Atovaquone 750mg/5mL
Generic For: Mepron
Atovaquone 750mg/5mL oral suspension (brand name Mepron) is an antiprotozoal medication used to prevent and treat Pneumocystis jirovecii pneumonia (PCP) in adults and adolescents who cannot take trimethoprim-sulfamethoxazole. After a licensed provider reviews your prescription, your order ships from a licensed U.S. pharmacy.
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21-day supply · $0.76/mL
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Buy Atovaquone 750mg/5mL Oral Suspension (Mepron) Online
An antiprotozoal medication for the prevention and treatment of Pneumocystis jirovecii pneumonia (PCP)
Atovaquone 750mg/5mL Quick Facts
| Drug class | Antiprotozoal agent |
|---|---|
| Treats | PCP treatment, PCP prevention |
| Form | Suspension |
| Typical dosing | Take 5 mL by mouth twice a day with a meal for 21 days. |
| Prescription required | Yes — prescription only |
What Is Atovaquone 750mg/5mL?
Atovaquone is an antiprotozoal medicine sold under the brand name Mepron as a 750mg/5mL oral suspension. It works by blocking energy production in the organism that causes Pneumocystis jirovecii pneumonia (PCP), a serious lung infection most common in people with weakened immune systems. It is FDA-approved for both preventing and treating mild-to-moderate PCP in patients who cannot tolerate trimethoprim-sulfamethoxazole. Atovaquone should be taken with food to improve absorption.
What Does Atovaquone 750mg/5mL Treat?
Treatment of mild-to-moderate Pneumocystis jirovecii pneumonia (PCP)
Prevention of Pneumocystis jirovecii pneumonia (PCP)
PCP treatment in patients intolerant to trimethoprim-sulfamethoxazole
PCP prophylaxis in immunocompromised patients (e.g., HIV)
Atovaquone 750mg/5mL Dosage
PCP treatment: 750 mg (5 mL) by mouth twice daily with food for 21 days.
PCP prevention: 1500 mg (10 mL) by mouth once daily with food.
Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.
Atovaquone 750mg/5mL Side Effects
Common side effects
- Rash
- Nausea
- Diarrhea
- Headache
- Vomiting
- Fever
- Insomnia
- Cough
Serious side effects
Stop taking this medication and seek medical attention right away if you experience:
- Severe skin reactions (e.g., erythema multiforme)
- Signs of liver problems (jaundice, dark urine, severe fatigue)
- Severe or persistent vomiting or diarrhea preventing absorption
- Allergic reaction (swelling, difficulty breathing, hives)
- Worsening infection symptoms despite treatment
Warnings & Interactions
Do not use if allergic to atovaquone or any component of the formulation
Must be taken with food; low absorption may lead to treatment failure
Use with caution in patients with hepatic impairment; hepatotoxicity has been reported
Rifampin and rifabutin significantly reduce atovaquone levels; avoid coadministration
Tetracycline and metoclopramide may lower atovaquone concentrations
Patients with GI disorders may have reduced absorption; consider alternative therapy for severe PCP
Not studied for treatment of severe PCP
Tell your prescriber about all medications, supplements, and health conditions before starting atovaquone 750mg/5ml.
Sources & References
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