Clobetasol 0.05% Ointment

Generic For: Temovate

Clobetasol 0.05% ointment (brand name Temovate) is a super-high-potency topical corticosteroid used for short-term treatment of corticosteroid-responsive skin conditions such as plaque psoriasis and severe eczema. It works by reducing inflammation, itching, and redness. After a licensed provider reviews your prescription, your order ships from a licensed U.S. pharmacy.

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14-day supply · $0.83/gram

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Buy Clobetasol 0.05% Ointment (Temovate) Online

A super-high-potency topical corticosteroid ointment for psoriasis, eczema, and other inflammatory skin conditions

Clobetasol 0.05% Ointment Quick Facts

Drug classTopical corticosteroid (super-high potency)
TreatsPlaque psoriasis, eczema, dermatitis, lichen planus
FormOintment
Typical dosingApply to affected area topically 1-2 times daily as needed for skin irritation.
Prescription requiredYes — prescription only

What Is Clobetasol 0.05% Ointment?

Clobetasol 0.05% ointment is a prescription topical corticosteroid, one of the strongest available in its class. It is applied to the skin to relieve the inflammation and itching of corticosteroid-responsive dermatoses, including plaque psoriasis and severe eczema. Because of its potency, clobetasol is intended for short-term use on limited areas of the body. It is available as an ointment as well as other forms, such as clobetasol propionate foam, which your prescriber may choose based on the treatment area.

What Does Clobetasol 0.05% Ointment Treat?

Plaque psoriasis (moderate to severe)
Eczema (atopic dermatitis) flares
Contact dermatitis
Lichen planus
Lichen sclerosus
Discoid lupus erythematosus
Other corticosteroid-responsive dermatoses

Clobetasol 0.05% Ointment Dosage

Apply a thin layer to the affected area twice daily; rub in gently.
Limit treatment to 2 consecutive weeks; do not exceed 50 g per week.
Do not use with occlusive dressings unless directed by your prescriber.

Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.

Clobetasol 0.05% Ointment Side Effects

Common side effects

  • Burning or stinging at application site
  • Itching
  • Skin irritation
  • Dry or cracking skin
  • Skin thinning (atrophy)
  • Stretch marks (striae)
  • Redness
  • Folliculitis

Serious side effects

Stop taking this medication and seek medical attention right away if you experience:

  • Signs of adrenal suppression (fatigue, weakness, nausea)
  • Severe skin irritation or allergic reaction (rash, swelling)
  • Signs of skin infection (pus, worsening redness, warmth)
  • Vision changes or blurred vision
  • High blood sugar symptoms (increased thirst, urination)

Warnings & Interactions

For external use only; not for the face, groin, or underarms unless directed
Can suppress the HPA axis (adrenal function), especially with prolonged use or large areas
Do not use more than 50 g per week or longer than 2 consecutive weeks
Not recommended for children under 12 years
Do not cover treated areas with bandages or occlusive dressings unless instructed
Discontinue if skin infection develops and is not controlled
Tell your provider if pregnant or breastfeeding before use

Tell your prescriber about all medications, supplements, and health conditions before starting clobetasol 0.05% ointment.

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Frequently Asked Questions

What is clobetasol ointment used for?

Clobetasol 0.05% ointment is used for short-term treatment of inflammatory skin conditions that respond to corticosteroids, such as plaque psoriasis and severe eczema. It helps reduce redness, swelling, and itching.

Do I need a prescription for clobetasol?

Yes. Clobetasol is a prescription-only medication in the United States. A licensed provider must review your prescription before your order can be filled.

How does ordering and shipping work?

After you place your order, a licensed provider reviews your prescription. Once approved, your medication is dispensed and shipped from a licensed U.S. pharmacy to your address.

How strong is clobetasol compared to other steroid creams?

Clobetasol is a super-high-potency (Class I) topical corticosteroid, among the strongest available. Because of its strength, it is used for short periods and on limited skin areas as directed by your prescriber.

What is the difference between clobetasol ointment and clobetasol propionate foam?

Both contain the same active ingredient at 0.05% strength but in different vehicles. Ointments are often used for thick, dry plaques, while clobetasol propionate foam may be preferred for the scalp or hairy areas; your prescriber will choose the form that fits your condition.

How long can I use clobetasol ointment?

Per FDA labeling, treatment should generally be limited to 2 consecutive weeks, with no more than 50 grams used per week. Follow your prescriber's instructions and do not extend use without medical guidance.

Can I use clobetasol on my face?

Clobetasol should not be applied to the face, groin, or underarms unless your prescriber specifically directs it. These areas have thinner skin and are more prone to side effects such as skin thinning.