Malathion 0.5% Lotion

Generic For: Ovide

Malathion 0.5% lotion (brand name Ovide) is a prescription topical treatment for head lice in adults and children 6 years and older. It kills live lice and many lice eggs (nits) on the scalp and hair. After a licensed provider reviews your information, your order ships from a licensed U.S. pharmacy.

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7-day supply · $4.41/mL

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  3. Our licensed U.S. pharmacists fill your prescription
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Price: $260.00

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Buy Malathion 0.5% Lotion (Ovide) Online

A prescription pediculicide lotion for head lice and their eggs (nits)

Malathion 0.5% Lotion Quick Facts

Drug classTopical pediculicide (organophosphate)
TreatsHead lice, lice eggs (nits)
FormLiquid
Typical dosingApply the lotion by sprinkling on dry hair and rubbing in until the hair and scalp are thoroughly moistened. Wash your hands right away after using the medicine. Allow the hair to dry naturally
Prescription requiredYes — prescription only

What Is Malathion 0.5% Lotion?

Malathion 0.5% lotion is a prescription medication applied to the scalp and hair to treat head lice infestations. It is an organophosphate agent that works by attacking the nervous system of lice, killing live lice and many of their eggs (nits). Sold under the brand name Ovide, it is approved for use in adults and children 6 years of age and older. It is applied to dry hair, left on for 8 to 12 hours, and then washed out.

What Does Malathion 0.5% Lotion Treat?

Head lice (Pediculosis capitis) in patients 6 years and older
Killing live head lice on the scalp and hair
Killing lice eggs (nits) attached to hair shafts
Retreatment when live lice are seen 7–9 days after first use

Malathion 0.5% Lotion Dosage

Apply to dry hair and scalp until thoroughly wet; allow hair to dry naturally and leave uncovered.
After 8–12 hours, wash hair with shampoo, rinse, and remove dead lice and nits with a fine-tooth comb.
Repeat once after 7–9 days only if live lice are still present.

Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.

Malathion 0.5% Lotion Side Effects

Common side effects

  • Scalp irritation
  • Stinging or burning of the scalp
  • Skin redness at the application site
  • Scalp itching
  • Dryness of the scalp or hair
  • Mild eye irritation if fumes contact the eyes

Serious side effects

Stop taking this medication and seek medical attention right away if you experience:

  • Chemical burns of the scalp or skin
  • Severe skin irritation or blistering
  • Signs of allergic reaction (rash, swelling, difficulty breathing)
  • Eye injury from direct contact with the lotion
  • Symptoms after accidental swallowing (requires immediate medical attention)

Warnings & Interactions

Flammable — lotion and wet hair; avoid open flames, cigarettes, and electric heat sources such as hair dryers until hair is dry
For external use on scalp hair only; do not swallow
Not recommended for children under 6 years; contraindicated in neonates and infants
Avoid contact with eyes; flush immediately with water if exposed
Use on children only under adult supervision
Stop use and contact a provider if severe skin irritation occurs
Wash hands after applying

Tell your prescriber about all medications, supplements, and health conditions before starting malathion 0.5% lotion.

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Frequently Asked Questions

What is malathion lotion used for?

Malathion 0.5% lotion (Ovide) is a prescription treatment for head lice in adults and children 6 years and older. It kills live lice and many lice eggs (nits) on the scalp and hair.

Do I need a prescription for malathion lotion?

Yes. Malathion 0.5% lotion is a prescription-only medication in the United States. A licensed provider must review your health information before it can be dispensed.

How do I use malathion lotion?

Apply the lotion to dry hair and scalp until thoroughly wet, then let hair air dry uncovered. After 8 to 12 hours, shampoo, rinse, and comb out dead lice and nits with a fine-tooth comb. Repeat in 7 to 9 days only if live lice are still seen.

Is malathion lotion safe for children?

Malathion lotion is approved for children 6 years of age and older, used under adult supervision. It is not recommended for children under 6 and is contraindicated in neonates and infants.

Why can't I use a hair dryer with malathion lotion?

The lotion is alcohol-based and flammable, and hair remains flammable while wet with the product. Keep away from open flames, cigarettes, and electric heat sources such as hair dryers or curling irons until the hair is fully dry.

How does ordering and shipping work?

After you place your order, a licensed provider reviews your information to confirm the medication is appropriate. Once approved, your prescription is filled and shipped from a licensed U.S. pharmacy.