Liothyronine 25mcg

Generic For: Cytomel

Liothyronine (brand name Cytomel) is a synthetic form of T3, the active thyroid hormone, used to treat hypothyroidism and certain types of goiter. After a licensed provider reviews your prescription, your liothyronine 25mcg tablets ship directly from a licensed U.S. pharmacy.

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90-day supply · $0.61/tablet

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Buy Liothyronine 25mcg (Cytomel) Online

A thyroid hormone (T3) replacement for hypothyroidism, goiter, and myxedema

Liothyronine 25mcg Quick Facts

Drug classThyroid hormone (T3)
TreatsHypothyroidism, goiter, myxedema, thyroid suppression testing
FormTablet
Typical dosingTake 1 tablet by mouth daily.
Prescription requiredYes — prescription only

What Is Liothyronine 25mcg?

Liothyronine is a man-made version of triiodothyronine (T3), one of the hormones your thyroid gland naturally produces. When the thyroid does not make enough hormone, liothyronine replaces it to help regulate metabolism, energy, and body temperature. It is the active ingredient in the brand-name medication Cytomel and is taken as a once-daily tablet. Unlike levothyroxine (T4), liothyronine works more quickly because it is already in the active hormone form.

What Does Liothyronine 25mcg Treat?

Hypothyroidism (underactive thyroid)
Myxedema (severe hypothyroidism)
Simple (non-toxic) goiter
Hypothyroidism secondary to pituitary disease (secondary hypothyroidism)
T3 suppression testing for suspected mild hyperthyroidism
Hypothyroidism following thyroid surgery or radioiodine therapy

Liothyronine 25mcg Dosage

Hypothyroidism: Start 25 mcg by mouth once daily; may increase by 25 mcg every 1–2 weeks. Usual maintenance: 25–75 mcg once daily.
Simple goiter: Start 5 mcg once daily; titrate as directed. Usual maintenance: 75 mcg once daily.
Myxedema: Start 5 mcg once daily; titrate slowly per prescriber.

Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.

Liothyronine 25mcg Side Effects

Common side effects

  • Headache
  • Irritability or nervousness
  • Trouble sleeping
  • Sweating
  • Increased appetite
  • Weight changes
  • Diarrhea
  • Menstrual cycle changes

Serious side effects

Stop taking this medication and seek medical attention right away if you experience:

  • Chest pain or pressure
  • Fast, pounding, or irregular heartbeat
  • Shortness of breath
  • Signs of allergic reaction (rash, swelling, difficulty breathing)
  • Extreme nervousness, tremor, or confusion
  • Worsening symptoms in patients with heart disease

Warnings & Interactions

Boxed warning: not for weight loss; large doses may cause serious or life-threatening effects
Do not use with untreated adrenal insufficiency or uncorrected adrenal cortical insufficiency
Do not use with untreated thyrotoxicosis
Use caution in patients with heart disease, angina, or high blood pressure
May alter blood sugar control; diabetic patients may need dose adjustments
Can increase the effect of blood thinners such as warfarin
Tell your prescriber about all medications, including estrogen products and antacids

Tell your prescriber about all medications, supplements, and health conditions before starting liothyronine 25mcg.

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Frequently Asked Questions

What is liothyronine used for?

Liothyronine is a synthetic T3 thyroid hormone used to treat hypothyroidism, myxedema, and simple goiter. It is also used in T3 suppression testing to help diagnose mild hyperthyroidism.

Is liothyronine the same as Cytomel?

Yes. Cytomel is the brand name for liothyronine sodium. Both contain the same active ingredient and work the same way when taken as prescribed.

Do I need a prescription for liothyronine?

Yes. Liothyronine is a prescription-only medication in the United States. A licensed provider must review your health history and prescribe it before a pharmacy can dispense it.

How does ordering and shipping work?

After you place your order, a licensed provider reviews your prescription or health information. Once approved, your medication is filled and shipped from a licensed U.S. pharmacy directly to your door.

How is liothyronine different from levothyroxine?

Levothyroxine is T4, a hormone your body converts into active T3, while liothyronine is T3 itself and acts more quickly. Your prescriber will determine which option is appropriate based on your lab results and symptoms.

Can liothyronine be used for weight loss?

No. Liothyronine carries an FDA boxed warning stating it should not be used for weight loss. Large doses can cause serious or life-threatening side effects, especially when combined with diet medications.

How should I take liothyronine 25mcg?

Take it exactly as prescribed, typically once daily. Do not change your dose or stop taking it without talking to your prescriber, and keep regular lab appointments to monitor your thyroid levels.