Sertraline 100mg

Generic For: Zoloft

Sertraline 100mg (brand name Zoloft) is a selective serotonin reuptake inhibitor (SSRI) prescribed for major depressive disorder, obsessive-compulsive disorder, panic disorder, PTSD, and other conditions. After a licensed provider reviews your prescription, your sertraline order ships from a licensed U.S. pharmacy.

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  3. Our licensed U.S. pharmacists fill your prescription
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Buy Sertraline 100mg Online

An SSRI antidepressant for depression, anxiety-related disorders, and OCD

Sertraline 100mg Quick Facts

Drug classSelective serotonin reuptake inhibitor (SSRI)
TreatsDepression, OCD, panic disorder, PTSD
FormTablet
Typical dosingTake 1 tablet by mouth daily.
Prescription requiredYes — prescription only

What Is Sertraline 100mg?

Sertraline is a prescription antidepressant in the selective serotonin reuptake inhibitor (SSRI) class, sold under the brand name Zoloft. It works by increasing the availability of serotonin, a chemical messenger in the brain that influences mood, anxiety, and behavior. Sertraline is FDA-approved to treat major depressive disorder, obsessive-compulsive disorder, panic disorder, post-traumatic stress disorder, social anxiety disorder, and premenstrual dysphoric disorder. It is taken once daily as a tablet, and it may take several weeks to feel its full effect.

What Does Sertraline 100mg Treat?

Major depressive disorder (MDD)
Obsessive-compulsive disorder (OCD)
Panic disorder
Post-traumatic stress disorder (PTSD)
Social anxiety disorder
Premenstrual dysphoric disorder (PMDD)

Sertraline 100mg Dosage

MDD/OCD: 50 mg by mouth once daily; may titrate weekly to max 200 mg daily.
Panic disorder, PTSD, social anxiety disorder: 25 mg once daily for 1 week, then 50 mg once daily; max 200 mg daily.
PMDD: 50 mg once daily, continuously or during the luteal phase, per prescriber.

Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.

Sertraline 100mg Side Effects

Common side effects

  • Nausea
  • Diarrhea or loose stools
  • Insomnia or drowsiness
  • Dry mouth
  • Dizziness
  • Increased sweating
  • Decreased appetite
  • Sexual side effects (decreased libido, delayed ejaculation)

Serious side effects

Stop taking this medication and seek medical attention right away if you experience:

  • Suicidal thoughts or behavior, especially in those under 25
  • Serotonin syndrome (agitation, rapid heartbeat, fever, muscle rigidity)
  • Unusual bleeding or bruising
  • Seizures
  • Low sodium levels (hyponatremia): headache, confusion, weakness
  • Manic episodes (racing thoughts, unusual energy, impulsive behavior)

Warnings & Interactions

Boxed warning: increased risk of suicidal thoughts and behaviors in children, adolescents, and young adults
Do not use with MAOIs or within 14 days of stopping an MAOI
Do not use with pimozide
Oral solution (not tablets) is contraindicated with disulfiram
Increased bleeding risk with NSAIDs, aspirin, or blood thinners
Risk of serotonin syndrome with other serotonergic drugs (triptans, tramadol, St. John's Wort)
Do not stop abruptly; taper under provider guidance to avoid discontinuation symptoms

Tell your prescriber about all medications, supplements, and health conditions before starting sertraline 100mg.

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Frequently Asked Questions

What is sertraline used for?

Sertraline is FDA-approved to treat major depressive disorder, obsessive-compulsive disorder, panic disorder, PTSD, social anxiety disorder, and premenstrual dysphoric disorder. Your provider will determine whether it is appropriate for your condition.

Is sertraline the same as Zoloft?

Yes. Sertraline is the generic name for Zoloft. Generic sertraline contains the same active ingredient and is held to the same FDA standards for quality and effectiveness.

Do I need a prescription for sertraline?

Yes. Sertraline is a prescription-only medication in the United States. A licensed healthcare provider must evaluate you and issue a valid prescription before we can dispense it.

How long does sertraline take to work?

Some people notice improvement in sleep, energy, or appetite within 1 to 2 weeks, but the full effect on mood and anxiety often takes 4 to 6 weeks or longer. Continue taking it as prescribed and follow up with your provider.

How does ordering and shipping work?

After you submit your prescription, our licensed pharmacists verify it and a provider review is completed if required. Your medication then ships discreetly from our licensed U.S. pharmacy, and our team is available if you have questions.

Can I stop taking sertraline suddenly?

No. Stopping sertraline abruptly can cause discontinuation symptoms such as dizziness, irritability, and sleep problems. Talk with your provider about a gradual tapering plan.

What should I avoid while taking sertraline?

Avoid MAOIs, pimozide, and limit alcohol. Tell your provider about all medications and supplements you take, especially NSAIDs, blood thinners, triptans, tramadol, and St. John's Wort, due to bleeding and serotonin syndrome risks.