Sertraline 25mg
Generic For: Zoloft
Sertraline 25mg is the generic form of Zoloft, a selective serotonin reuptake inhibitor (SSRI) used to treat major depressive disorder, obsessive-compulsive disorder, panic disorder, and other anxiety-related conditions. It is often compared with medications like fluoxetine and duloxetine, but the right choice depends on your health history and a provider's judgment. After a licensed provider reviews your prescription, your order ships from a licensed U.S. pharmacy.
Compare all Sertraline options →
Select Quantity *
30-day supply · $0.83/tablet
How It Works
- Select your medication
- Licensed providers review & prescribe
- Our licensed U.S. pharmacists fill your prescription
- Delivered to you as soon as the next day
Price: $25.00
HSA/FSA Eligible*Doctor visit fee & delivery cost not included in price. Refills at provider discretion.
Buy Sertraline 25mg (Zoloft) Online
An SSRI antidepressant for depression, anxiety-related disorders, and OCD
Sertraline 25mg Quick Facts
| Drug class | SSRI antidepressant |
|---|---|
| Treats | Depression, OCD, panic disorder, PTSD |
| Form | Tablet |
| Typical dosing | Take 1 tablet by mouth daily. |
| Prescription required | Yes — prescription only |
What Is Sertraline 25mg?
Sertraline is a selective serotonin reuptake inhibitor (SSRI) sold under the brand name Zoloft. It works by increasing the availability of serotonin, a chemical messenger in the brain that influences mood, anxiety, and behavior. Patients researching sertraline vs fluoxetine or duloxetine vs sertraline should know these medications belong to related but distinct classes and are chosen based on individual symptoms, side-effect profiles, and medical history. The 25mg tablet is a common starting dose that a provider may adjust over time.
What Does Sertraline 25mg Treat?
Major depressive disorder (MDD)
Obsessive-compulsive disorder (OCD)
Panic disorder
Post-traumatic stress disorder (PTSD)
Social anxiety disorder
Premenstrual dysphoric disorder (PMDD)
Sertraline 25mg Dosage
MDD/OCD: 50 mg by mouth once daily; may start at 25 mg once daily.
Panic disorder, PTSD, social anxiety disorder: 25 mg by mouth once daily for 1 week, then 50 mg once daily.
Maximum: 200 mg once daily; adjust at intervals of at least 1 week per prescriber.
Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.
Sertraline 25mg Side Effects
Common side effects
- Nausea
- Diarrhea or loose stools
- Insomnia or drowsiness
- Dry mouth
- Dizziness
- Increased sweating
- Decreased appetite
- Sexual side effects
Serious side effects
Stop taking this medication and seek medical attention right away if you experience:
- Suicidal thoughts or behavior, especially in young adults
- Serotonin syndrome (agitation, rapid heartbeat, fever, muscle rigidity)
- Abnormal bleeding or easy bruising
- Manic episodes (racing thoughts, unusual energy)
- Seizures
- Low sodium levels (headache, confusion, weakness)
Warnings & Interactions
Boxed warning: increased risk of suicidal thoughts in children, adolescents, and young adults
Do not use with or within 14 days of MAOIs
Do not take with pimozide
Avoid combining with other serotonergic drugs (triptans, tramadol, St. John's Wort) without provider guidance
Increased bleeding risk with NSAIDs, aspirin, or blood thinners
Do not stop abruptly; taper under provider supervision
Oral solution is contraindicated with disulfiram
Tell your prescriber about all medications, supplements, and health conditions before starting sertraline 25mg.
Sources & References
Talk to U.S.-Based Support
Our licensed pharmacy team in Boca Raton, Florida — real people, no overseas call centers.


