Allopurinol 300mg
Generic For: Zyloprim
Allopurinol 300mg (Zyloprim) is a prescription tablet that lowers uric acid levels in the body. It is used to manage gout, hyperuricemia associated with cancer treatment, and recurrent calcium oxalate kidney stones. After a licensed provider reviews your prescription, your order ships from a licensed U.S. pharmacy.
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100-day supply · $0.35/tablet
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Buy Allopurinol 300mg Online
A xanthine oxidase inhibitor for gout, high uric acid levels, and certain kidney stones
Allopurinol 300mg Quick Facts
| Drug class | Xanthine oxidase inhibitor |
|---|---|
| Treats | Gout, high uric acid, recurrent kidney stones |
| Form | Tablet |
| Typical dosing | Take 1 tablet by mouth daily as needed for gout. |
| Prescription required | Yes — prescription only |
What Is Allopurinol 300mg?
Allopurinol is a xanthine oxidase inhibitor that reduces the amount of uric acid your body produces. High uric acid can cause gout flares, joint damage, and certain types of kidney stones. Allopurinol is taken daily as a long-term therapy to keep uric acid levels down; it does not treat an acute gout attack that is already underway. It is available as a generic tablet and under the brand name Zyloprim.
What Does Allopurinol 300mg Treat?
Gout (long-term management of hyperuricemia)
Hyperuricemia associated with cancer chemotherapy (leukemia, lymphoma, other malignancies)
Recurrent calcium oxalate kidney stones
Prevention of uric acid nephropathy during cancer treatment
Allopurinol 300mg Dosage
Gout (mild): 200–300 mg by mouth once daily
Gout (moderately severe): 400–600 mg by mouth daily in divided doses
Maximum: 800 mg daily; take after meals; adjust for renal impairment
Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.
Allopurinol 300mg Side Effects
Common side effects
- Skin rash
- Nausea
- Diarrhea
- Drowsiness
- Headache
- Increased gout flares when starting therapy
- Elevated liver enzymes
Serious side effects
Stop taking this medication and seek medical attention right away if you experience:
- Severe skin reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis)
- Allopurinol hypersensitivity syndrome (fever, rash, organ involvement)
- Liver injury (jaundice, dark urine, abdominal pain)
- Blood disorders (unusual bleeding, bruising, infections)
- Severe allergic reaction (swelling of face, lips, or throat; difficulty breathing)
Warnings & Interactions
Stop immediately at the first sign of skin rash and contact your provider
Higher risk of severe skin reactions in patients with the HLA-B*58:01 allele
Dose adjustment required in kidney impairment
Increases levels of azathioprine and mercaptopurine — doses must be reduced
May increase bleeding risk with warfarin; monitor INR
Gout flares may occur when starting; do not stop without consulting your provider
Use caution with alcohol and thiazide diuretics
Tell your prescriber about all medications, supplements, and health conditions before starting allopurinol 300mg.
Sources & References
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