen/famotidine 800mg/26.6mg (brand name Duexis) combines an NSAID pain reliever with an acid reducer in a single tablet. It is prescribed to relieve symptoms of rheumatoid arthritis and osteoarthritis while reducing the risk of ibuprofen-related stomach ulcers. After a licensed provider reviews your order, your medication ships from a licensed U.S. pharmacy.

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Buy Ibuprofen/Famotidine 800mg/26.6mg (Duexis) Online

An NSAID and acid reducer combination for rheumatoid arthritis, osteoarthritis, and stomach ulcer prevention

Ibuprofen/Famotidine 800mg/26.6mg Quick Facts

Drug classNSAID / H2-blocker combination
TreatsRheumatoid arthritis, osteoarthritis, ulcer risk reduction
FormTablet
Typical dosingTake 1 tablet by mouth 3 times daily as needed for pain.
Prescription requiredYes — prescription only

What Is Ibuprofen/Famotidine 800mg/26.6mg?

Ibuprofen/famotidine is a fixed-dose combination tablet containing 800mg of ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID), and 26.6mg of famotidine, a histamine H2-receptor blocker. The ibuprofen component relieves pain, swelling, and stiffness from arthritis, while the famotidine component reduces stomach acid to lower the chance of developing ulcers in the stomach or upper intestine — a known risk of long-term NSAID use. It is sold under the brand name Duexis and is available by prescription only. It is intended for patients who need ibuprofen for arthritis and are at risk for NSAID-associated ulcers.

What Does Ibuprofen/Famotidine 800mg/26.6mg Treat?

Relief of signs and symptoms of rheumatoid arthritis
Relief of signs and symptoms of osteoarthritis
Reduced risk of upper gastrointestinal ulcers in patients taking ibuprofen
Management of arthritis pain, swelling, and stiffness

Ibuprofen/Famotidine 800mg/26.6mg Dosage

1 tablet (800mg/26.6mg) by mouth three times daily.
Use the lowest effective duration consistent with treatment goals.
Do not split, chew, or divide tablets.

Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.

Ibuprofen/Famotidine 800mg/26.6mg Side Effects

Common side effects

  • Nausea
  • Diarrhea
  • Constipation
  • Upper abdominal pain
  • Headache
  • Heartburn
  • Upper respiratory infection symptoms

Serious side effects

Stop taking this medication and seek medical attention right away if you experience:

  • Chest pain, weakness, or slurred speech (signs of heart attack or stroke)
  • Black, tarry stools or vomiting blood (GI bleeding)
  • Swelling, rapid weight gain, or reduced urination (kidney problems)
  • Yellowing of skin or eyes (liver problems)
  • Severe skin rash, blistering, or peeling
  • Difficulty breathing or facial swelling (allergic reaction)

Warnings & Interactions

Boxed warning: increased risk of serious cardiovascular events, including heart attack and stroke
Boxed warning: increased risk of serious GI bleeding, ulceration, and perforation
Do not use for pain around the time of coronary artery bypass graft (CABG) surgery
Contraindicated with history of asthma, urticaria, or allergic reaction to aspirin or other NSAIDs
Avoid in late pregnancy (30 weeks and later); may harm the fetus
Use caution with anticoagulants, aspirin, ACE inhibitors, diuretics, and lithium
Avoid in patients with severe renal impairment or advanced kidney disease

Tell your prescriber about all medications, supplements, and health conditions before starting ibuprofen/famotidine 800mg/26.6mg.

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Frequently Asked Questions

What is ibuprofen/famotidine?

Ibuprofen/famotidine is a prescription combination tablet sold under the brand name Duexis. It pairs the NSAID ibuprofen, which relieves arthritis pain and inflammation, with famotidine, an acid reducer that lowers the risk of stomach ulcers linked to NSAID use.

Do I need a prescription for ibuprofen/famotidine 800mg/26.6mg?

Yes, this medication requires a prescription in the United States. A licensed healthcare provider must review your health information and determine that it is appropriate for you before it can be dispensed.

How does ordering and shipping work?

After you place your order, a licensed provider reviews your health information and, if appropriate, issues or verifies a prescription. Your medication is then filled and shipped directly to you from a licensed U.S. pharmacy.

Why is famotidine combined with ibuprofen?

Long-term use of NSAIDs like ibuprofen can increase the risk of ulcers in the stomach and upper intestine. Famotidine reduces stomach acid, which helps lower that ulcer risk in patients who need ongoing ibuprofen therapy.

Can I take extra ibuprofen with this medication?

No, you should not take additional ibuprofen or other NSAIDs unless your provider directs you to. Each tablet already contains a full 800mg dose of ibuprofen, and extra NSAIDs raise the risk of serious side effects.

What should I tell my provider before taking ibuprofen/famotidine?

Tell your provider about any history of heart disease, stroke, stomach ulcers or bleeding, kidney or liver problems, asthma, or allergic reactions to aspirin or NSAIDs. Also list all medications you take, including blood thinners, aspirin, blood pressure medicines, and diuretics.