Simvastatin 20mg
Generic For: Zocor
Simvastatin 20mg (brand name Zocor) is a statin medication used to lower LDL ("bad") cholesterol and triglycerides and to reduce the risk of heart attack and stroke in people at elevated cardiovascular risk. Many patients compare simvastatin vs atorvastatin when choosing a statin; both work similarly, and your prescriber can help determine which is right for you. After a licensed provider reviews your prescription, your order ships from a licensed U.S. pharmacy.
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90-day supply · $0.28/tablet
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Buy Simvastatin 20mg Online
An HMG-CoA reductase inhibitor (statin) for high cholesterol, high triglycerides, and reducing cardiovascular risk
Simvastatin 20mg Quick Facts
| Drug class | HMG-CoA reductase inhibitor (statin) |
|---|---|
| Treats | High cholesterol, high triglycerides, cardiovascular risk reduction |
| Form | Tablet |
| Typical dosing | Take 1 tablet by mouth daily at bedtime. |
| Prescription required | Yes — prescription only |
What Is Simvastatin 20mg?
Simvastatin is a prescription statin that works by blocking an enzyme your liver uses to make cholesterol. This lowers LDL cholesterol and triglycerides while modestly raising HDL ("good") cholesterol. It is prescribed alongside diet and lifestyle changes to reduce the risk of heart attack, stroke, and other cardiovascular events. In comparisons of atorvastatin vs simvastatin, both belong to the same drug class, though they differ in potency and drug interactions, so treatment choice is individualized by your provider.
What Does Simvastatin 20mg Treat?
High LDL cholesterol (primary hyperlipidemia)
Mixed dyslipidemia (high cholesterol and triglycerides)
Reduction of cardiovascular risk in patients with coronary heart disease or diabetes
Hypertriglyceridemia
Primary dysbetalipoproteinemia
Homozygous familial hypercholesterolemia (adjunct)
Simvastatin 20mg Dosage
Usual starting dose: 10–20 mg by mouth once daily in the evening.
Maintenance range: 5–40 mg once daily in the evening.
80 mg dose restricted to patients tolerating it for 12+ months without muscle toxicity.
Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.
Simvastatin 20mg Side Effects
Common side effects
- Headache
- Muscle aches
- Nausea
- Constipation
- Abdominal pain
- Upper respiratory infection symptoms
- Elevated liver enzymes (usually mild)
Serious side effects
Stop taking this medication and seek medical attention right away if you experience:
- Unexplained muscle pain, tenderness, or weakness (possible myopathy/rhabdomyolysis)
- Dark or tea-colored urine
- Signs of liver problems (yellowing skin/eyes, severe fatigue, dark urine)
- Severe allergic reaction (rash, swelling, difficulty breathing)
- New or worsening symptoms of high blood sugar
- Immune-mediated necrotizing myopathy (rare)
Warnings & Interactions
Do not use during pregnancy or while breastfeeding
Contraindicated with strong CYP3A4 inhibitors (e.g., itraconazole, clarithromycin, HIV protease inhibitors)
Avoid or limit grapefruit juice
Do not exceed dosing limits when combined with amiodarone, verapamil, diltiazem, or amlodipine
Contraindicated in active liver disease or unexplained persistent liver enzyme elevations
Increased risk of muscle injury with gemfibrozil, cyclosporine, or danazol — avoid combination
Report unexplained muscle pain or weakness to your provider promptly
Tell your prescriber about all medications, supplements, and health conditions before starting simvastatin 20mg.
Sources & References
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