Rabeprazole 20mg

Generic For: Aciphex

Rabeprazole 20mg (brand name Aciphex) is a proton pump inhibitor that reduces stomach acid production. It is used to treat GERD, heal erosive esophagitis and duodenal ulcers, and manage conditions involving excess stomach acid. After a licensed provider reviews your information, your prescription ships from a licensed U.S. pharmacy.

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Buy Rabeprazole 20mg (Aciphex) Online

A proton pump inhibitor for GERD, erosive esophagitis, and duodenal ulcers

Rabeprazole 20mg Quick Facts

Drug classProton pump inhibitor (PPI)
TreatsGERD, erosive esophagitis, duodenal ulcers, H. pylori infection
FormTablet
Typical dosingTake 1 tablet by mouth daily in the morning as needed for acid reflux.
Prescription requiredYes — prescription only

What Is Rabeprazole 20mg?

Rabeprazole is a prescription proton pump inhibitor (PPI) sold under the brand name Aciphex. It works by blocking the acid-producing pumps in the stomach lining, lowering the amount of acid your stomach makes. Less acid allows damaged tissue in the esophagus and stomach to heal and helps relieve symptoms like heartburn. Rabeprazole is taken as a delayed-release tablet, usually once daily.

What Does Rabeprazole 20mg Treat?

Gastroesophageal reflux disease (GERD)
Healing of erosive or ulcerative GERD
Maintenance of healed erosive GERD
Symptomatic GERD (daytime and nighttime heartburn)
Healing of duodenal ulcers
Helicobacter pylori eradication (with antibiotics)
Zollinger-Ellison syndrome and other hypersecretory conditions

Rabeprazole 20mg Dosage

GERD / erosive esophagitis: 20 mg by mouth once daily for 4–8 weeks; maintenance 20 mg once daily
Duodenal ulcer: 20 mg by mouth once daily after the morning meal for up to 4 weeks
H. pylori: 20 mg by mouth twice daily for 7 days with amoxicillin and clarithromycin

Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.

Rabeprazole 20mg Side Effects

Common side effects

  • Headache
  • Diarrhea
  • Nausea
  • Abdominal pain
  • Constipation
  • Gas (flatulence)
  • Sore throat

Serious side effects

Stop taking this medication and seek medical attention right away if you experience:

  • Severe or persistent diarrhea (possible C. difficile infection)
  • Signs of low magnesium (muscle spasms, irregular heartbeat, seizures)
  • Severe allergic reactions (rash, swelling, trouble breathing)
  • Kidney problems (acute interstitial nephritis)
  • New or worsening lupus-like symptoms (joint pain, rash on cheeks or arms)

Warnings & Interactions

Do not use if allergic to rabeprazole or other proton pump inhibitors
Do not take with rilpivirine-containing HIV medicines
Long-term use may increase risk of bone fractures and vitamin B12 deficiency
May increase risk of C. difficile–associated diarrhea
Can interact with warfarin, methotrexate, clopidogrel, and drugs needing stomach acid for absorption
May mask symptoms of gastric cancer; tell your provider about alarm symptoms
Tell your provider if you are pregnant or breastfeeding

Tell your prescriber about all medications, supplements, and health conditions before starting rabeprazole 20mg.

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Frequently Asked Questions

What is rabeprazole used for?

Rabeprazole is a proton pump inhibitor used to treat GERD, heal erosive esophagitis and duodenal ulcers, and treat H. pylori infection alongside antibiotics. It is also used for conditions that cause excess stomach acid, such as Zollinger-Ellison syndrome.

Is rabeprazole the same as Aciphex?

Yes. Rabeprazole is the generic name and Aciphex is the brand name of the same medication. Both contain rabeprazole sodium and work the same way to reduce stomach acid.

Do I need a prescription for rabeprazole 20mg?

Yes, rabeprazole 20mg is a prescription-only medication in the U.S. A licensed healthcare provider must evaluate whether it is appropriate for you before it can be dispensed.

How do ordering and shipping work?

After you place your order, a licensed provider reviews your health information or your existing prescription. Once approved, your medication is dispensed by a licensed U.S. pharmacy and shipped directly to your address.

How long does rabeprazole take to work?

Many people notice symptom relief within a few days, though full healing of the esophagus or an ulcer typically takes 4–8 weeks. Take it exactly as prescribed even if symptoms improve early.

How should I take rabeprazole?

Swallow the delayed-release tablet whole once daily, or as your provider directs; do not crush, split, or chew it. For duodenal ulcers it is usually taken after the morning meal.

Is rabeprazole safe for long-term use?

Some conditions require longer treatment, but long-term PPI use has been associated with risks such as bone fractures, low magnesium, and vitamin B12 deficiency. Use the lowest effective dose for the shortest duration your provider recommends.