Estradiol 0.075 mg Patches (Once Weekly)
Generic For: Climara
Estradiol 0.075 mg patches (once weekly), sold under the brand name Climara, deliver estrogen through the skin to help manage moderate to severe menopausal symptoms such as hot flashes and vaginal dryness, and to help prevent postmenopausal osteoporosis. These estradiol patches are applied once weekly for steady hormone delivery. Your order ships from a licensed U.S. pharmacy after a licensed provider reviews your prescription.
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30-day supply · $20.00/patch
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Price: $80.00
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Buy Estradiol 0.075 mg Patches (Once Weekly) Online — Climara
An estrogen hormone therapy patch for menopausal hot flashes, vaginal dryness, and osteoporosis prevention
Estradiol 0.075 mg Patches (Once Weekly) Quick Facts
| Drug class | Estrogen hormone therapy |
|---|---|
| Treats | Menopausal hot flashes, vaginal dryness, osteoporosis prevention, low estrogen levels |
| Form | Patch |
| Typical dosing | Apply 1 patch to a clean dry area once weekly. |
| Prescription required | Yes — prescription only |
What Is Estradiol 0.075 mg Patches (Once Weekly)?
Estradiol 0.075 mg patches (once weekly), branded as Climara, are a transdermal form of estradiol, the primary estrogen hormone produced by the ovaries. Each patch is applied to the skin once a week and releases a steady dose of estrogen into the bloodstream. It is FDA-approved to treat moderate to severe vasomotor symptoms of menopause, such as hot flashes and night sweats, as well as symptoms of vulvar and vaginal atrophy. It is also used to treat low estrogen due to certain medical conditions and to help prevent postmenopausal osteoporosis.
What Does Estradiol 0.075 mg Patches (Once Weekly) Treat?
Moderate to severe hot flashes due to menopause
Moderate to severe vaginal dryness and irritation from menopause
Prevention of postmenopausal osteoporosis
Low estrogen due to hypogonadism
Low estrogen due to surgical removal of the ovaries (castration)
Low estrogen due to primary ovarian failure
Estradiol 0.075 mg Patches (Once Weekly) Dosage
Apply 1 patch (0.075 mg/day) transdermally to the lower abdomen once weekly.
Rotate application sites; do not apply to the breasts.
Use the lowest effective dose for the shortest duration, as directed by your prescriber.
Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.
Estradiol 0.075 mg Patches (Once Weekly) Side Effects
Common side effects
- Redness or irritation at the application site
- Headache
- Breast tenderness or pain
- Nausea
- Bloating
- Irregular vaginal bleeding or spotting
- Back pain
Serious side effects
Stop taking this medication and seek medical attention right away if you experience:
- Signs of blood clots (leg pain or swelling, chest pain, shortness of breath)
- Signs of stroke (sudden weakness, vision changes, slurred speech)
- Severe or unusual vaginal bleeding
- New breast lumps
- Yellowing of the skin or eyes (possible liver problems)
- Severe allergic reaction (rash, swelling, trouble breathing)
Warnings & Interactions
Boxed warning: estrogen therapy may increase the risk of endometrial cancer, stroke, blood clots, and (with progestin) breast cancer and probable dementia
Do not use if you have undiagnosed abnormal vaginal bleeding
Do not use with a history of breast cancer or estrogen-dependent cancer
Do not use with active or prior blood clots (DVT, PE), stroke, or heart attack
Do not use with liver disease or during pregnancy
Women with a uterus generally need a progestin to reduce endometrial cancer risk
Tell your provider about all medications, including CYP3A4 inducers/inhibitors such as St. John's wort, rifampin, and ketoconazole
Tell your prescriber about all medications, supplements, and health conditions before starting estradiol 0.075 mg patches (once weekly).
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