Naltrexone 3mg

Generic For: Low Dose Naltrexone

Naltrexone is an opioid antagonist that is FDA-approved to treat alcohol use disorder and to help prevent relapse to opioid dependence. Naltrexone 3mg capsules, commonly called low dose naltrexone (LDN), are a compounded low-dose form prescribed off-label by some providers for conditions such as chronic pain and fibromyalgia. Your order ships from a licensed U.S. pharmacy after review of your valid prescription by a licensed provider.

Select Quantity *

30-day supply · $1.50/capsule

How It Works

  1. Select your medication
  2. Licensed providers review & prescribe
  3. Our licensed U.S. pharmacists fill your prescription
  4. Delivered to you as soon as the next day

Price: $45.00

HSA/FSA Eligible
Get Started

*Doctor visit fee & delivery cost not included in price. Refills at provider discretion.

Pharmacist Support Fast Shipping Licensed U.S. Pharmacy

Buy Naltrexone 3mg (Low Dose Naltrexone) Online

An opioid antagonist used for alcohol use disorder, opioid dependence, and — at low doses — off-label support for chronic pain and inflammatory conditions

Naltrexone 3mg Quick Facts

Drug classOpioid antagonist
TreatsAlcohol use disorder, opioid dependence (relapse prevention), off-label chronic pain (low dose)
FormCapsule
Typical dosingTake 1 capsule by mouth daily
Prescription requiredYes — prescription only

What Is Naltrexone 3mg?

Naltrexone is a prescription medication that blocks opioid receptors in the brain. At its standard FDA-approved strength (50mg), it is used to treat alcohol use disorder and to block the effects of opioids in people who have completed opioid detoxification. Naltrexone 3mg, known as low dose naltrexone (LDN), is a compounded capsule prescribed off-label; some providers use it for chronic pain, fibromyalgia, and certain inflammatory conditions, though these uses are not FDA-approved. It is not an opioid, is not addictive, and does not cause physical dependence.

What Does Naltrexone 3mg Treat?

Alcohol use disorder (FDA-approved, standard dose)
Prevention of relapse to opioid dependence after detoxification (FDA-approved, standard dose)
Blockade of the effects of exogenous opioids (FDA-approved, standard dose)
Chronic pain (off-label, low dose)
Fibromyalgia (off-label, low dose)
Certain inflammatory and autoimmune conditions (off-label, low dose)

Naltrexone 3mg Dosage

FDA-approved (naltrexone 50mg tablets): 50 mg by mouth once daily.
Low dose naltrexone 3mg (compounded, off-label): typically 1 capsule (3 mg) by mouth once daily, often at bedtime, exactly as prescribed.
Take only as directed by your prescriber.

Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.

Naltrexone 3mg Side Effects

Common side effects

  • Nausea
  • Headache
  • Dizziness
  • Insomnia or vivid dreams
  • Fatigue
  • Anxiety or nervousness
  • Abdominal pain or cramps
  • Joint or muscle aches

Serious side effects

Stop taking this medication and seek medical attention right away if you experience:

  • Signs of liver injury (dark urine, yellowing of skin or eyes, severe abdominal pain)
  • Severe allergic reaction (rash, swelling, difficulty breathing)
  • Depression or suicidal thoughts
  • Severe injection-site or skin reactions
  • Precipitated opioid withdrawal (agitation, sweating, vomiting) if opioids are in your system

Warnings & Interactions

Do not use if currently taking opioids or in acute opioid withdrawal — can cause sudden, severe withdrawal
Do not use with opioid-containing medicines, including some cough, cold, and anti-diarrheal products
Opioid pain medicines will not work while taking naltrexone; attempting to overcome the blockade can cause fatal overdose
Risk of opioid overdose after stopping naltrexone due to reduced opioid tolerance
Use with caution in liver or kidney disease; liver injury has been reported
Tell your provider if you are pregnant, planning pregnancy, or breastfeeding
Carry medical identification noting that you take naltrexone

Tell your prescriber about all medications, supplements, and health conditions before starting naltrexone 3mg.

Talk to U.S.-Based Support

Our licensed pharmacy team in Boca Raton, Florida — real people, no overseas call centers.

Frequently Asked Questions

What is naltrexone used for?

Naltrexone is FDA-approved at standard doses (50mg) to treat alcohol use disorder and to help prevent relapse to opioid dependence after detoxification. The 3mg strength, called low dose naltrexone (LDN), is a compounded form some providers prescribe off-label for conditions like chronic pain and fibromyalgia.

What is low dose naltrexone (LDN)?

Low dose naltrexone refers to compounded naltrexone at doses far below the standard 50mg, typically 0.5–4.5 mg daily. Its off-label uses are being studied but are not FDA-approved, so it should be taken only under the guidance of a licensed provider.

Do I need a prescription for naltrexone 3mg?

Yes. Naltrexone is a prescription-only medication in the United States. A licensed provider must review your health history and issue a valid prescription before this pharmacy can dispense it.

Is naltrexone addictive?

No. Naltrexone is an opioid antagonist, not an opioid, and it does not cause euphoria, physical dependence, or addiction. However, it must not be taken while opioids are in your system, as it can trigger sudden withdrawal.

Can I take naltrexone with pain medication?

Naltrexone blocks opioid receptors, so opioid pain medicines will not work while you take it, and combining them can be dangerous. Tell every provider you see that you take naltrexone, and discuss non-opioid pain options with your prescriber.

How does ordering and shipping work?

After you place your order and provide your prescription (or complete a provider review where available), a licensed pharmacist verifies it before dispensing. Your medication then ships in discreet packaging from our licensed U.S. pharmacy.

What are common side effects of naltrexone?

The most common side effects include nausea, headache, dizziness, trouble sleeping or vivid dreams, and fatigue. Many effects are mild and improve over time, but contact your provider if symptoms persist or you notice signs of liver problems such as dark urine or yellowing skin.