Colchicine 0.6mg

Generic For: Colcrys

Colchicine 0.6mg (brand name Colcrys) is a prescription anti-inflammatory tablet used to treat and prevent gout flares and to manage familial Mediterranean fever (FMF). It works by reducing the inflammation that causes sudden joint pain and swelling. After a licensed provider reviews your prescription, your order ships from a licensed U.S. pharmacy.

Select Quantity *

33-day supply · $0.40/tablet

How It Works

  1. Select your medication
  2. Licensed providers review & prescribe
  3. Our licensed U.S. pharmacists fill your prescription
  4. Delivered to you as soon as the next day

Price: $40.00

HSA/FSA Eligible
Get Started

*Doctor visit fee & delivery cost not included in price. Refills at provider discretion.

Pharmacist Support Fast Shipping Licensed U.S. Pharmacy

Buy Colchicine 0.6mg (Colcrys) Online

An anti-gout anti-inflammatory medication for gout flares, gout prevention, and familial Mediterranean fever

Colchicine 0.6mg Quick Facts

Drug classAnti-gout agent (alkaloid)
TreatsGout flares, gout flare prevention, familial Mediterranean fever
FormTablet
Typical dosingTake 2 tablets by mouth at the first sign of a gout flare, then 1 tablet 1 hour later. Maximum 3 tablets (1.8 mg) in 24 hours.
Prescription requiredYes — prescription only

What Is Colchicine 0.6mg?

Colchicine is a plant-derived medication that has been used for decades to treat gout, one of the most common forms of inflammatory arthritis. It reduces the buildup of inflammatory cells that respond to uric acid crystals in joints, easing pain and swelling during a flare. Colchicine is also FDA-approved to prevent gout flares and to treat familial Mediterranean fever, an inherited inflammatory condition. It is available as a 0.6mg tablet under the brand name Colcrys and requires a prescription in the United States.

What Does Colchicine 0.6mg Treat?

Treatment of acute gout flares
Prevention of gout flares in adults
Gout flare prophylaxis when starting urate-lowering therapy
Familial Mediterranean fever (FMF) in adults
Familial Mediterranean fever (FMF) in children 4 years and older

Colchicine 0.6mg Dosage

Gout flare: 1.2 mg (2 tablets) by mouth at first sign of flare, then 0.6 mg (1 tablet) 1 hour later; max 1.8 mg over 1 hour
Gout prophylaxis: 0.6 mg by mouth once or twice daily; max 1.2 mg/day
FMF (adults): 1.2–2.4 mg by mouth daily in 1 or 2 divided doses

Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.

Colchicine 0.6mg Side Effects

Common side effects

  • Diarrhea
  • Nausea
  • Vomiting
  • Abdominal pain or cramping
  • Fatigue
  • Headache
  • Sore throat (in FMF patients)

Serious side effects

Stop taking this medication and seek medical attention right away if you experience:

  • Muscle pain or weakness (myopathy/rhabdomyolysis)
  • Unusual bleeding or bruising, signs of low blood counts
  • Numbness or tingling in fingers or toes
  • Signs of severe infection (fever, chills)
  • Severe or persistent diarrhea or vomiting (possible toxicity)
  • Pale or gray lips, tongue, or palms

Warnings & Interactions

Do not take with strong CYP3A4 inhibitors (e.g., clarithromycin, ketoconazole) or P-gp inhibitors if you have kidney or liver impairment — fatal toxicity has occurred
Use caution with statins and fibrates due to increased risk of muscle injury
Dose adjustment needed for kidney or liver disease
Avoid grapefruit and grapefruit juice
Blood disorders (low blood cell counts) have been reported
Colchicine overdose can be fatal; keep out of reach of children
Tell your provider about all medications before starting colchicine

Tell your prescriber about all medications, supplements, and health conditions before starting colchicine 0.6mg.

Talk to U.S.-Based Support

Our licensed pharmacy team in Boca Raton, Florida — real people, no overseas call centers.

Frequently Asked Questions

What is colchicine used for?

Colchicine is FDA-approved to treat and prevent gout flares in adults and to treat familial Mediterranean fever (FMF) in adults and children 4 and older. It reduces the inflammation that causes joint pain and swelling. It is not a general pain reliever and should only be used as prescribed.

How quickly does colchicine work for a gout flare?

Colchicine works best when taken at the first sign of a gout flare, and many people notice improvement within 24 hours. The standard regimen is 1.2 mg at the first sign of a flare followed by 0.6 mg one hour later. Do not exceed the prescribed dose, as higher doses increase side effects without added benefit.

Do I need a prescription for colchicine?

Yes. Colchicine is a prescription-only medication in the United States. A licensed healthcare provider must review your health information and prescribe it before a pharmacy can dispense it.

How does ordering and shipping work?

After you place your order and provide a valid prescription (or complete a provider review where available), our pharmacy team verifies it before dispensing. Your medication then ships from a licensed U.S. pharmacy in discreet packaging.

What are the most common side effects of colchicine?

The most common side effects are gastrointestinal, including diarrhea, nausea, vomiting, and abdominal pain. Severe or persistent diarrhea or vomiting can be an early sign of toxicity, so contact your provider if these occur.

Can I take colchicine with my other medications?

Colchicine has serious interactions with certain antibiotics, antifungals, and heart medications that block CYP3A4 or P-glycoprotein, and caution is needed with statins. Fatal interactions have occurred, especially in people with kidney or liver problems. Always share your full medication list with your provider and pharmacist.

Should I avoid grapefruit while taking colchicine?

Yes. Grapefruit and grapefruit juice can raise colchicine levels in your blood and increase the risk of serious toxicity. Avoid them while taking this medication.