Metronidazole 500mg

Generic For: Flagyl

Metronidazole 500mg (brand name Flagyl) is a prescription nitroimidazole antibiotic used to treat trichomoniasis, amebiasis, and serious infections caused by anaerobic bacteria. It is sometimes prescribed alongside other antibiotics, such as amoxicillin, when a provider determines combination therapy is appropriate. After review of your prescription by a licensed provider, your order ships from a licensed U.S. pharmacy.

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Buy Metronidazole 500mg (Flagyl) Online

A nitroimidazole antibiotic for trichomoniasis, amebiasis, and anaerobic bacterial infections

Metronidazole 500mg Quick Facts

Drug classNitroimidazole antibiotic
TreatsTrichomoniasis, amebiasis, anaerobic bacterial infections
FormTablet
Typical dosingTake 1 tablet by mouth twice daily for 10 days. Do not drink alcohol while taking this medication.
Prescription requiredYes — prescription only

What Is Metronidazole 500mg?

Metronidazole is a nitroimidazole antibiotic sold under the brand name Flagyl. It works by disrupting the DNA of susceptible bacteria and parasites, stopping the infection from spreading. It is FDA-approved to treat trichomoniasis, intestinal and liver amebiasis, and a range of serious anaerobic bacterial infections. Because it targets different organisms than penicillin-class drugs, providers sometimes prescribe metronidazole together with amoxicillin for certain infections, such as dental abscesses.

What Does Metronidazole 500mg Treat?

Trichomoniasis (in patients and their partners)
Intestinal amebiasis (amebic dysentery)
Amebic liver abscess
Intra-abdominal anaerobic bacterial infections
Skin and skin structure anaerobic infections
Gynecologic anaerobic infections
Anaerobic bone, joint, CNS, and lower respiratory infections

Metronidazole 500mg Dosage

Trichomoniasis: 2 g by mouth as a single dose, or 500 mg by mouth twice daily for 7 days
Amebiasis: 750 mg by mouth three times daily for 5–10 days
Anaerobic infections: 7.5 mg/kg by mouth every 6 hours (usual adult dose 500 mg), not to exceed 4 g/day, for 7–10 days

Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.

Metronidazole 500mg Side Effects

Common side effects

  • Nausea
  • Headache
  • Metallic taste in the mouth
  • Loss of appetite
  • Diarrhea
  • Dizziness
  • Abdominal cramping
  • Dark-colored urine

Serious side effects

Stop taking this medication and seek medical attention right away if you experience:

  • Seizures
  • Numbness or tingling in hands or feet (peripheral neuropathy)
  • Severe allergic reaction (rash, swelling, difficulty breathing)
  • Encephalopathy (confusion, trouble speaking, coordination problems)
  • Aseptic meningitis (severe headache, stiff neck, fever)
  • Severe skin reactions (blistering, peeling)

Warnings & Interactions

Boxed warning: metronidazole was carcinogenic in animal studies; use only for approved indications
Do not drink alcohol during treatment and for at least 3 days after the last dose
Contraindicated with disulfiram use within the past 2 weeks
Contraindicated in the first trimester of pregnancy for trichomoniasis
May increase the effects of warfarin and other blood thinners
Stop and seek care if neurologic symptoms (numbness, seizures, confusion) develop
Use with caution in severe liver disease; contraindicated in Cockayne syndrome

Tell your prescriber about all medications, supplements, and health conditions before starting metronidazole 500mg.

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Frequently Asked Questions

Can you take amoxicillin and metronidazole together?

Yes, providers sometimes prescribe amoxicillin and metronidazole together because they target different types of bacteria — for example, in certain dental or intra-abdominal infections. Only take both if your prescriber has specifically directed the combination. Follow your provider's instructions for dose and duration.

Do I need a prescription for metronidazole 500mg?

Yes. Metronidazole is a prescription-only medication in the United States. A licensed provider must review your prescription before our pharmacy can dispense it.

How does ordering and shipping work?

Submit your prescription (or have your provider send it to us), and a licensed pharmacist reviews the order before it is filled. Once approved, your medication ships from a licensed U.S. pharmacy in discreet packaging. Contact us if you have questions about delivery timing.

Can I drink alcohol while taking metronidazole?

No. Combining alcohol with metronidazole can cause flushing, nausea, vomiting, cramping, and headache. Avoid alcohol during treatment and for at least 3 days after your last dose.

What is metronidazole 500mg used for?

Metronidazole is FDA-approved to treat trichomoniasis, intestinal and liver amebiasis, and serious infections caused by anaerobic bacteria. Your provider will determine whether it is appropriate for your specific infection.

What are the most common side effects?

The most common side effects include nausea, headache, a metallic taste, loss of appetite, and dizziness. Contact your provider if you experience numbness, tingling, seizures, confusion, or signs of an allergic reaction.

Is Flagyl the same as metronidazole?

Yes. Flagyl is the brand name for metronidazole. Both contain the same active ingredient and are held to the same FDA standards.