Glipizide ER 5mg
Generic For: Glucotrol XL
Glipizide ER 5mg (Glucotrol XL) is an extended-release sulfonylurea tablet that helps lower blood sugar in adults with type 2 diabetes. It works by stimulating the pancreas to release insulin and is used alongside diet and exercise. After a licensed provider reviews your prescription, your order ships from a licensed U.S. pharmacy.
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100-day supply · $0.35/tablet
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A sulfonylurea extended-release tablet for type 2 diabetes and blood sugar control
Glipizide ER 5mg Quick Facts
| Drug class | Sulfonylurea (antidiabetic) |
|---|---|
| Treats | Type 2 diabetes, high blood sugar |
| Form | Tablet |
| Typical dosing | Take by mouth as directed by Physician. |
| Prescription required | Yes — prescription only |
What Is Glipizide ER 5mg?
Glipizide ER is the extended-release form of glipizide, a prescription sulfonylurea sold under the brand name Glucotrol XL. It helps adults with type 2 diabetes control blood sugar by prompting the pancreas to release more insulin. The extended-release tablet delivers medication gradually, so it is typically taken once daily with breakfast. It is used together with diet and exercise, either alone or with other diabetes medicines.
What Does Glipizide ER 5mg Treat?
Type 2 diabetes mellitus (adjunct to diet and exercise)
Improving glycemic control in adults
Lowering blood glucose when diet and exercise alone are not enough
Use in combination with other antidiabetic agents when needed
Glipizide ER 5mg Dosage
Start: 5 mg by mouth once daily with breakfast.
Titrate based on glycemic response; usual range 5–10 mg once daily.
Maximum: 20 mg once daily. Swallow whole; do not crush, chew, or divide.
Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.
Glipizide ER 5mg Side Effects
Common side effects
- Low blood sugar (hypoglycemia)
- Dizziness
- Nervousness or tremor
- Diarrhea
- Gas (flatulence)
- Headache
- Nausea
Serious side effects
Stop taking this medication and seek medical attention right away if you experience:
- Severe or prolonged hypoglycemia (confusion, seizures, loss of consciousness)
- Allergic reaction (rash, hives, swelling, difficulty breathing)
- Liver problems (jaundice, dark urine)
- Low blood cell counts (unusual bleeding, bruising, fatigue)
- Severe skin reactions
Warnings & Interactions
Do not use in type 1 diabetes or diabetic ketoacidosis
Contraindicated with known hypersensitivity to glipizide or sulfonamides
Risk of hypoglycemia, especially with missed meals, alcohol, or renal/hepatic impairment
Sulfonylureas may be associated with increased cardiovascular mortality (class warning)
Use caution with beta-blockers, which can mask hypoglycemia symptoms
Interacts with fluconazole, NSAIDs, and other drugs that alter blood sugar
Do not crush or chew; tell your doctor if you have GI narrowing (tablet shell may not pass)
Tell your prescriber about all medications, supplements, and health conditions before starting glipizide er 5mg.
Sources & References
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