Allopurinol 100mg

Generic For: Zyloprim

Allopurinol (brand name Zyloprim) is a prescription xanthine oxidase inhibitor that lowers uric acid levels in the blood. It is used to manage gout, hyperuricemia caused by cancer treatment, and recurrent calcium oxalate kidney stones. After a licensed provider reviews your prescription, your order ships from a licensed U.S. pharmacy.

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Buy Allopurinol 100mg Tablets Online

A xanthine oxidase inhibitor for gout, high uric acid levels, and certain kidney stones

Allopurinol 100mg Quick Facts

Drug classXanthine oxidase inhibitor
TreatsGout, high uric acid, recurrent kidney stones
FormTablet
Typical dosingTake 1 tablet by mouth daily as needed for gout.
Prescription requiredYes — prescription only

What Is Allopurinol 100mg?

Allopurinol is a prescription medication that reduces the amount of uric acid your body produces. It works by blocking xanthine oxidase, the enzyme responsible for making uric acid. Doctors prescribe allopurinol to manage gout, to prevent high uric acid levels during cancer treatment, and to help prevent certain recurrent kidney stones. It is a long-term maintenance medication and does not relieve an acute gout attack once one has started.

What Does Allopurinol 100mg Treat?

Management of gout (gouty arthritis and tophi)
Hyperuricemia associated with cancer chemotherapy (leukemia, lymphoma, solid tumors)
Prevention of recurrent calcium oxalate kidney stones in patients with hyperuricosuria
Long-term reduction of elevated blood uric acid levels

Allopurinol 100mg Dosage

Gout: Start 100 mg by mouth once daily; increase by 100 mg weekly as needed. Usual maintenance 200–300 mg/day (mild) or 400–600 mg/day (severe); max 800 mg/day.
Recurrent kidney stones: 200–300 mg by mouth daily in single or divided doses.
Doses above 300 mg/day should be given in divided doses; reduce dose in renal impairment.

Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.

Allopurinol 100mg Side Effects

Common side effects

  • Skin rash
  • Nausea
  • Diarrhea
  • Drowsiness
  • Upset stomach
  • Increased gout flares when starting treatment
  • Elevated liver enzymes

Serious side effects

Stop taking this medication and seek medical attention right away if you experience:

  • Severe skin reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis)
  • Allopurinol hypersensitivity syndrome (fever, rash, organ involvement)
  • Liver injury (jaundice, dark urine, abdominal pain)
  • Unusual bleeding, bruising, or signs of low blood counts
  • Severe allergic reaction (swelling of face, lips, or throat; difficulty breathing)

Warnings & Interactions

Stop taking allopurinol at the first sign of a skin rash and contact your provider immediately
Do not use if you have had a prior severe reaction to allopurinol
Dose adjustment required in kidney impairment
Major interaction: azathioprine and mercaptopurine (doses must be substantially reduced)
Increased rash risk with ampicillin or amoxicillin
May increase bleeding risk with warfarin; monitoring recommended
Drink plenty of fluids to maintain adequate urine output

Tell your prescriber about all medications, supplements, and health conditions before starting allopurinol 100mg.

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Frequently Asked Questions

What is allopurinol used for?

Allopurinol is used to lower uric acid levels in the blood. It is FDA-approved to manage gout, hyperuricemia caused by cancer chemotherapy, and to help prevent recurrent calcium oxalate kidney stones in certain patients.

Do I need a prescription for allopurinol?

Yes, allopurinol is a prescription-only medication in the United States. A licensed healthcare provider must evaluate you and issue a valid prescription before we can dispense it.

How does ordering and shipping work?

After you place your order, a licensed provider or pharmacist reviews your prescription information. Once approved, your medication is dispensed and shipped from a licensed U.S. pharmacy directly to your address.

How long does allopurinol take to work?

Allopurinol begins lowering uric acid within a few days, but it can take several weeks to months to reach target uric acid levels and reduce gout flares. Gout attacks may temporarily increase when you first start treatment, which is expected.

Can allopurinol treat a gout attack that has already started?

No, allopurinol does not relieve an acute gout flare and is not a pain reliever. It is a long-term medication that lowers uric acid over time; your provider may prescribe other medications for acute attacks.

What should I avoid while taking allopurinol?

Tell your provider about all medications you take, especially azathioprine, mercaptopurine, and warfarin, which have major interactions. Stop the medication and seek care immediately if you develop a skin rash, and stay well hydrated while taking allopurinol.

Is Zyloprim the same as allopurinol?

Yes, Zyloprim is a brand name for allopurinol. Generic allopurinol contains the same active ingredient and meets the same FDA standards for quality and effectiveness.