Metformin ER 750mg
Generic For: Glucophage
Metformin ER 750mg (brand name Glucophage XR) is an extended-release biguanide medication used alongside diet and exercise to improve blood sugar control in adults with type 2 diabetes. It is one of the most commonly prescribed first-line treatments for type 2 diabetes. After a licensed provider reviews your prescription, your order ships from a licensed U.S. pharmacy.
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100-day supply · $0.25/tablet
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Price: $25.00
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Buy Metformin ER 750mg Online
An extended-release biguanide for type 2 diabetes and blood sugar control
Metformin ER 750mg Quick Facts
| Drug class | Biguanide antidiabetic |
|---|---|
| Treats | Type 2 diabetes, blood sugar control |
| Form | Tablet |
| Typical dosing | Take 1 tablet by mouth once daily with the evening meal. |
| Prescription required | Yes — prescription only |
What Is Metformin ER 750mg?
Metformin ER is an extended-release form of metformin, a biguanide medication that helps lower blood sugar in adults with type 2 diabetes. It works by reducing the amount of glucose your liver produces, decreasing glucose absorption in the intestines, and improving your body's sensitivity to insulin. The extended-release tablet dissolves slowly, allowing once-daily dosing and often causing fewer stomach-related side effects than immediate-release metformin. It is used together with diet and exercise, and may be taken alone or with other diabetes medications.
What Does Metformin ER 750mg Treat?
Type 2 diabetes mellitus in adults
Improving glycemic (blood sugar) control
Adjunct to diet and exercise
Used alone or in combination with other antidiabetic medications, including insulin
Metformin ER 750mg Dosage
Take 750mg by mouth once daily with the evening meal.
Dose may be increased by 750mg weekly as directed by your provider.
Maximum: 2000mg once daily; swallow whole — do not crush or chew.
Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.
Metformin ER 750mg Side Effects
Common side effects
- Diarrhea
- Nausea
- Upset stomach or indigestion
- Gas (flatulence)
- Abdominal discomfort
- Headache
- Metallic taste
- Decreased vitamin B12 levels with long-term use
Serious side effects
Stop taking this medication and seek medical attention right away if you experience:
- Lactic acidosis (muscle pain, trouble breathing, unusual tiredness, stomach pain, feeling cold)
- Severe hypoglycemia, especially when combined with insulin or sulfonylureas
- Signs of vitamin B12 deficiency (numbness, tingling, anemia)
- Severe allergic reaction (rash, swelling, difficulty breathing)
- Signs of kidney problems (change in urination, swelling)
Warnings & Interactions
Boxed warning: rare but serious risk of lactic acidosis; seek emergency care if symptoms occur
Contraindicated in severe kidney impairment (eGFR below 30 mL/min/1.73m²)
Contraindicated in metabolic acidosis, including diabetic ketoacidosis
Temporarily stop before iodinated contrast imaging procedures as directed
Avoid excessive alcohol use, which increases lactic acidosis risk
Use caution with carbonic anhydrase inhibitors (e.g., topiramate) and other drugs affecting kidney function
Not for treating type 1 diabetes
Tell your prescriber about all medications, supplements, and health conditions before starting metformin er 750mg.
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