Indomethacin 50 mg

Generic For: Indocin

Indomethacin (brand name Indocin) is a prescription nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain, swelling, and stiffness caused by arthritis, gout flares, and other inflammatory conditions. After a licensed provider reviews your information and confirms a valid prescription, your indomethacin 50 mg capsules ship discreetly from a licensed U.S. pharmacy.

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Buy Indomethacin 50 mg Capsules Online

A prescription NSAID for arthritis, gout, and ankylosing spondylitis

Indomethacin 50 mg Quick Facts

Drug classNonsteroidal anti-inflammatory drug (NSAID)
TreatsRheumatoid arthritis, osteoarthritis, gout flares, ankylosing spondylitis
FormCapsule
Typical dosingTake 1 capsule by mouth every 8 hours as needed for pain. No more than 3 capsules in 24 hours.
Prescription requiredYes — prescription only

What Is Indomethacin 50 mg?

Indomethacin is a nonsteroidal anti-inflammatory drug (NSAID) available under the brand name Indocin. It works by reducing substances in the body that cause inflammation, pain, and fever. Doctors prescribe indomethacin for moderate to severe arthritis conditions, acute gout attacks, and painful shoulder problems such as bursitis or tendinitis. Because it is a potent NSAID, it requires a prescription and monitoring by a healthcare provider.

What Does Indomethacin 50 mg Treat?

Moderate to severe rheumatoid arthritis
Moderate to severe osteoarthritis
Moderate to severe ankylosing spondylitis
Acute gouty arthritis (gout flares)
Acute painful shoulder (bursitis and/or tendinitis)

Indomethacin 50 mg Dosage

Arthritis: 25 mg by mouth 2-3 times daily; may increase by 25-50 mg/day as needed; max 200 mg/day.
Acute gout: 50 mg by mouth 3 times daily until pain is tolerable, then rapidly taper and discontinue.
Acute painful shoulder: 75-150 mg/day by mouth in 3-4 divided doses for 7-14 days.

Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.

Indomethacin 50 mg Side Effects

Common side effects

  • Headache
  • Dizziness
  • Nausea
  • Heartburn or indigestion
  • Stomach pain
  • Constipation or diarrhea
  • Drowsiness or fatigue
  • Ringing in the ears (tinnitus)

Serious side effects

Stop taking this medication and seek medical attention right away if you experience:

  • Signs of stomach or intestinal bleeding (black stools, vomiting blood)
  • Chest pain, weakness, or slurred speech (possible heart attack or stroke)
  • Swelling, rapid weight gain, or decreased urination (kidney problems)
  • Severe skin reactions (rash, blistering, peeling)
  • Yellowing of the skin or eyes (liver problems)
  • Severe allergic reaction (swelling of face or throat, trouble breathing)

Warnings & Interactions

Boxed warning: increased risk of serious cardiovascular events (heart attack, stroke)
Boxed warning: risk of serious GI bleeding, ulceration, and perforation, which can be fatal
Do not use for pain right before or after coronary artery bypass graft (CABG) surgery
Avoid in patients with aspirin-sensitive asthma or prior allergic reaction to NSAIDs
Avoid use at 20 weeks of pregnancy and later
Use caution with blood thinners, aspirin, corticosteroids, SSRIs, lithium, and methotrexate
May worsen high blood pressure, heart failure, or kidney disease

Tell your prescriber about all medications, supplements, and health conditions before starting indomethacin 50 mg.

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Frequently Asked Questions

What is indomethacin used for?

Indomethacin is an NSAID prescribed for moderate to severe rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis, as well as acute gout flares and painful shoulder conditions like bursitis or tendinitis. It reduces pain, swelling, and stiffness caused by inflammation.

Do I need a prescription for indomethacin?

Yes. Indomethacin is a prescription-only medication in the United States. A licensed provider must review your health history and issue a valid prescription before it can be dispensed.

How does ordering and shipping work?

After you place your order, a licensed healthcare provider reviews your information and prescription. Once approved, your medication is filled and shipped from a licensed U.S. pharmacy in discreet packaging.

How quickly does indomethacin work for gout?

Many people notice pain relief within hours to a couple of days when treating an acute gout flare, though individual responses vary. For gout, it is typically taken only until the flare resolves, then tapered and stopped as directed by your provider.

Can I take indomethacin with food?

Yes, taking indomethacin with food, milk, or an antacid may help reduce stomach upset. Follow your prescriber's instructions and never exceed the prescribed dose.

What should I avoid while taking indomethacin?

Avoid alcohol and other NSAIDs (such as ibuprofen or naproxen), which raise the risk of stomach bleeding. Tell your provider about all medications you take, especially blood thinners, aspirin, steroids, lithium, and methotrexate.

Is indomethacin the same as Indocin?

Yes. Indocin is the brand name for indomethacin. The generic capsules contain the same active ingredient and are held to the same FDA standards.