Omeprazole 20mg
Generic For: Prilosec
Omeprazole 20mg (brand name Prilosec) is a proton pump inhibitor that reduces the amount of acid your stomach produces. It is prescribed to treat GERD, erosive esophagitis, and stomach and duodenal ulcers. After a licensed provider reviews your information, your order ships from a licensed U.S. pharmacy.
Compare all Omeprazole options →
Select Quantity *
100-day supply · $0.20/capsule
How It Works
- Select your medication
- Licensed providers review & prescribe
- Our licensed U.S. pharmacists fill your prescription
- Delivered to you as soon as the next day
Price: $20.00
HSA/FSA Eligible*Doctor visit fee & delivery cost not included in price. Refills at provider discretion.
Buy Omeprazole 20mg Online (Prilosec)
A proton pump inhibitor (PPI) for GERD, acid reflux, and stomach ulcers
Omeprazole 20mg Quick Facts
| Drug class | Proton pump inhibitor (PPI) |
|---|---|
| Treats | GERD, erosive esophagitis, stomach ulcers, duodenal ulcers |
| Form | Capsule |
| Typical dosing | Take 1 capsule by mouth daily one hour before a meal as needed for acid reflux. |
| Prescription required | Yes — prescription only |
What Is Omeprazole 20mg?
Omeprazole is a prescription medication in a class called proton pump inhibitors (PPIs). It works by blocking the pumps in the stomach lining that produce acid, lowering acid levels so damaged tissue in the esophagus and stomach can heal. Omeprazole 20mg capsules are commonly prescribed for gastroesophageal reflux disease (GERD), erosive esophagitis, and ulcers. It is the generic version of the brand-name drug Prilosec.
What Does Omeprazole 20mg Treat?
Gastroesophageal reflux disease (GERD)
Erosive esophagitis (healing and maintenance)
Duodenal ulcers
Gastric (stomach) ulcers
Helicobacter pylori eradication (with antibiotics)
Pathological hypersecretory conditions (e.g., Zollinger-Ellison syndrome)
Omeprazole 20mg Dosage
GERD / erosive esophagitis: 20 mg by mouth once daily for 4–8 weeks.
Duodenal ulcer: 20 mg by mouth once daily for 4 weeks.
Gastric ulcer: 40 mg by mouth once daily for 4–8 weeks.
Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.
Omeprazole 20mg Side Effects
Common side effects
- Headache
- Abdominal pain
- Nausea
- Diarrhea
- Vomiting
- Gas (flatulence)
- Dizziness
Serious side effects
Stop taking this medication and seek medical attention right away if you experience:
- Severe diarrhea (possible C. difficile infection)
- Signs of low magnesium (muscle spasms, irregular heartbeat, seizures)
- Kidney problems (acute interstitial nephritis)
- Severe skin reactions (rash, blistering, peeling)
- New or worsening lupus symptoms (joint pain, rash on cheeks or arms)
Warnings & Interactions
Do not use if allergic to omeprazole or other PPIs.
Long-term use may increase risk of bone fractures of the hip, wrist, or spine.
Prolonged use may cause low magnesium or vitamin B12 deficiency.
May interact with clopidogrel and reduce its effectiveness.
Avoid use with rilpivirine-containing products.
Can affect levels of drugs like methotrexate, warfarin, and diazepam.
May mask symptoms of gastric cancer; tell your provider about alarm symptoms.
Tell your prescriber about all medications, supplements, and health conditions before starting omeprazole 20mg.
Talk to U.S.-Based Support
Our licensed pharmacy team in Boca Raton, Florida — real people, no overseas call centers.


