Terconazole 0.4% Vaginal Cream
Terconazole 0.4% vaginal cream is a prescription azole antifungal used to treat vaginal yeast infections (vulvovaginal candidiasis). Applied intravaginally once daily at bedtime for 7 days, it works by stopping the growth of the Candida fungus. After a licensed provider reviews your prescription, your medication ships from a licensed U.S. pharmacy.
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7-day supply · $1.33/gram
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Terconazole vaginal cream — an azole antifungal for vaginal yeast infections (vulvovaginal candidiasis)
Terconazole 0.4% Vaginal Cream Quick Facts
| Drug class | Azole antifungal |
|---|---|
| Treats | Vaginal yeast infections, vulvovaginal candidiasis |
| Form | Cream |
| Typical dosing | Insert one applicatorful into the vagina at bedtime for 7 nights. Use only in the vaginal area. Avoid contact with the eyes and mouth. Complete all 7 nights, even if symptoms improve sooner. |
| Prescription required | Yes — prescription only |
What Is Terconazole 0.4% Vaginal Cream?
Terconazole vaginal cream is a prescription antifungal medication in the azole class. It is used to treat vaginal yeast infections caused by Candida, a common fungal infection that can cause itching, burning, and discharge. The 0.4% cream is inserted into the vagina with an applicator once daily at bedtime, typically for 7 consecutive days. Terconazole works by disrupting the fungal cell membrane, which stops the yeast from growing.
What Does Terconazole 0.4% Vaginal Cream Treat?
Vulvovaginal candidiasis (vaginal yeast infection)
Vaginal itching caused by Candida infection
Vaginal burning and irritation from yeast infection
Abnormal vaginal discharge due to candidiasis
Terconazole 0.4% Vaginal Cream Dosage
Insert 1 applicatorful (5 g) intravaginally once daily at bedtime for 7 consecutive days.
Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.
Terconazole 0.4% Vaginal Cream Side Effects
Common side effects
- Headache
- Vaginal or genital itching
- Vaginal burning or irritation
- Body aches or pain
- Menstrual cramps or abdominal pain
- Fever or chills (flu-like symptoms)
Serious side effects
Stop taking this medication and seek medical attention right away if you experience:
- Signs of allergic reaction (rash, hives, swelling of face or throat)
- Anaphylaxis (difficulty breathing, severe swelling)
- Toxic epidermal necrolysis (severe blistering or peeling skin)
- Severe or worsening vaginal irritation
- Flu-like syndrome with fever and low blood pressure
Warnings & Interactions
Do not use if allergic to terconazole or any ingredient in the cream
Discontinue and contact your provider if fever, chills, or flu-like symptoms develop
Discontinue if sensitization or severe irritation occurs
Confirm diagnosis with your provider; recurrent infections may need further evaluation
Cream base may weaken latex condoms and diaphragms; avoid relying on them during treatment
Use during pregnancy only if directed by your healthcare provider
For vaginal use only; avoid contact with eyes and mouth
Tell your prescriber about all medications, supplements, and health conditions before starting terconazole 0.4% vaginal cream.
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