Estradiol 0.075mg Patches (Twice Weekly)
Generic For: Vivelle-Dot
Estradiol 0.075mg patches, applied twice weekly, are a transdermal form of estrogen (brand name Vivelle-Dot) used to treat moderate to severe menopause symptoms such as hot flashes and night sweats, and to help prevent postmenopausal osteoporosis. After a licensed provider reviews your prescription, your order ships from a licensed U.S. pharmacy.
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30-day supply · $11.88/patch
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Buy Estradiol 0.075mg Patches (Twice Weekly) Online — Vivelle-Dot
An estrogen hormone patch for menopause symptoms, hot flashes, and postmenopausal osteoporosis prevention
Estradiol 0.075mg Patches (Twice Weekly) Quick Facts
| Drug class | Estrogen hormone (transdermal) |
|---|---|
| Treats | Menopause symptoms, hot flashes, vaginal dryness, osteoporosis prevention |
| Form | Patch |
| Typical dosing | Apply 1 patch to a clean dry area twice weekly. |
| Prescription required | Yes — prescription only |
What Is Estradiol 0.075mg Patches (Twice Weekly)?
Estradiol 0.075mg (Vivelle-Dot) is a small transdermal patch that delivers estradiol, a form of estrogen, through the skin. It is worn continuously and replaced twice weekly, typically every 3 to 4 days. Because the hormone is absorbed through the skin rather than the digestive system, patches provide steady estrogen levels and bypass first-pass liver metabolism. It is prescribed to relieve moderate to severe symptoms of menopause and, in appropriate patients, to help prevent postmenopausal bone loss.
What Does Estradiol 0.075mg Patches (Twice Weekly) Treat?
Moderate to severe hot flashes and night sweats (vasomotor symptoms of menopause)
Moderate to severe vulvar and vaginal atrophy due to menopause
Prevention of postmenopausal osteoporosis
Hypoestrogenism due to hypogonadism
Hypoestrogenism due to castration or primary ovarian failure
Estradiol 0.075mg Patches (Twice Weekly) Dosage
Apply one 0.075 mg/day patch to a clean, dry area of the lower abdomen twice weekly (every 3 to 4 days).
Rotate application sites; do not apply to the breasts.
Use the lowest effective dose for the shortest duration consistent with treatment goals, as directed by your prescriber.
Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.
Estradiol 0.075mg Patches (Twice Weekly) Side Effects
Common side effects
- Skin irritation or redness at the application site
- Headache
- Breast tenderness
- Nausea
- Bloating or abdominal cramps
- Breakthrough bleeding or spotting
- Fluid retention
- Mood changes
Serious side effects
Stop taking this medication and seek medical attention right away if you experience:
- Signs of blood clots (leg pain/swelling, chest pain, sudden shortness of breath)
- Signs of stroke (sudden weakness, severe headache, vision or speech changes)
- Unusual or heavy vaginal bleeding
- New breast lumps
- Severe allergic reaction (hives, swelling of face or throat, trouble breathing)
- Yellowing of the skin or eyes (possible liver problems)
Warnings & Interactions
Boxed warning: estrogens may increase the risk of endometrial cancer, cardiovascular events, blood clots, stroke, and probable dementia in certain populations
Do not use if you have undiagnosed abnormal genital bleeding
Do not use with known, suspected, or history of breast cancer or estrogen-dependent cancer
Do not use with active or history of blood clots (DVT, PE), stroke, or heart attack
Do not use with known liver impairment or disease
Do not use during pregnancy
Women with a uterus generally need a progestin added to reduce endometrial cancer risk; CYP3A4 inducers/inhibitors may alter estradiol levels
Tell your prescriber about all medications, supplements, and health conditions before starting estradiol 0.075mg patches (twice weekly).
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