What is naltrexone used for?

Naltrexone is FDA-approved to treat alcohol use disorder and to help prevent relapse to opioid dependence after detoxification. At low doses such as 1mg, it is sometimes prescribed off-label for chronic pain and certain inflammatory conditions.

What is Low Dose Naltrexone (LDN)?

Low Dose Naltrexone refers to naltrexone taken at much smaller doses (typically 1–4.5 mg) than the standard 50 mg dose. This use is off-label, meaning it is not FDA-approved, and should only be taken under the direction of a licensed prescriber.

Do I need a prescription for naltrexone?

Yes. Naltrexone is a prescription-only medication in the United States. A licensed healthcare provider must evaluate whether it is appropriate for you before it can be dispensed.

How does ordering and shipping work?

After you submit your prescription or complete a provider consultation, a licensed clinician reviews your information. Once approved, your medication is dispensed and shipped from a licensed U.S. pharmacy directly to your address.

Can I take naltrexone if I am taking opioid pain medication?

No. Naltrexone blocks opioid receptors and can trigger sudden, severe withdrawal in people who are physically dependent on opioids. You typically need to be opioid-free for 7–10 days before starting; discuss timing with your provider.

What are the most common side effects of naltrexone?

Common side effects include nausea, headache, dizziness, fatigue, and trouble sleeping. Many effects lessen over time, but contact your provider if symptoms persist or you notice signs of liver problems.

Is naltrexone addictive?

No. Naltrexone is not an opioid, is not habit-forming, and does not cause physical dependence. It works by blocking opioid receptors rather than activating them.

Naltrexone 1mg

Name: Naltrexone 1mg
Brand: All Family Pharmacy
SKU: naltrexone-1mg
Availability: InStock

Generic For: Low Dose Naltrexone

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Naltrexone is an opioid antagonist that blocks the effects of opioids and helps reduce alcohol cravings. FDA-approved for alcohol use disorder and to prevent relapse to opioid dependence, it is also prescribed at low doses (such as 1mg) off-label for certain chronic conditions. After a licensed provider reviews your prescription, your order ships from a licensed U.S. pharmacy.

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Buy Naltrexone 1mg (Low Dose Naltrexone) Online

Naltrexone is an opioid antagonist used for alcohol use disorder and opioid dependence; low-dose naltrexone is prescribed off-label for chronic pain and inflammatory conditions.

Medically reviewed by David Paul Mackarey, RPh, Pharmacist-in-Charge

Naltrexone 1mg Quick Facts

Drug class	Opioid antagonist
Treats	Alcohol use disorder, opioid dependence, chronic pain (off-label)
Form	Capsule
Typical dosing	Take 1 capsule by mouth daily
Prescription required	Yes — prescription only

What Is Naltrexone 1mg?

Naltrexone is a prescription medication in the opioid antagonist class. It works by blocking opioid receptors in the brain, which reduces the rewarding effects of alcohol and opioids. At standard doses, naltrexone is FDA-approved to treat alcohol use disorder and to help prevent relapse in people who have stopped using opioids. Low Dose Naltrexone (LDN), such as this 1mg capsule, is prescribed off-label by some providers for conditions involving chronic pain or inflammation.

What Does Naltrexone 1mg Treat?

Alcohol use disorder
Blockade of the effects of opioids
Prevention of relapse to opioid dependence after detoxification
Chronic pain (off-label, low-dose)
Fibromyalgia (off-label, low-dose)
Inflammatory and autoimmune conditions (off-label, low-dose)

Naltrexone 1mg Dosage

Alcohol use disorder: 50 mg by mouth once daily (per FDA labeling).
Opioid dependence: 50 mg by mouth once daily after opioid-free period of 7–10 days.
Low-dose regimens (e.g., 1–4.5 mg once daily) are off-label; follow your prescriber's directions.

Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.

Naltrexone 1mg Side Effects

Common side effects

Nausea
Headache
Dizziness
Fatigue
Insomnia or vivid dreams
Anxiety or nervousness
Abdominal pain or cramps
Joint or muscle pain

Serious side effects

Stop taking this medication and seek medical attention right away if you experience:

Signs of liver injury (dark urine, yellowing skin or eyes, severe stomach pain)
Severe allergic reaction (rash, swelling, difficulty breathing)
Depression or suicidal thoughts
Precipitated opioid withdrawal (sweating, agitation, vomiting)
Severe injection-site or skin reactions

Warnings & Interactions

Do not use if currently taking opioids or in acute opioid withdrawal
Requires an opioid-free period (typically 7–10 days) before starting for opioid dependence
Blocks opioid pain medications; opioid overdose risk increases if opioids are used to overcome the blockade
Can cause liver injury; use caution in liver disease and report symptoms promptly
Contraindicated with known hypersensitivity to naltrexone
Tell your provider about all medications, including opioid-containing cough or diarrhea medicines
Monitor for depression or mood changes

Tell your prescriber about all medications, supplements, and health conditions before starting naltrexone 1mg.