Metformin 500mg
Generic For: Glucophage
Metformin 500mg (brand name Glucophage) is an oral biguanide medication used alongside diet and exercise to improve blood sugar control in adults and children with type 2 diabetes. It is one of the most commonly prescribed diabetes medications in the United States. Your order ships from a licensed U.S. pharmacy after a licensed provider reviews your prescription.
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50-day supply · $0.20/tablet
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Buy Metformin 500mg Online
A biguanide medication for type 2 diabetes and blood sugar control
Metformin 500mg Quick Facts
| Drug class | Biguanide antidiabetic |
|---|---|
| Treats | Type 2 diabetes, high blood sugar |
| Form | Tablet |
| Typical dosing | Take 1 tablet by mouth once or twice daily. |
| Prescription required | Yes — prescription only |
What Is Metformin 500mg?
Metformin is an oral medication in the biguanide class, sold under the brand name Glucophage. It helps lower blood sugar by reducing the amount of glucose your liver produces and improving how your body responds to insulin. Metformin is FDA-approved to improve glycemic control in people with type 2 diabetes when used with diet and exercise. It does not typically cause low blood sugar when used alone and is often the first medication prescribed for type 2 diabetes.
What Does Metformin 500mg Treat?
Type 2 diabetes mellitus in adults
Type 2 diabetes mellitus in children 10 years and older
Improving glycemic control alongside diet and exercise
Use alone or in combination with other diabetes medications
Use in combination with insulin when needed
Metformin 500mg Dosage
Start: 500 mg by mouth twice daily with meals
Titrate: increase by 500 mg weekly as tolerated
Maximum: 2550 mg per day in divided doses
Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.
Metformin 500mg Side Effects
Common side effects
- Diarrhea
- Nausea
- Upset stomach or indigestion
- Gas or bloating
- Stomach pain
- Metallic taste
- Decreased appetite
- Headache
Serious side effects
Stop taking this medication and seek medical attention right away if you experience:
- Lactic acidosis (muscle pain, trouble breathing, unusual tiredness, feeling cold)
- Low blood sugar when combined with insulin or sulfonylureas
- Vitamin B12 deficiency with long-term use
- Severe allergic reaction (rash, swelling, difficulty breathing)
- Signs of kidney problems (change in urination, swelling)
Warnings & Interactions
Boxed warning: risk of lactic acidosis, a rare but serious complication
Do not use with severe kidney impairment (eGFR below 30 mL/min/1.73 m²)
Do not use with metabolic acidosis or diabetic ketoacidosis
Temporarily stop before iodinated contrast imaging procedures as directed
Limit alcohol use; excessive alcohol increases lactic acidosis risk
Use caution with liver disease, heart failure, or dehydration
Tell your provider about all medications, including carbonic anhydrase inhibitors
Tell your prescriber about all medications, supplements, and health conditions before starting metformin 500mg.
Sources & References
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