Levothyroxine 25mcg
Generic For: Synthroid
Levothyroxine 25mcg (brand name Synthroid) is a synthetic thyroid hormone tablet used to treat hypothyroidism and certain other thyroid conditions. It replaces the hormone your thyroid gland is not producing enough of on its own. After a licensed provider reviews your prescription, your order ships from a licensed U.S. pharmacy.
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90-day supply · $0.28/tablet
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Levothyroxine is a thyroid hormone replacement used for hypothyroidism, goiter, and thyroid cancer management
Levothyroxine 25mcg Quick Facts
| Drug class | Thyroid hormone replacement |
|---|---|
| Treats | Hypothyroidism, goiter, thyroid cancer (adjunct) |
| Form | Tablet |
| Typical dosing | Take 1 tablet by mouth daily in the morning. |
| Prescription required | Yes — prescription only |
What Is Levothyroxine 25mcg?
Levothyroxine is a man-made version of thyroxine (T4), a hormone naturally produced by the thyroid gland. When the thyroid does not make enough hormone, symptoms such as fatigue, weight gain, cold intolerance, and dry skin can develop. Taking levothyroxine daily restores normal hormone levels, and most people take it long term under a provider's supervision. The 25mcg strength is a lower dose often used when starting treatment or fine-tuning therapy based on lab results.
What Does Levothyroxine 25mcg Treat?
Primary hypothyroidism
Secondary (pituitary) hypothyroidism
Tertiary (hypothalamic) hypothyroidism
Congenital hypothyroidism
TSH suppression in well-differentiated thyroid cancer (adjunct)
Pituitary TSH suppression for certain goiters
Levothyroxine 25mcg Dosage
Adults with hypothyroidism: approximately 1.6 mcg/kg by mouth once daily.
Take on an empty stomach, 30–60 minutes before breakfast.
Dose is individualized and adjusted every 4–6 weeks based on TSH levels.
Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.
Levothyroxine 25mcg Side Effects
Common side effects
- Hair loss (usually temporary, early in treatment)
- Headache
- Nervousness or irritability
- Trouble sleeping
- Increased sweating
- Changes in appetite or weight
- Diarrhea
- Menstrual changes
Serious side effects
Stop taking this medication and seek medical attention right away if you experience:
- Chest pain or rapid, irregular heartbeat
- Signs of allergic reaction (rash, swelling, trouble breathing)
- Severe anxiety, tremor, or heat intolerance (possible overtreatment)
- Seizures
- Bone pain or fracture (long-term high doses)
Warnings & Interactions
Not for weight loss; large doses can cause serious or life-threatening effects (boxed warning)
Do not use with uncorrected adrenal insufficiency
Use caution in patients with heart disease; may worsen angina or arrhythmias
May affect blood sugar control in diabetes and increase warfarin's effect
Take 4 hours apart from calcium, iron, antacids, and certain cholesterol binders
Long-term overtreatment may decrease bone mineral density
Dose needs often change during pregnancy; tell your provider if pregnant
Tell your prescriber about all medications, supplements, and health conditions before starting levothyroxine 25mcg.
Sources & References
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