Clindamycin 1% Gel

Generic For: Cleocin T

Clindamycin 1% Gel (brand name Cleocin T) is a prescription topical antibiotic used to treat acne vulgaris. Unlike oral antibiotics such as amoxicillin, it is applied directly to the skin to reduce acne-causing bacteria and inflammatory lesions. After a licensed provider reviews your health information, your order ships from a licensed U.S. pharmacy.

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30-day supply · $1.17/gram

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  1. Select your medication
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  3. Our licensed U.S. pharmacists fill your prescription
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Price: $35.00

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Buy Clindamycin 1% Gel (Cleocin T) Online

Topical lincosamide antibiotic gel for acne vulgaris and inflammatory acne breakouts

Clindamycin 1% Gel Quick Facts

Drug classTopical lincosamide antibiotic
TreatsAcne vulgaris, inflammatory acne lesions
FormGel
Typical dosingApply a thin film to the clean dry affected area topically twice daily.
Prescription requiredYes — prescription only

What Is Clindamycin 1% Gel?

Clindamycin 1% Gel is a topical form of the antibiotic clindamycin, sold under the brand name Cleocin T. It works by slowing the growth of Cutibacterium acnes, the bacteria involved in acne, and by reducing inflammation in the skin. People often compare clindamycin vs amoxicillin, but the two are different: amoxicillin is an oral penicillin-class antibiotic, while topical clindamycin is applied to the skin specifically for acne. It is available by prescription only and is typically used once or twice daily as directed by your provider.

What Does Clindamycin 1% Gel Treat?

Acne vulgaris
Inflammatory acne lesions (papules and pustules)
Mild to moderate facial acne
Acne breakouts on the chest, back, or shoulders
Acne treatment as part of a provider-directed regimen

Clindamycin 1% Gel Dosage

Apply a thin film to the affected area topically twice daily.
For external use only; duration as directed by prescriber.

Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.

Clindamycin 1% Gel Side Effects

Common side effects

  • Skin dryness
  • Peeling or flaking
  • Burning or stinging at application site
  • Itching
  • Skin redness
  • Oily skin
  • Skin irritation

Serious side effects

Stop taking this medication and seek medical attention right away if you experience:

  • Severe or persistent diarrhea (possible C. difficile-associated colitis)
  • Bloody or watery stools
  • Severe abdominal cramps or pain
  • Severe allergic reaction (rash, swelling, difficulty breathing)
  • Severe skin irritation or blistering

Warnings & Interactions

Do not use with a history of regional enteritis, ulcerative colitis, or antibiotic-associated colitis
Stop use and contact your provider if significant diarrhea occurs
Avoid concurrent use with topical erythromycin (antagonistic effect)
For external use only; avoid eyes, mouth, and mucous membranes
May enhance the effect of neuromuscular blocking agents
Tell your provider if you are pregnant or breastfeeding

Tell your prescriber about all medications, supplements, and health conditions before starting clindamycin 1% gel.

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Frequently Asked Questions

Is clindamycin stronger than amoxicillin?

Neither is universally "stronger" — they belong to different antibiotic classes and treat different infections. Topical clindamycin gel is used for acne, while amoxicillin is an oral antibiotic used for infections like strep throat and ear infections. Your provider chooses the antibiotic based on the condition being treated.

What is the difference between clindamycin vs amoxicillin for acne?

Clindamycin gel is FDA-approved for acne vulgaris and is applied directly to the skin; amoxicillin is not a standard acne treatment. Because clindamycin works at the skin's surface, it targets acne-causing bacteria with less systemic exposure than an oral antibiotic.

Do I need a prescription for Clindamycin 1% Gel?

Yes. Clindamycin 1% Gel (Cleocin T) is a prescription-only medication in the U.S. A licensed provider must review your health information and determine it is appropriate before it can be dispensed.

How does ordering and shipping work?

After you complete your order and health questionnaire, a licensed provider reviews your information. If approved, the prescription is filled and shipped from a licensed U.S. pharmacy in discreet packaging.

How do I apply Clindamycin 1% Gel?

Wash and dry the affected area, then apply a thin film twice daily or as your prescriber directs. Avoid contact with the eyes, mouth, and broken skin, and wash your hands after applying.

How long does clindamycin gel take to work for acne?

Many people notice gradual improvement over several weeks of consistent use, though individual results vary. Continue using it as prescribed and follow up with your provider if your acne does not improve.