Famotidine 40mg

Generic For: Pepcid

Famotidine 40mg (brand name Pepcid) is a prescription-strength histamine-2 (H2) blocker that reduces the amount of acid your stomach makes. It is used to treat GERD, stomach and duodenal ulcers, and other conditions caused by excess stomach acid. After a licensed provider reviews your order, your medication ships from a licensed U.S. pharmacy.

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50-day supply · $0.25/tablet

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  1. Select your medication
  2. Licensed providers review & prescribe
  3. Our licensed U.S. pharmacists fill your prescription
  4. Delivered to you as soon as the next day

Price: $25.00

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*Doctor visit fee & delivery cost not included in price. Refills at provider discretion.

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Buy Famotidine 40mg (Pepcid) Online

Prescription-strength H2 blocker for GERD, stomach ulcers, and acid reflux

Famotidine 40mg Quick Facts

Drug classHistamine-2 (H2) blocker
TreatsGERD, stomach ulcers, duodenal ulcers, erosive esophagitis
FormTablet
Typical dosingTake 1 tablet by mouth daily as needed for heartburn.
Prescription requiredYes — prescription only

What Is Famotidine 40mg?

Famotidine is a histamine-2 (H2) receptor blocker that decreases acid production in the stomach. While lower strengths (10mg and 20mg) are available over the counter for heartburn, the 40mg tablet is prescription strength and requires a prescription in the U.S. Prescription famotidine is used to treat gastroesophageal reflux disease (GERD), ulcers of the stomach and small intestine, and conditions where the stomach produces too much acid. It is the generic version of Pepcid and is taken by mouth, typically once or twice daily as directed by your provider.

What Does Famotidine 40mg Treat?

Gastroesophageal reflux disease (GERD)
Duodenal ulcers (active treatment and maintenance)
Active gastric (stomach) ulcers
Erosive esophagitis due to GERD
Pathological hypersecretory conditions (e.g., Zollinger-Ellison syndrome)
Heartburn and acid indigestion (lower OTC strengths)

Famotidine 40mg Dosage

Duodenal ulcer: 40 mg by mouth once daily at bedtime for 4–8 weeks
GERD: 20 mg by mouth twice daily for up to 6 weeks
Erosive esophagitis: 20–40 mg by mouth twice daily for up to 12 weeks

Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.

Famotidine 40mg Side Effects

Common side effects

  • Headache
  • Dizziness
  • Constipation
  • Diarrhea
  • Nausea
  • Fatigue
  • Dry mouth

Serious side effects

Stop taking this medication and seek medical attention right away if you experience:

  • Confusion, agitation, or hallucinations (especially in older adults or kidney impairment)
  • Irregular or rapid heartbeat
  • Severe allergic reaction (rash, hives, swelling of face or throat, trouble breathing)
  • Unusual bruising or bleeding
  • Signs of liver problems (yellowing skin or eyes, dark urine)
  • Seizures (rare, mainly with kidney impairment)

Warnings & Interactions

Do not use if allergic to famotidine or other H2 blockers (e.g., cimetidine, ranitidine)
Dose adjustment needed for moderate to severe kidney impairment
Symptom relief does not rule out stomach cancer; persistent symptoms need evaluation
CNS side effects (confusion, delirium) reported in elderly and renally impaired patients
May reduce absorption of drugs that need stomach acid (e.g., certain antifungals, some HIV medications)
Tell your provider if you are pregnant, breastfeeding, or have kidney or liver disease

Tell your prescriber about all medications, supplements, and health conditions before starting famotidine 40mg.

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Frequently Asked Questions

Is famotidine over the counter?

Lower strengths of famotidine (10mg and 20mg, sold as Pepcid AC) are available over the counter for occasional heartburn. The 40mg tablet is prescription strength and requires a prescription from a licensed provider.

Can you buy famotidine over the counter?

Yes, you can buy famotidine 10mg or 20mg over the counter for short-term heartburn relief. Famotidine 40mg is only available with a prescription because it is used to treat conditions like GERD and ulcers that need medical supervision.

Does famotidine require a prescription?

Famotidine 40mg requires a prescription in the U.S. When you order through our pharmacy, a licensed provider reviews your health information and, if appropriate, issues a prescription before the medication ships.

How much is famotidine without insurance?

Generic famotidine is typically inexpensive, and cash prices without insurance are often modest, though they vary by pharmacy and quantity. Your final price is shown at checkout before you complete your order.

What is prescription strength famotidine?

Prescription strength famotidine is the 40mg tablet, double the highest over-the-counter dose. It is prescribed for GERD, active stomach and duodenal ulcers, erosive esophagitis, and conditions involving excess stomach acid.

What is the over the counter equivalent to famotidine?

Famotidine itself is sold over the counter at 10mg and 20mg strengths under the brand Pepcid AC. There is no OTC equivalent to the 40mg prescription strength, which should only be used under a provider's direction.

How does ordering and shipping work?

Complete a short health questionnaire online, and a licensed provider reviews your order. If famotidine 40mg is appropriate for you, your prescription is filled and shipped from a licensed U.S. pharmacy to your door.