Do I need a prescription for Trazodone 150mg?

Yes. Trazodone is a prescription-only medication in the United States. A licensed provider must review your health information and issue or verify a valid prescription before the pharmacy can dispense it.

Can I take cyclobenzaprine and trazodone together?

Combining cyclobenzaprine and trazodone can increase drowsiness, dizziness, and the risk of serotonin syndrome. Some prescribers may still use both with monitoring, but never combine them on your own. Tell your provider and pharmacist about all medications you take.

Can I take trazodone and fluoxetine together?

Trazodone and fluoxetine both raise serotonin levels, which increases the risk of serotonin syndrome, and fluoxetine can raise trazodone blood levels. Prescribers sometimes combine them at adjusted doses with close monitoring. Only use this combination under direct medical supervision.

How does ordering and shipping work?

After you upload or transfer a valid prescription, a licensed provider or pharmacist reviews your order. Once approved, your medication ships from a licensed U.S. pharmacy in discreet packaging, typically within a few business days.

How long does trazodone take to work for depression?

Some people notice improved sleep within the first week, but the full antidepressant effect may take 2 to 4 weeks or longer. Keep taking it as prescribed and follow up with your provider about your progress.

Can I drink alcohol while taking trazodone?

Alcohol should be avoided. It can intensify trazodone's sedative effects, increasing drowsiness, dizziness, and the risk of falls or impaired driving. Ask your prescriber about your individual risk.

Should I take trazodone with food?

Yes. Per FDA labeling, trazodone should be taken shortly after a meal or a light snack, which improves absorption consistency and may reduce dizziness. Take it at the same time(s) each day as directed.

Trazodone 150mg

Name: Trazodone 150mg
Brand: All Family Pharmacy
SKU: trazodone-150mg
Availability: InStock

Generic For: Desyrel

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Trazodone 150mg (brand name Desyrel) is a prescription antidepressant used to treat major depressive disorder. Because it can cause drowsiness, prescribers sometimes select it for patients whose depression includes insomnia. Your order ships from a licensed U.S. pharmacy after a licensed provider reviews your prescription.

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Buy Trazodone 150mg Online

A serotonin modulator antidepressant for major depressive disorder, including depression with anxiety or trouble sleeping

Medically reviewed by David Paul Mackarey, RPh, Pharmacist-in-Charge

Trazodone 150mg Quick Facts

Drug class	Serotonin modulator antidepressant
Treats	Major depressive disorder, depression with anxiety, depression with insomnia
Form	Tablet
Typical dosing	Take 1 tablet by mouth daily.
Prescription required	Yes — prescription only

What Is Trazodone 150mg?

Trazodone is a prescription antidepressant classified as a serotonin receptor antagonist and reuptake inhibitor (SARI). It works by adjusting serotonin activity in the brain, which can help improve mood over several weeks of consistent use. It is FDA-approved to treat major depressive disorder in adults. Because trazodone commonly causes drowsiness, it is often taken near bedtime, and questions about combining it with other medicines — such as trazodone and fluoxetine or cyclobenzaprine and trazodone — should always be reviewed with a pharmacist or prescriber.

What Does Trazodone 150mg Treat?

Major depressive disorder (FDA-approved)
Depression with anxiety symptoms
Depression accompanied by insomnia
Maintenance treatment to help prevent depression relapse
Insomnia (off-label, at prescriber discretion)

Trazodone 150mg Dosage

Start: 150 mg by mouth daily in divided doses, taken shortly after a meal or snack
Titrate: may increase by 50 mg/day every 3–4 days as directed
Max: 400 mg/day (outpatient); 600 mg/day (inpatient), per prescriber

Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.

Trazodone 150mg Side Effects

Common side effects

Drowsiness or sedation
Dizziness or lightheadedness
Dry mouth
Headache
Nausea or vomiting
Blurred vision
Fatigue
Constipation

Serious side effects

Stop taking this medication and seek medical attention right away if you experience:

Suicidal thoughts or behavior (boxed warning, especially in young adults)
Serotonin syndrome (agitation, fever, rapid heartbeat, muscle rigidity)
Priapism (painful erection lasting more than 4 hours)
Irregular heartbeat or QT prolongation
Severe drop in blood pressure or fainting
Unusual bleeding or bruising

Warnings & Interactions

Boxed warning: increased risk of suicidal thoughts in children, adolescents, and young adults
Do not use with or within 14 days of MAOI antidepressants
Risk of serotonin syndrome when combined with other serotonergic drugs (e.g., SSRIs such as fluoxetine)
Additive sedation with alcohol, muscle relaxants (e.g., cyclobenzaprine), opioids, and other CNS depressants
May cause orthostatic hypotension; rise slowly from sitting or lying down
Avoid driving or operating machinery until you know how trazodone affects you
Do not stop abruptly; taper under medical supervision to avoid discontinuation symptoms

Tell your prescriber about all medications, supplements, and health conditions before starting trazodone 150mg.